Seasonal pattern of peptic ulcer hospitalizations: Analysis of the hospital discharge data of the Emilia-Romagna region of Italy

BMC Gastroenterology

Volumn 10, Issue , 2010, Pages

  Manfredini, Roberto ^a,b   Giorgio, Roberto De ^c   Smolensky, Michael H ^d   Boari, Benedetta ^e   Salmi, Raffaella ^e   Fabbri, Davide ^e   Contato, Edgardo ^f   Serra, Mauro ^c   Barbara, Giovanni ^c   Stanghellini, Vincenzo ^c   Corinaldesi, Roberto ^c   Gallerani, Massimo ^e  

^a Hospital of the Delta   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d The University of Texas at Austin   (United States)

^e UNIVERSITY HOSPITAL OF FERRARA   (Italy)

^f Epidemiology Unit   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AGE DISTRIBUTION; AGED; ARTICLE; AUTUMN; CHRONOBIOLOGY; CONTROLLED STUDY; DUODENUM ULCER; FEMALE; HEALTH STATISTICS; HIGH RISK PATIENT; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; INTESTINAL BLEEDING; INTESTINE PERFORATION; ITALY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PEPTIC ULCER; PREVALENCE; SEASONAL VARIATION; SEX DIFFERENCE; SPRING; STOMACH ULCER; SUMMER; WINTER; COMPARATIVE STUDY; FOLLOW UP; RETROSPECTIVE STUDY; SEASON; STATISTICAL ANALYSIS; STATISTICS;

AGED; DATA INTERPRETATION, STATISTICAL; DUODENAL ULCER; FEMALE; FOLLOW-UP STUDIES; HOSPITALIZATION; HUMANS; ITALY; MALE; PATIENT DISCHARGE; PEPTIC ULCER; PREVALENCE; RETROSPECTIVE STUDIES; SEASONS; STOMACH ULCER;

EID: 77950839231     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/1471-230X-10-37     Document Type: Article

References (53)

1. McGuigan JE. Peptic ulcer and gastritis. Harrison's Principles of Internal Medicine 1991, 1229-1248. New York: McGraw-Hill, Wilson JD, Braunwald E, Isselbacher KJ, Petersdorf RG, Martin JB, Fauci AS, Root RK, 12.
2. Spencer FA, Goldberg RJ, Becker RC, Gore JM, . for the Participants in the National Registry of Myocardial Infarction Seasonal distribution of acute myocardial infarction in the Second National Registry of Myocardial Infarction. J Am Coll Cardiol 1998, 31(6):1226-1233. 10.1016/S0735-1097(98)00098-9, 9581712, for the Participants in the National Registry of Myocardial Infarction.
3. Arntz HR, Willich SN, Schreiber C, Brüggemann T, Stern R, Schultheiss HP. Diurnal, weekly and seasonal variation of sudden death. Population-based analysis of 24061 consecutive cases. Eur Heart J 2000, 21(4):315-320. 10.1053/euhj.1999.1739, 10653679.
4. Manfredini R, Manfredini F, Boari B, Bergami E, Mari E, Gamberini S, Salmi R, Gallerani M. Seasonal and weekly patterns of hospital admissions for nonfatal and fatal myocardial infarction. Am J Emerg Med 2009, 27(9):1096-1102.
5. Mehta RH, Manfredini R, Hassan F, Sechtem U, Bossone E, Oh J, Cooper JV, Smith DE, Portaluppi F, Penn M, Hutchinson S, Nienaber CA, Isselbacher EM, Eagle KA. Chronobiological patterns of acute aortic dissection. Circulation 2002, 106(9):1110-1115. 10.1161/01.CIR.0000027568.39540.4B, 12196337.
6. Manfredini R, Boari B, Gallerani M, Salmi R, Bossone E, Distante A, Eagle KA, Mehta RH. Chronobiology of rupture and dissection of aortic aneurysms. J Vasc Surg 2004, 40(2):382-388. 10.1016/j.jvs.2004.04.019, 15297840.
7. Manfredini R, Gallerani M, Portaluppi F, Salmi R, Fersini C. Chronobiological patterns of onset of acute cerebrovascular diseases. Thromb Res 1997, 88(6):451-463. 10.1016/S0049-3848(97)00286-7, 9610956.
8. Gallerani M, Boari B, Smolensky MH, Salmi R, Fabbri D, Contato E, Manfredini R. Seasonal variation in occurrence of pulmonary embolism: analysis of the database of the Emilia-Romagna region. Chronobiol Int 2007, 24(1):143-160. 10.1080/07420520601139755, 17364585.
9. Manfredini R, Imberti D, Gallerani M, Verso M, Pistelli R, Ageno W, Agnelli G. Seasonal variation in the occurrence of venous thromboembolism: data from the MASTER registry. Clin Appl Thromb Hemost 2009, 15(3):309-315. 10.1177/1076029608319947, 18544594.
10. Mojòn A, Fernandez JR, Hermida RC. Chronolab: an interactive software package for chronobiologic time series analysis written for the Macintosh Computer. Chronobiol Int 1992, 9(6):403-412. 10.3109/07420529209064552, 1473193.
11. Yuan Y, Padol IT, Hunt RH. Peptic ulcer disease today. Nat Clin Pract Gastroenterol Hepatol 2006, 3(2):80-89. 10.1038/ncpgasthep0393, 16456574.
12. Laine L, Takeuchi K, Tarnawski A. Gastric mucosal defense and cytoprotection: bench to bedside. Gastroenterology 2008, 135(1):41-60. 10.1053/j.gastro.2008.05.030, 18549814.
13. El-Omar EM, Penman ID, Ardill JE, Chittajallu RS, Howie C, McColl KE. Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease. Gastroenterology 1995, 109(3):681-691. 10.1016/0016-5085(95)90374-7, 7657096.
14. Van Leerdam ME. Epidemiology of acute upper gastrointestinal bleeding. Best Pract Res Clin Gastroenterol 2008, 22(2):209-224. 10.1016/j.bpg.2007.10.011, 18346679.
15. Gallerani M, Simonato M, Manfredini R, Volpato S, Vigna GB, Fellin R, . for the Investigators of the GIFA Study (Gruppo Italiano di Farmacovigilanza nell'Anziano) Risk of hospitalization for upper gastrointestinal tract bleeding. J Clin Epidemiol 2004, 57(1):103-110. 10.1016/S0895-4356(03)00255-5, 15019017, for the Investigators of the GIFA Study (Gruppo Italiano di Farmacovigilanza nell'Anziano).
16. Tarquini B, Vener KJ. Temporal aspects of the pathophysiology of human ulcer disease. Chronobiol Int 1987, 4(1):75-89. 10.3109/07420528709078511, 3315260.
17. Moore JG, Smolensky M. Biological rhythms in gastrointestinal function and processes: implications for the pathogenesis and treatment of peptic ulcer disease. Ulcer Disease. Investigation and Basis for Therapy 1991, 55-85. New York: Marcel Dekker, Swabb EA, Szabo S.
18. Ergun GA, Rigas B. Circadian periodicity of the time of onset of acute lower gastrointestinal bleeding. Prog Clin Biol Res 1990, 341B:221-228.
19. Manfredini R, Gallerani M, Salmi R, Calò G, Pasin M, Bigoni M, Fersini C. Circadian variation in the time of onset of acute gastrointestinal bleeding. J Emerg Med 1994, 12(1):5-9. 10.1016/0736-4679(94)90003-5, 8163806.
20. Minoli G, Terrazzi V, Imperiali G, Frigerio G, Colombo E, Comin U, Corsini G, Curzio M, Prada A, Rocca F. Biphasic diurnal periodicity in bleeding from peptic ulcer. Am J Gastroenterol 1984, 89(1):72-78.
21. Siringo S, Bolondi L, Sofia S, Hermida RC, Gramantieri L, Gaiani S, Piscaglia F, Carbone C, Misitano B, Corinaldesi R. Circadian occurrence of variceal bleeding in patients with liver cirrhosis. J Gastroenterol Hepatol 1996, 11(12):1115-1120. 10.1111/j.1440-1746.1996.tb01838.x, 9034929.
22. Merican I, Sprengers D, McCormick PA, Minoli G, McIntyre N, Burroughs AK. Diurnal pattern of variceal bleeding in cirrhotic patients. J Hepatol 1993, 19(1):15-22. 10.1016/S0168-8278(05)80171-0, 8301035.
23. Sonnenberg A, Wasserman IH, Jacobsen SJ. Monthly variation of hospital admission and mortality of peptic ulcer disease: a reappraisal of ulcer periodicity. Gastroenterology 1992, 103(4):1192-1198.
24. Liu D, Gao A, Tang G, Yang W. Study of the relationship between the onset of peptic ulcers and metereological factors. Chin Med J 2003, 116(12):1940-1942.
25. Scholtyssek S, Allmendinger G, Blaich E, Schmid E. Seasonal incidence of duodenal ulcer - a myth?. Z Gastroenterol 1986, 24(4):175-178.
26. Savarino V, Mela GS, Zentilin P, Lapertosa G, Cutela P, Mele MR, Mansi C, Dallorto E, Vassallo A, Celle G. Are duodenal ulcer seasonal fluctuations paralleled by seasonal changes in 24-hour gastric acidity and Helicobacter pilori infection?. J Clin Gastroenterol 1996, 22(3):178-181. 10.1097/00004836-199604000-00005, 8724253.
27. Marbella A, Graham D, Smolensky MH. Seasonal variation in the incidence of bleeding ulcer. Ann Rev Chronopharmacol 1988, 5(2):307-309.
28. Tishchenko AM, Brusnitsyna MP, Boiko VV. The seasonality of acute hemorrhages in gastroduodenal ulcers. Vrach Delo 1990, 5(1):11-14.
29. Shih SC, Lin TH, Kao CR. Seasonal variation of peptic ulcer hemorrhage. Zhonghua Yi Xue Za Zhi 1993, 52(4):258-261.
30. Tsai CJ, Lin CY. Seasonal changes in symptomatic duodenal ulcer activity in Taiwan: a comparison between subjects with and without haemorrhage. J Intern Med 1998, 244(5):405-410. 10.1046/j.1365-2796.1998.00383.x, 9845856.
31. Nomura T, Ohkusa T, Araki A, Chuganji Y, Momoi M, Takashimizu I, Watanabe M. Influence of climatic factors in the incidence of upper gastrointestinal bleeding. J Gastroenterol Hepatol 2001, 16(6):619-623. 10.1046/j.1440-1746.2001.02486.x, 11422613.
32. Thomopoulos KC, Katsakoulis EC, Margaritis VG, Mimidis KP, Vagianos CE, Nikopoulou VN. Seasonality in the prevalence of acute upper gastrointestinal bleeding. J Clin Gastroenterol 1997, 25(4):576-579. 10.1097/00004836-199712000-00004, 9451665.
33. Yen FS, Wu JC, Wang LM, Kuo BI, Hu SC, Lee SD. Seasonal variation in the incidence of peptic ulcer and esophageal variceal bleeding in Taiwan. Zhonghua Yi Xue Za Zhi 1996, 57(1):22-27.
34. Rodrìguez HH, Loera OE, Almaràz LC, Jimenez RN, Solano RA, Jacobo KJS. Peptic ulcer with hemorrhage. An analysis of hospital discharges. Rev Gastroenterol Mex 1999, 64(1):6-11.
35. Lopez-Cepero JM, Lopez-Silva ME, Amaya-Vidal A, Alcaraz-Garcia S, Cavon-Blanco M, Castro T, Esteban-Alvarez A, Ferre-Alamo A, Benitez-Roldan A. Influence of climatic factors on the incidence of upper gastrointestinal bleeding. Gastroenterol Hepatol 2005, 28(9):540-545. 10.1157/13080601, 16277960.
36. Svanes C, Sothern RB, Sorbye H. Rhythmic patterns in incidence of peptic ulcer perforation over 5.5 decades in Norway. Chronobiol Int 1998, 15(3):241-264. 10.3109/07420529808998687, 9653578.
37. Adler J, Ingram D, House T. Perforated peptic ulcer - a seasonal disease?. Aust N Z J Surg 1984, 54(1):59-61. 10.1111/j.1445-2197.1984.tb06686.x, 6586169.
38. Christensen A, Hansen CP, Thagaard C, Lanng C. Seasonal periodicity of perforated gastric ulcer. Dan Med Bull 1988, 35(3):281-282.
39. Wysocki A, Kaminski W, Krzywon J. Seasonal periodicity of perforated peptic ulcers. Przegl Lek 1999, 56(3):189-191.
40. Kocer B, Surmeli S, Solak C, Unal B, Bozkurt B, Yildirim O, Dolapci M, Cengiz O. Factors affecting mortality and morbidity in patients with peptic ulcer perforation. J Gastroenterol Hepatol 2007, 22(4):565-570. 10.1111/j.1440-1746.2006.04500.x, 17376052.
41. Bendahan J, Gilboa S, Paran H, Neufeld D, Pomerantz I, Novis B, Freund U. Seasonal pattern in the incidence of bleeding caused by peptic ulcer in Israel. Am J Gastroenterol 1992, 87(6):733-735.
42. Csendes A, Medina E, Korn O, Rodas J, Mosquera M, Blanco C, Csendes P. Epidemiological and etiological aspects of upper digestive hemorrhage. Multicenter study in nine Chilean hospitals (1980-1990). Rev Med Chil 1995, 123(3):298-305.
43. Janik J, Chwirot P. Perforated peptic ulcer - time trends and patterns over 20 years. Med Sci Monit 2000, 6(2):369-372.
44. Budzynski P, Pogoda W, Pogodzinski M. Seasonal variation and influence of atmospheric pressure diurnal fluctuations on occurrence of acute complications in patients with stomach and duodenal ulcers. Przegl Lek 2000, 57(11):611-613.
45. Liu DY, Gao AN, Tang GD, Yang WY, Qin J, Wu XG, Zhu DC, Wang GN, Liu JJ, Liang ZH. Relationship between onset of peptic ulcer and meteorological factors. World J Gastroenterol 2006, 12(9):1463-1467.
46. Xirasagar S, Lin HC, Chen CS. Role of meteorological factors in duodenal ulcer seasonality: a nation-wide, population-based study. J Gen Intern Med 2007, 22(10):1439-1446. 10.1007/s11606-007-0288-z, 2305852, 17668271.
47. Raschka C, Schorr W, Koch HJ. Is there seasonal periodicity in the prevalence of Helicobacter pylori?. Chronobiol Int 1999, 16(6):811-819. 10.3109/07420529909016947, 10584180.
48. Lévi F, Le Louarn C, Reinberg A. Timing optimizes sustained-release indomethacin treatment of osteoarthritis. Clin Pharmacol Ther 1985, 37(1):77-84.
49. Perpoint B, Mismetti P, Simitsidis S, Hocquart J, Rambaud C, Buchmuller A, Queneau P, Decousus H. Dosing time optimizes sustained-release ketoprofen treatment of osteoarthritis. Chronobiol Int 1994, 11(2):119-125. 10.3109/07420529409055898, 8033240.
50. Moore JG, Goo R. Day and night aspirin-induced gastric mucosal damage and protection by ranitidine in man. Chronobiol Int 1987, 4(1):111-116. 10.3109/07420528709078514, 3677213.
51. Leng E. Monthly variations in drug-induced gastric ulcers in rats. Int J Biometeorol 1978, 22(2):190-196. 10.1007/BF01555397, 753792.
52. Fitzgerald JL, Mulford HA. Seasonal changes in alcohol consumption and related problems in Iowa, 1979-1980. J Stud Alcohol 1984, 45(4):363-368.
53. McKee M, Sanderson C, Chenet L, Vassin S, Shkolnikov V. Seasonal variation in mortality in Moscow. J Public Health Med 1998, 20(3):268-274.