Cystic fibrosis related diabetes mellitus - Diagnostic and management challenges

Current Diabetes Reviews

Volumn 6, Issue 1, 2010, Pages 9-16

  Lek, Ngee ^a   Acerini, Carlo L ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Continuous glucose monitoring systems; Cystic fibrosis; Cystic fibrosis related diabetes; Impaired glucose tolerance; Oral glucose tolerance test

Indexed keywords

ANTIDIABETIC AGENT; GLUCOSE; HEMOGLOBIN A1C; INSULIN; INSULIN GLARGINE; ISOPHANE INSULIN;

ADIPOCYTE; AGE DISTRIBUTION; BLOOD GLUCOSE MONITORING; BODY MASS; BODY WEIGHT; BOLUS INJECTION; CALORIC INTAKE; CELL FUNCTION; CELL INFILTRATION; CLINICAL TRIAL; CORTICOSTEROID THERAPY; CYSTIC FIBROSIS; CYSTIC FIBROSIS RELATED DIABETES MELLITUS; DIABETES MELLITUS; DIABETIC KETOACIDOSIS; DIET THERAPY; DISEASE ASSOCIATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; IMPAIRED GLUCOSE TOLERANCE; INCIDENCE; INFLAMMATION; INSULIN DEFICIENCY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN INFUSION; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TREATMENT; LIPID METABOLISM; LUNG FUNCTION; MICROANGIOPATHY; MORBIDITY; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; ONSET AGE; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET; PANCREAS ISLET CELL; PREVALENCE; PRIORITY JOURNAL; PROTEIN METABOLISM; RESPIRATORY TRACT INFECTION; REVIEW; SCREENING; STRESS; SURVIVAL RATE; WEIGHT REDUCTION;

ADOLESCENT; AGE FACTORS; BLOOD GLUCOSE; CHILD; CHILD, PRESCHOOL; CYSTIC FIBROSIS; DIABETES MELLITUS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INCIDENCE; MONITORING, PHYSIOLOGIC; PREDIABETIC STATE; PREVALENCE; YOUNG ADULT;

EID: 77950827682     PISSN: 15733998     EISSN: None     Source Type: Journal    
DOI: 10.2174/157339910790442600     Document Type: Review

References (29)

1. Cystic Fibrosis Foundation Patient Registry: Annual Data Report 2007; Bethesda, Maryland. Available from: http//:www.cff.org
2. Lanng S, Hansen A, Thorsteinsson B, Jerup J, Koch C. Glucose tolerance in patients with cystic fibrosis: five year prospective study. BMJ 1995; 311: 655-659
3. Moran A, Doherty L, Wang X, Thomas W. Abnormal glucose metabolism in cystic fibrosis. J Pediatr 1998; 133: 10-16 (Pubitemid 28323899)
4. Management of cystic fibrosis related diabetes mellitus. Report of the UK Cystic Fibrosis Trust Diabetes Working Group. June 2004.
5. Schwarzenberg SJ, Thomas W, Olsen TW, et al. Microvascular complications in cystic fibrosis-related diabetes. Diabetes Care 2007; 30: 1056-1061 (Pubitemid 46684624)
6. Figueroa V, Milla C, Parks EJ, Schwarzenberg SJ, Moran A. Abnormal lipid concentrations in cystic fibrosis. Am J Clin Nutr 2002; 75: 1005-1011 (Pubitemid 34547529)
7. Costa M, Potvin S, Berthiaume, et al. Diabetes: a major comorbidity of cystic fibrosis. Diabetes Metab 2005; 31; 221-232 (Pubitemid 40961519)
8. O'Riordan SMP, Robinson PD, Donaghue KC, Moran A. Management of cystic fibrosis-related diabetes. Pediatr Diabetes 2008; 9: 338-344
9. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 2000; 23: S4-S19.
10. Dobson L, Sheldon CD, Hattersley AT. Understanding cystic fibrosis related diabetes: best thought of as insulin deficiency? J R Soc Med 2004; 97: 26-35.
11. Dobson L, Hattersley AT, Tiley S, et al. Clinical improvement in cystic fibrosis with early insulin treatment. Arch Dis Child 2002; 87: 430-431 (Pubitemid 35252911)
12. Dobson L, Sheldon CD, Hattersley AT. Conventional measures underestimate glycaemia in cystic fibrosis patients. Diabet Med 2004; 21: 691-696 (Pubitemid 38916212)
13. Costa M, Potvin S, Hammana I, et al. Increased glucose excursion in cystic fibrosis and its association with a worse clinical status. J Cyst Fibros 2007; 6: 376-383 (Pubitemid 350028700)
14. Franzese A, Valerio G, Buono P, et al. Continuous glucose monitoring system in the screening of early glucose derangements in children and adolescents with cystic fibrosis. J Pediatr Endocrinol Metab 2008; 21: 109-116 (Pubitemid 351454563)
15. Elder DA, Wooldridge JL, Dolan LM, D'Alessio DA. Glucose tolerance, insulin secretion, and insulin sensitivity in children and adolescents with cystic fibrosis and no prior history of diabetes. J Pediatr 2007; 151: 653-658
16. Moreau F, Weiller MA, Rosner V, et al. Continuous glucose monitoring in cystic fibrosis patients according to the glucose tolerance. Horm Metab Res 2008; 40: 502-506
17. Jefferies C, Solomon M, Perlman K, et al. Continuous glucose monitoring in adolescents with cystic fibrosis. J Pediatr 2005; 147: 396-398 (Pubitemid 41345774)
18. Dobson L, Sheldon CD, Hattersley AT. Validation of interstitial fluid continuous glucose monitoring in cystic fibrosis. Diabetes Care 2003; 26: 1940-1941 (Pubitemid 36929150)
19. O'Riordan SM, Hindmarsh P, Hill NR, et al. Validation of continuous glucose monitoring in children and adolescents with cystic fibrosis - a prospective cohort study. Diabetes Care 2009; 32: 1020-1022
20. Onady GM, Stolfi A. Insulin and oral agents for managing cystic fibrosis-related diabetes. Cochrane Database Syst Rev 2005; CD004730.
21. Onady GM, Langdon LJ. Insulin versus oral agents in the management of cystic fibrosis related diabetes: a case based study. BMC Endocr Disord 2006; 6: 4.
22. Moran A, Phillips J, Milla C. Insulin and glucose excursion following premeal insulin lispro or repaglinide in cystic fibrosis-related diabetes. Diabetes Care 2001; 24: 1706-1710 (Pubitemid 33716470)
23. Rosenecker J, Eichler I, Barmeier H, von der Hardt H. Diabetes mellitus and cystic fibrosis: comparison of clinical parameters in patients treated with insulin versus oral glucose-lowering agents. Pediatr Pulmonol 2001; 32: 351-355 (Pubitemid 33015651)
24. Grover P, Thomas W, Moran A. Glargine versus NPH insulin in cystic fibrosis related diabetes. J Cyst Fibros 2008; 7: 134-136 (Pubitemid 351372762)
25. Sulli N, Bertasi S, Zullo S, Shashaj B. Use of continuous subcutaneous insulin infusion in patients with cystic fibrosis related diabetes: three case reports. J Cyst Fibros 2007; 6: 237-240 (Pubitemid 46567786)
26. Hardin DS, Rice J, Rice M, Rosenblatt R. Use of the insulin pump in treat cystic fibrosis related diabetes. J Cyst Fibros 2009; 8: 1748.
27. Bizzarri C, Lucidi V, Ciampalini P, et al. Clinical effects of early treatment with insulin glargine in patients with cystic fibrosis and impaired glucose tolerance. J Endocrinol Invest 2006; 29: RC1-4.
28. Mozzillo E, Franzese A, Valerio G, et al. One-year glargine treatment can improve the course of lung disease in children and adolescents with cystic fibrosis and early glucose derangements. Pediatric Diabetes 2009; 10: 162-167
29. Mohan K, Miller H, Burhan H, et al. Management of cystic fibrosis related diabetes: a survey of UK Cystic Fibrosis Centers. Pediatric Pulmonol 2008; 43: 642-647 (Pubitemid 351957281)