When the past challenges the present: are older antiepileptic drugs still the best choice in childhood absence epilepsy?

The Lancet Neurology

Volumn 9, Issue 5, 2010, Pages 457-459

  Arzimanoglou, Alexis ^a,b   Ryvlin, Philippe ^a,b   Perucca, Emilio ^c,d  

^a University Hospitals of Lyon   (France)

^b INSERM   (France)

^c Institute for Children and Adolescents with Epilepsy IDEE   (France)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ETHOSUXIMIDE; LAMOTRIGINE; VALPROIC ACID;

ABSENCE SEIZURE; CHILDHOOD ABSENCE EPILEPSY; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; DRUG EFFICACY; ELECTROENCEPHALOGRAM; EPILEPSY; HUMAN; LETTER; MONOTHERAPY; PRIORITY JOURNAL; SEIZURE;

ANTICONVULSANTS; CHILD; EPILEPSY, ABSENCE; ETHOSUXIMIDE; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; VALPROIC ACID;

EID: 77950827007     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(10)70089-2     Document Type: Letter

References (10)

1. Posner E.B., Mohamed K., and Marson A.G. A systematic review of treatment of typical absence seizures in children and adolescents with ethosuximide, sodium valproate or lamotrigine. Seizure 14 (2005) 117-122
2. Glauser T.A., Cnaan A., Shinnar S., et al. Ethosuximide, valproic acid and lamotrigine in childhood absence epilepsy. N Engl J Med 362 (2010) 790-799
3. Giannakodimos S., Ferrie C.D., and Panayiotopoulos C.P. Qualitative and quantitative abnormalities of breath counting during brief generalized 3 Hz spike and slow wave 'subclinical' discharges. Clin Electroencephalogr 26 (1995) 200-203
4. Wheless J.W., Clarke D.F., Arzimanoglou A., and Carpenter D. Treatment of pediatric epilepsy: European expert opinion, 2007. Epileptic Disord 9 (2007) 353-412
5. Wheless J.W., Clarke D.F., and Carpenter D. Treatment of pediatric epilepsy: expert opinion, 2005. J Child Neurol 20 suppl 1 (2005) S1-S56
6. Glauser T., Ben-Menachem E., Bourgeois B., et al. ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia 47 (2006) 1094-1120
7. Coppola G.G., Auricchio G., Federico R., et al. Lamotrigine vs valproic acid as first-line monotherapy in newly diagnosed typical absence seizures: an open-label, randomized, parallel-group study. Epilepsia 45 (2004) 1049-1053
8. Perucca E. An introduction to antiepileptic drugs. Epilepsia 46 suppl 4 (2005) 31-37
9. Hughes J.R. Absence seizures: a review of recent reports with new concepts. Epilepsy Behav 15 (2009) 404-412
10. Tomson T., and Battino D. Teratogenic effects of antiepileptic medications. Neurol Clin 27 (2009) 993-1002