메뉴 건너뛰기




Volumn 10, Issue 2, 2010, Pages 157-163

Targeting ovarian cancer-initiating cells

Author keywords

Cancer stem cells; Cancer initiating cells; Dormancy; Epigenetics; Ovarian cancer; Quiescence; Spheroids

Indexed keywords

8 QUINOLINOL; BRCA1 PROTEIN; BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; CELL SURFACE MARKER; DAIDZEIN; GENISTEIN; HERMES ANTIGEN; I KAPPA B; MICRORNA; PYRROLIDINEDITHIOCARBAMATE; SALINOMYCIN; STEM CELL FACTOR RECEPTOR; TEMOZOLOMIDE; TRANSCRIPTION FACTOR HOXA10; TRANSCRIPTION FACTOR MSX2; UNCLASSIFIED DRUG;

EID: 77950838834     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152010790909272     Document Type: Review
Times cited : (28)

References (104)
  • 3
    • 84984766699 scopus 로고    scopus 로고
    • A glossary for stem-cell biology
    • Smith, A. A glossary for stem-cell biology. Nature, 2006, 441, 1060.
    • (2006) Nature , vol.441 , pp. 1060
    • Smith, A.1
  • 6
    • 0033053009 scopus 로고    scopus 로고
    • The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: Does the emperor have no clothes?
    • Dubeau, L. The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes? Gynecol. Oncol., 1999, 72(3), 437-442.
    • (1999) Gynecol. Oncol. , vol.72 , Issue.3 , pp. 437-442
    • Dubeau, L.1
  • 8
    • 55149119938 scopus 로고    scopus 로고
    • The relationship of endometriosis and ovarian malignancy: A review
    • Nezhat, F.; Datta, M.S.; Hanson, V.; Pejovic, T.; Nezhat, C. The relationship of endometriosis and ovarian malignancy: a review. Fertil. Steril., 2008, 90(5), 1559-1570.
    • (2008) Fertil. Steril. , vol.90 , Issue.5 , pp. 1559-1570
    • Nezhat, F.1    Datta, M.S.2    Hanson, V.3    Pejovic, T.4    Nezhat, C.5
  • 10
    • 84942748575 scopus 로고    scopus 로고
    • Development and differentiation of the ovarian surface epithelium: Cues for the basis of its malignant potential
    • Leung, P. C. T.; Adashi, E. Y., Eds. 2nd ed.; Elsevier Academic Press: San Diego
    • Auersperg, N.; Woo, M.M.M. Development and differentiation of the ovarian surface epithelium: cues for the basis of its malignant potential. In The Ovary; Leung, P. C. T.; Adashi, E. Y., Eds. 2nd ed.; Elsevier Academic Press: San Diego, 2004; pp. 579-590.
    • (2004) The Ovary , pp. 579-590
    • Auersperg, N.1    Woo, M.M.M.2
  • 11
    • 39749180158 scopus 로고    scopus 로고
    • Ovarian cancer and oral contraceptives: Collaborative reanalysis of data from 45 epidemiological studies including 23,257 women with ovarian cancer and 87,303 controls
    • Collaborative Group on Epidemiological Studies of
    • Collaborative Group on Epidemiological Studies of Ovarian, C.; Beral, V.; Doll, R.; Hermon, C.; Peto, R.; Reeves, G. Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies including 23,257 women with ovarian cancer and 87,303 controls. Lancet, 2008, 371(9609), 303-314.
    • (2008) Lancet , vol.371 , Issue.9609 , pp. 303-314
    • Ovarian, C.1    Beral, V.2    Doll, R.3    Hermon, C.4    Peto, R.5    Reeves, G.6
  • 12
    • 0034754436 scopus 로고    scopus 로고
    • Ovulationinduced DNA damage in ovarian surface epithelial cells of ewes: Prospective regulatory mechanisms of repair/survival and apoptosis
    • Murdoch, W.J.; Townsend, R.S.; McDonnel, A.C. Ovulationinduced DNA damage in ovarian surface epithelial cells of ewes: prospective regulatory mechanisms of repair/survival and apoptosis. Biol. Reprod., 2001, 65(5), 1417-1424.
    • (2001) Biol. Reprod. , vol.65 , Issue.5 , pp. 1417-1424
    • Murdoch, W.J.1    Townsend, R.S.2    McDonnel, A.C.3
  • 13
    • 2942594342 scopus 로고    scopus 로고
    • Oxidative damage to DNA of ovarian surface epithelial cells affected by ovulation: Carcinogenic implication and chemoprevention
    • Murdoch, W.J.; Martinchick, J.F. Oxidative damage to DNA of ovarian surface epithelial cells affected by ovulation: carcinogenic implication and chemoprevention. Exp. Biol. Med., 2004, 229(6), 546-552.
    • (2004) Exp. Biol. Med. , vol.229 , Issue.6 , pp. 546-552
    • Murdoch, W.J.1    Martinchick, J.F.2
  • 14
    • 25144479318 scopus 로고    scopus 로고
    • Carcinogenic potential of ovulatory genotoxicity
    • Murdoch, W.J. Carcinogenic potential of ovulatory genotoxicity. Biol. Reprod., 2005, 73(4), 586-590.
    • (2005) Biol. Reprod. , vol.73 , Issue.4 , pp. 586-590
    • Murdoch, W.J.1
  • 15
    • 55949089955 scopus 로고    scopus 로고
    • New insights into the pathogenesis of serous ovarian cancer and its clinical impact
    • Levanon, K.; Crum, C.; Drapkin, R. New insights into the pathogenesis of serous ovarian cancer and its clinical impact. J. Clin. Oncol., 2008, 26(32), 5284-5293.
    • (2008) J. Clin. Oncol. , vol.26 , Issue.32 , pp. 5284-5293
    • Levanon, K.1    Crum, C.2    Drapkin, R.3
  • 16
    • 0029090088 scopus 로고
    • Ovarian dysplasia in epithelial inclusion cysts. A morphometric approach using neural networks
    • Deligdisch, L.; Einstein, A.J.; Guera, D.; Gil, J. Ovarian dysplasia in epithelial inclusion cysts. A morphometric approach using neural networks. Cancer, 1995, 76(6), 1027-1034.
    • (1995) Cancer , vol.76 , Issue.6 , pp. 1027-1034
    • Deligdisch, L.1    Einstein, A.J.2    Guera, D.3    Gil, J.4
  • 17
    • 0029089245 scopus 로고
    • Early de novo ovarian cancer and cancer developing in benign ovarian lesions
    • Scully, R.E. Early de novo ovarian cancer and cancer developing in benign ovarian lesions. Int. J. Gynaecol. Obstet., 1995, 49 (Suppl.), S9-15.
    • (1995) Int. J. Gynaecol. Obstet. , vol.49 , Issue.SUPPL.
    • Scully, R.E.1
  • 18
    • 0029437995 scopus 로고
    • Pathology of ovarian cancer precursors
    • Scully, R.E. Pathology of ovarian cancer precursors. J. Cell Biochem. Suppl., 1995, 23, 208-218.
    • (1995) J. Cell Biochem. Suppl. , vol.23 , pp. 208-218
    • Scully, R.E.1
  • 19
    • 56749103412 scopus 로고    scopus 로고
    • The cell of origin of ovarian epithelial tumours
    • Dubeau, L. The cell of origin of ovarian epithelial tumours. Lancet Oncol., 2008, 9(12), 1191-1197.
    • (2008) Lancet Oncol. , vol.9 , Issue.12 , pp. 1191-1197
    • Dubeau, L.1
  • 20
    • 0346251021 scopus 로고    scopus 로고
    • Atypical epithelial proliferation in fallopian tubes in prophylactic salpingo-oophorectomy specimens from BRCA1 and BRCA2 germline mutation carriers
    • Carcangiu, M.L.; Radice, P.; Manoukian, S.; Spatti, G.; Gobbo, M.; Pensotti, V.; Crucianelli, R.; Pasini, B. Atypical epithelial proliferation in fallopian tubes in prophylactic salpingo-oophorectomy specimens from BRCA1 and BRCA2 germline mutation carriers. Int. J. Gynecol. Pathol., 2004, 23(1), 35-40.
    • (2004) Int. J. Gynecol. Pathol. , vol.23 , Issue.1 , pp. 35-40
    • Carcangiu, M.L.1    Radice, P.2    Manoukian, S.3    Spatti, G.4    Gobbo, M.5    Pensotti, V.6    Crucianelli, R.7    Pasini, B.8
  • 23
    • 42949138321 scopus 로고    scopus 로고
    • A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations
    • Folkins, A.K.; Jarboe, E.A.; Saleemuddin, A.; Lee, Y.; Callahan, M.J.; Drapkin, R.; Garber, J.E.; Muto, M.G.; Tworoger, S.; Crum, C.P. A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations. Gynecol. Oncol., 2008, 109(2), 168-173.
    • (2008) Gynecol. Oncol. , vol.109 , Issue.2 , pp. 168-173
    • Folkins, A.K.1    Jarboe, E.A.2    Saleemuddin, A.3    Lee, Y.4    Callahan, M.J.5    Drapkin, R.6    Garber, J.E.7    Muto, M.G.8    Tworoger, S.9    Crum, C.P.10
  • 25
    • 0026009119 scopus 로고
    • Pathology of the fallopian tube, broad ligament, peritoneum, and pelvic soft tissues
    • Thor, A.D.; Young, R.H.; Clement, P.B. Pathology of the fallopian tube, broad ligament, peritoneum, and pelvic soft tissues. Hum. Pathol., 1991, 22(9), 856-867.
    • (1991) Hum. Pathol. , vol.22 , Issue.9 , pp. 856-867
    • Thor, A.D.1    Young, R.H.2    Clement, P.B.3
  • 26
    • 14944372435 scopus 로고    scopus 로고
    • Molecular regulation of mullerian development by Hox genes
    • Du, H.; Taylor, H.S. Molecular regulation of mullerian development by Hox genes. Ann. N. Y. Acad. Sci., 2004, 1034, 152-165.
    • (2004) Ann. N. Y. Acad. Sci. , vol.1034 , pp. 152-165
    • Du, H.1    Taylor, H.S.2
  • 27
    • 18344373769 scopus 로고    scopus 로고
    • Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract
    • Cheng, W.; Liu, J.; Yoshida, H.; Rosen, D.; Naora, H. Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract. Nat. Med., 2005, 11(5), 531-537.
    • (2005) Nat. Med. , vol.11 , Issue.5 , pp. 531-537
    • Cheng, W.1    Liu, J.2    Yoshida, H.3    Rosen, D.4    Naora, H.5
  • 28
    • 25444481792 scopus 로고    scopus 로고
    • Developmental patterning in the wrong context: The paradox of epithelial ovarian cancers
    • Naora, H. Developmental patterning in the wrong context: the paradox of epithelial ovarian cancers. Cell Cycle, 2005, 4(8), 1033-1035.
    • (2005) Cell Cycle , vol.4 , Issue.8 , pp. 1033-1035
    • Naora, H.1
  • 29
    • 0017785769 scopus 로고
    • Primary bioassay of human tumor stem cells
    • Hamburger, A.W.; Salmon, S.E. Primary bioassay of human tumor stem cells. Science, 1977, 197(4302), 461-463.
    • (1977) Science , vol.197 , Issue.4302 , pp. 461-463
    • Hamburger, A.W.1    Salmon, S.E.2
  • 30
    • 17144403478 scopus 로고    scopus 로고
    • Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer
    • Bapat, S.A.; Mali, A.M.; Koppikar, C.B.; Kurrey, N.K. Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer. Cancer Res., 2005, 65(8), 3025-3029.
    • (2005) Cancer Res. , vol.65 , Issue.8 , pp. 3025-3029
    • Bapat, S.A.1    Mali, A.M.2    Koppikar, C.B.3    Kurrey, N.K.4
  • 33
    • 70149124370 scopus 로고    scopus 로고
    • Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3
    • Gao, Q.; Geng, L.; Kvalheim, G.; Gaudernack, G.; Suo, Z. Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3. Ultrastruct. Pathol., 2009, 33(4), 175-181.
    • (2009) Ultrastruct. Pathol. , vol.33 , Issue.4 , pp. 175-181
    • Gao, Q.1    Geng, L.2    Kvalheim, G.3    Gaudernack, G.4    Suo, Z.5
  • 39
    • 33646560022 scopus 로고    scopus 로고
    • Systemic therapy for ovarian cancer: Current status and new treatments
    • Ozols, R.F. Systemic therapy for ovarian cancer: current status and new treatments. Semin. Oncol., 2006, 33(2 Suppl 6), S3-11.
    • (2006) Semin. Oncol. , vol.33 , Issue.2 SUPPL. 6
    • Ozols, R.F.1
  • 40
  • 42
    • 67349260705 scopus 로고    scopus 로고
    • Targeting cancer stem cells for more effective therapies: Taking out cancer's locomotive engine
    • Winquist, R.J.; Boucher, D.M.; Wood, M.; Furey, B.F. Targeting cancer stem cells for more effective therapies: Taking out cancer's locomotive engine. Biochem. Pharmacol., 2009, 78(4), 326-334.
    • (2009) Biochem. Pharmacol. , vol.78 , Issue.4 , pp. 326-334
    • Winquist, R.J.1    Boucher, D.M.2    Wood, M.3    Furey, B.F.4
  • 43
    • 33846239326 scopus 로고    scopus 로고
    • Recurrent ovarian cancer: Spectrum of imaging findings
    • Kwek, J.W.; Iyer, R.B. Recurrent ovarian cancer: Spectrum of imaging findings. AJR Am. J. Roentgenol., 2006, 187(1), 99-104.
    • (2006) AJR Am. J. Roentgenol. , vol.187 , Issue.1 , pp. 99-104
    • Kwek, J.W.1    Iyer, R.B.2
  • 44
    • 44649107292 scopus 로고    scopus 로고
    • Mechanisms of disease: Cancer stem cells--targeting the evil twin
    • Trumpp, A.; Wiestler, O.D. Mechanisms of disease: Cancer stem cells--targeting the evil twin. Nat. Clin. Pract. Oncol., 2008, 5(6), 337-347.
    • (2008) Nat. Clin. Pract. Oncol. , vol.5 , Issue.6 , pp. 337-347
    • Trumpp, A.1    Wiestler, O.D.2
  • 45
    • 52449091004 scopus 로고    scopus 로고
    • Drug-selected human lung cancer stem cells: Cytokine network, tumorigenic and metastatic properties
    • Levina, V.; Marrangoni, A.M.; DeMarco, R.; Gorelik, E.; Lokshin, A.E. Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties. PLoS ONE, 2008, 3(8), e3077.
    • (2008) PLoS ONE , vol.3 , Issue.8
    • Levina, V.1    Marrangoni, A.M.2    Demarco, R.3    Gorelik, E.4    Lokshin, A.E.5
  • 46
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • Gupta, P.B.; Onder, T.T.; Jiang, G.; Tao, K.; Kuperwasser, C.; Weinberg, R.A.; Lander, E.S. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell, 2009, 138(4), 645-659.
    • (2009) Cell , vol.138 , Issue.4 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3    Tao, K.4    Kuperwasser, C.5    Weinberg, R.A.6    Lander, E.S.7
  • 47
    • 51649112926 scopus 로고    scopus 로고
    • NFkappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells
    • Zhou, J.; Zhang, H.; Gu, P.; Bai, J.; Margolick, J.B.; Zhang, Y. NFkappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells. Breast Cancer Res. Treat., 2008, 111(3), 419-427.
    • (2008) Breast Cancer Res. Treat. , vol.111 , Issue.3 , pp. 419-427
    • Zhou, J.1    Zhang, H.2    Gu, P.3    Bai, J.4    Margolick, J.B.5    Zhang, Y.6
  • 48
    • 67349233539 scopus 로고    scopus 로고
    • Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model
    • Zhou, J.; Zhang, H.; Gu, P.; Margolick, J.B.; Yin, D.; Zhang, Y. Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model. Breast Cancer Res. Treat., 2009, 115(2), 269-277.
    • (2009) Breast Cancer Res. Treat. , vol.115 , Issue.2 , pp. 269-277
    • Zhou, J.1    Zhang, H.2    Gu, P.3    Margolick, J.B.4    Yin, D.5    Zhang, Y.6
  • 51
    • 73249117458 scopus 로고    scopus 로고
    • 7-(O)-Carboxymethyl daidzein conjugated to N-t-Boc-hexylenediamine: A novel compound capable of inducing cell death in epithelial ovarian cancer stem cells
    • Green, J.M.; Alvero, A.B.; Kohen, F.; Mor, G. 7-(O)-Carboxymethyl daidzein conjugated to N-t-Boc-hexylenediamine: A novel compound capable of inducing cell death in epithelial ovarian cancer stem cells. Cancer Biol. Ther., 2009, 8(18), 18.
    • (2009) Cancer Biol. Ther. , vol.8 , Issue.18 , pp. 18
    • Green, J.M.1    Alvero, A.B.2    Kohen, F.3    Mor, G.4
  • 52
    • 77950821063 scopus 로고    scopus 로고
    • Daidzein induces MCF-7 breast cancer cell apoptosis via the mitochondrial pathway
    • Jin, S.; Zhang, Q.Y.; Kang, X.M.; Wang, J.X.; Zhao, W.H. Daidzein induces MCF-7 breast cancer cell apoptosis via the mitochondrial pathway. Ann. Oncol., 2010, 21(2), 263-268.
    • (2010) Ann. Oncol. , vol.21 , Issue.2 , pp. 263-268
    • Jin, S.1    Zhang, Q.Y.2    Kang, X.M.3    Wang, J.X.4    Zhao, W.H.5
  • 54
    • 67649397334 scopus 로고    scopus 로고
    • Epigenetic gene regulation in stem cells and correlation to cancer
    • Mathews, L.A.; Crea, F.; Farrar, W.L. Epigenetic gene regulation in stem cells and correlation to cancer. Differentiation, 2009, 78(1), 1-17.
    • (2009) Differentiation , vol.78 , Issue.1 , pp. 1-17
    • Mathews, L.A.1    Crea, F.2    Farrar, W.L.3
  • 55
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • Feinberg, A.P.; Ohlsson, R.; Henikoff, S. The epigenetic progenitor origin of human cancer. Nat. Rev. Genet., 2006, 7(1), 21-33.
    • (2006) Nat. Rev. Genet. , vol.7 , Issue.1 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 56
    • 77950831242 scopus 로고    scopus 로고
    • Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype
    • Berry, N.B.; Bapat, S.A. Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype. J. Ovarian Res., 2008, 1, 8.
    • (2008) J. Ovarian Res. , vol.1 , pp. 8
    • Berry, N.B.1    Bapat, S.A.2
  • 57
    • 52949108784 scopus 로고    scopus 로고
    • And phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice
    • Guerrero-Bosagna, C.M.; Sabat, P.; Valdovinos, F.S.; Valladares, L.E.; Clark, S.J. Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice. BMC Physiol., 2008, 8, 17.
    • (2008) BMC Physiol. , vol.8 , pp. 17
    • Guerrero-Bosagna, C.M.1    Sabat, P.2    Valdovinos, F.S.3    Valladares, L.E.4    Epigenetic, C.J.S.5
  • 58
    • 26444451123 scopus 로고    scopus 로고
    • Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy
    • Fang, M.Z.; Chen, D.; Sun, Y.; Jin, Z.; Christman, J.K.; Yang, C.S. Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy. Clin. Cancer Res., 2005, 11(19 Pt 1), 7033-7041.
    • (2005) Clin. Cancer Res. , vol.11 , Issue.19 PRAT 1 , pp. 7033-7041
    • Fang, M.Z.1    Chen, D.2    Sun, Y.3    Jin, Z.4    Christman, J.K.5    Yang, C.S.6
  • 59
    • 33847688864 scopus 로고    scopus 로고
    • Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells
    • Choi, E.J.; Kim, T.; Lee, M.S. Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells. Life Sci., 2007, 80(15), 1403-1408.
    • (2007) Life Sci. , vol.80 , Issue.15 , pp. 1403-1408
    • Choi, E.J.1    Kim, T.2    Lee, M.S.3
  • 60
    • 33947302429 scopus 로고    scopus 로고
    • Genistein-induced apoptosis and autophagocytosis in ovarian cancer cells
    • DOI 10.1016/j.ygyno.2006.11.009, PII S0090825806009188
    • Gossner, G.; Choi, M.; Tan, L.; Fogoros, S.; Griffith, K.A.; Kuenker, M.; Liu, J.R. Genistein-induced apoptosis and autophagocytosis in ovarian cancer cells. Gynecol. Oncol., 2007, 105(1), 23-30. (Pubitemid 46441453)
    • (2007) Gynecologic Oncology , vol.105 , Issue.1 , pp. 23-30
    • Gossner, G.1    Choi, M.2    Tan, L.3    Fogoros, S.4    Griffith, K.A.5    Kuenker, M.6    Liu, J.R.7
  • 61
    • 67649518842 scopus 로고    scopus 로고
    • Modulation of CXCR4, CXCL12, and tumor cell invasion potential in vitro by phytochemicals
    • Hsu, E.L.; Chen, N.; Westbrook, A.; Wang, F.; Zhang, R.; Taylor, R.T.; Hankinson, O. Modulation of CXCR4, CXCL12, and tumor cell invasion potential in vitro by phytochemicals. J. Oncol., 2009, 2009, 491985.
    • (2009) J. Oncol. , vol.2009 , pp. 491985
    • Hsu, E.L.1    Chen, N.2    Westbrook, A.3    Wang, F.4    Zhang, R.5    Taylor, R.T.6    Hankinson, O.7
  • 62
    • 71549153495 scopus 로고    scopus 로고
    • Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways
    • Ouyang, G.; Yao, L.; Ruan, K.; Song, G.; Mao, Y.; Bao, S. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways. Cell Biol. Int., 2009, 33(12), 1237-1244.
    • (2009) Cell Biol. Int. , vol.33 , Issue.12 , pp. 1237-1244
    • Ouyang, G.1    Yao, L.2    Ruan, K.3    Song, G.4    Mao, Y.5    Bao, S.6
  • 63
  • 64
    • 44949133877 scopus 로고    scopus 로고
    • Genistein induces apoptosis in ovarian cancer cells via different molecular pathways depending on Breast Cancer Susceptibility gene-1 (BRCA1) status
    • Thasni, K.A.; Rojini, G.; Rakesh, S.N.; Ratheeshkumar, T.; Babu, M.S.; Srinivas, G.; Banerji, A.; Srinivas, P. Genistein induces apoptosis in ovarian cancer cells via different molecular pathways depending on Breast Cancer Susceptibility gene-1 (BRCA1) status. Eur. J. Pharmacol., 2008, 588(2-3), 158-164.
    • (2008) Eur. J. Pharmacol. , vol.588 , Issue.2-3 , pp. 158-164
    • Thasni, K.A.1    Rojini, G.2    Rakesh, S.N.3    Ratheeshkumar, T.4    Babu, M.S.5    Srinivas, G.6    Banerji, A.7    Srinivas, P.8
  • 65
    • 34548715144 scopus 로고    scopus 로고
    • Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development
    • Dolinoy, D.C.; Huang, D.; Jirtle, R.L. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc. Natl. Acad. Sci. USA, 2007, 104(32), 13056-13061.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , Issue.32 , pp. 13056-13061
    • Dolinoy, D.C.1    Huang, D.2    Jirtle, R.L.3
  • 66
    • 33645633542 scopus 로고    scopus 로고
    • Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome
    • Dolinoy, D.C.; Weidman, J.R.; Waterland, R.A.; Jirtle, R.L. Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ. Health Perspect., 2006, 114(4), 567-572.
    • (2006) Environ. Health Perspect. , vol.114 , Issue.4 , pp. 567-572
    • Dolinoy, D.C.1    Weidman, J.R.2    Waterland, R.A.3    Jirtle, R.L.4
  • 67
    • 39749140314 scopus 로고    scopus 로고
    • Modulation of gene methylation by genistein or lycopene in breast cancer cells
    • King-Batoon, A.; Leszczynska, J.M.; Klein, C.B. Modulation of gene methylation by genistein or lycopene in breast cancer cells. Environ. Mol. Mutagen, 2008, 49(1), 36-45.
    • (2008) Environ. Mol. Mutagen , vol.49 , Issue.1 , pp. 36-45
    • King-Batoon, A.1    Leszczynska, J.M.2    Klein, C.B.3
  • 69
    • 74549216395 scopus 로고    scopus 로고
    • Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer
    • Majid, S.; Dar, A.A.; Shahryari, V.; Hirata, H.; Ahmad, A.; Saini, S.; Tanaka, Y.; Dahiya, A.V.; Dahiya, R. Genistein reverses hypermethylation and induces active histone modifications in tumor suppressor gene B-Cell translocation gene 3 in prostate cancer. Cancer, 2010, 116(1), 66-76.
    • (2010) Cancer , vol.116 , Issue.1 , pp. 66-76
    • Majid, S.1    Dar, A.A.2    Shahryari, V.3    Hirata, H.4    Ahmad, A.5    Saini, S.6    Tanaka, Y.7    Dahiya, A.V.8    Dahiya, R.9
  • 70
    • 61649113446 scopus 로고    scopus 로고
    • Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women
    • Qin, W.; Zhu, W.; Shi, H.; Hewett, J.E.; Ruhlen, R.L.; MacDonald, R.S.; Rottinghaus, G.E.; Chen, Y.C.; Sauter, E.R. Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women. Nutr. Cancer, 2009, 61(2), 238-244.
    • (2009) Nutr. Cancer , vol.61 , Issue.2 , pp. 238-244
    • Qin, W.1    Zhu, W.2    Shi, H.3    Hewett, J.E.4    Ruhlen, R.L.5    MacDonald, R.S.6    Rottinghaus, G.E.7    Chen, Y.C.8    Sauter, E.R.9
  • 72
    • 0033031556 scopus 로고    scopus 로고
    • Silencing of the CD44 gene by CpG methylation in a human gastric carcinoma cell line
    • Sato, S.; Yokozaki, H.; Yasui, W.; Nikai, H.; Tahara, E. Silencing of the CD44 gene by CpG methylation in a human gastric carcinoma cell line. Jpn. J. Cancer Res., 1999, 90(5), 485-489.
    • (1999) Jpn. J. Cancer Res. , vol.90 , Issue.5 , pp. 485-489
    • Sato, S.1    Yokozaki, H.2    Yasui, W.3    Nikai, H.4    Tahara, E.5
  • 73
    • 0037301110 scopus 로고    scopus 로고
    • Hypermethylation-mediated regulation of CD44 gene expression in human neuroblastoma
    • Yan, P.; Muhlethaler, A.; Bourloud, K.B.; Beck, M.N.; Gross, N. Hypermethylation-mediated regulation of CD44 gene expression in human neuroblastoma. Genes Chromosomes Cancer, 2003, 36(2), 129-138.
    • (2003) Genes Chromosomes Cancer , vol.36 , Issue.2 , pp. 129-138
    • Yan, P.1    Muhlethaler, A.2    Bourloud, K.B.3    Beck, M.N.4    Gross, N.5
  • 77
    • 52049124277 scopus 로고    scopus 로고
    • Methylation of the prominin 1 TATA-less main promoters and tissue specificity of their transcript content
    • Pleshkan, V.V.; Vinogradova, T.V.; Sverdlov, E.D. Methylation of the prominin 1 TATA-less main promoters and tissue specificity of their transcript content. Biochim. Biophys. Acta., 2008, 1779(10), 599-605.
    • (2008) Biochim. Biophys. Acta. , vol.1779 , Issue.10 , pp. 599-605
    • Pleshkan, V.V.1    Vinogradova, T.V.2    Sverdlov, E.D.3
  • 83
    • 34548535326 scopus 로고    scopus 로고
    • DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets
    • Wu, Q.; Lothe, R.A.; Ahlquist, T.; Silins, I.; Trope, C.G.; Micci, F.; Nesland, J.M.; Suo, Z.; Lind, G.E. DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets. Mol. Cancer, 2007, 6, 45.
    • (2007) Mol. Cancer , vol.6 , pp. 45
    • Wu, Q.1    Lothe, R.A.2    Ahlquist, T.3    Silins, I.4    Trope, C.G.5    Micci, F.6    Nesland, J.M.7    Suo, Z.8    Lind, G.E.9
  • 85
    • 33747816812 scopus 로고    scopus 로고
    • Zinc finger tools: Custom DNAbinding domains for transcription factors and nucleases
    • Mandell, J.G.; Barbas, C.F., 3rd, Zinc Finger Tools: custom DNAbinding domains for transcription factors and nucleases. Nucleic Acids Res., 2006, 34, W516-523.
    • (2006) Nucleic Acids Res. , vol.34
    • Mandell, J.G.1    Barbas Iii, C.F.2
  • 86
    • 33646844482 scopus 로고    scopus 로고
    • Step into the groove: Engineered transcription factors as modulators of gene expression
    • Visser, A.E.; Verschure, P.J.; Gommans, W.M.; Haisma, H.J.; Rots, M.G. Step into the groove: engineered transcription factors as modulators of gene expression. Adv. Genet., 2006, 56, 131-161.
    • (2006) Adv. Genet. , vol.56 , pp. 131-161
    • Visser, A.E.1    Verschure, P.J.2    Gommans, W.M.3    Haisma, H.J.4    Rots, M.G.5
  • 87
    • 0036024956 scopus 로고    scopus 로고
    • The use of zinc finger peptides to study the role of specific factor binding sites in the chromatin environment
    • Segal, D.J. The use of zinc finger peptides to study the role of specific factor binding sites in the chromatin environment. Methods, 2002, 26(1), 76-83.
    • (2002) Methods , vol.26 , Issue.1 , pp. 76-83
    • Segal, D.J.1
  • 88
    • 33646839478 scopus 로고    scopus 로고
    • Step out of the groove: Epigenetic gene control systems and engineered transcription factors
    • Verschure, P.J.; Visser, A.E.; Rots, M.G. Step out of the groove: epigenetic gene control systems and engineered transcription factors. Adv. Genet., 2006, 56, 163-204.
    • (2006) Adv. Genet. , vol.56 , pp. 163-204
    • Verschure, P.J.1    Visser, A.E.2    Rots, M.G.3
  • 91
    • 0034721877 scopus 로고    scopus 로고
    • Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene
    • Zhang, L.; Spratt, S.K.; Liu, Q.; Johnstone, B.; Qi, H.; Raschke, E.E.; Jamieson, A.C.; Rebar, E.J.; Wolffe, A.P.; Case, C.C. Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene. J. Biol. Chem., 2000, 275(43), 33850-33860.
    • (2000) J. Biol. Chem. , vol.275 , Issue.43 , pp. 33850-33860
    • Zhang, L.1    Spratt, S.K.2    Liu, Q.3    Johnstone, B.4    Qi, H.5    Raschke, E.E.6    Jamieson, A.C.7    Rebar, E.J.8    Wolffe, A.P.9    Case, C.C.10
  • 93
    • 72949098057 scopus 로고    scopus 로고
    • Therapeutic microRNA strategies in human cancer
    • Li, C.; Feng, Y.; Coukos, G.; Zhang, L. Therapeutic microRNA strategies in human cancer. AAPS J., 2009, 11(4), 747-757.
    • (2009) AAPS J. , vol.11 , Issue.4 , pp. 747-757
    • Li, C.1    Feng, Y.2    Coukos, G.3    Zhang, L.4
  • 98
    • 50849104285 scopus 로고    scopus 로고
    • Mechanisms of microRNA deregulation in human cancer
    • Deng, S.; Calin, G.A.; Croce, C.M.; Coukos, G.; Zhang, L. Mechanisms of microRNA deregulation in human cancer. Cell Cycle, 2008, 7(17), 2643-2646.
    • (2008) Cell Cycle , vol.7 , Issue.17 , pp. 2643-2646
    • Deng, S.1    Calin, G.A.2    Croce, C.M.3    Coukos, G.4    Zhang, L.5
  • 102
    • 35548958882 scopus 로고    scopus 로고
    • Tumor cell dormancy: An NCI workshop report
    • Vessella, R.L.; Pantel, K.; Mohla, S. Tumor cell dormancy: an NCI workshop report. Cancer Biol. Ther., 2007, 6(9), 1496-1504.
    • (2007) Cancer Biol. Ther. , vol.6 , Issue.9 , pp. 1496-1504
    • Vessella, R.L.1    Pantel, K.2    Mohla, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.