메뉴 건너뛰기




Volumn 90, Issue 2, 2010, Pages 365-375

Palliative Chemotherapy for Pancreatic Malignancies

Author keywords

Chemotherapy; Management; Palliative; Pancreatic cancer

Indexed keywords

BEVACIZUMAB; CAPECITABINE; CETUXIMAB; CISPLATIN; DNA; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; EVEROLIMUS; FLUOROURACIL; FOLINIC ACID; GEFITINIB; GEMCITABINE; IRINOTECAN; MAMMALIAN TARGET OF RAPAMYCIN; OXALIPLATIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLACEBO; PROTEIN KINASE B; TAXANE DERIVATIVE; TRANSFORMING GROWTH FACTOR ALPHA; VASCULOTROPIN;

EID: 77950818346     PISSN: 00396109     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.suc.2009.12.005     Document Type: Review
Times cited : (7)

References (47)
  • 2
    • 77950803748 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network (NCCN) Available at:, Accessed November 3, 2009
    • National Comprehensive Cancer Network (NCCN) Available at:, Accessed November 3, 2009. http://www.nccn.org/professionals/physcian_gls/f_guidelines.asp.
  • 3
    • 42349093032 scopus 로고    scopus 로고
    • Meta-analysis of randomized trials: evaluation of benefit form gemcitabine-based combination chemotherapy applied in advanced pancreatic cancer
    • Heinemann V., Boeck S., Hinke A., et al. Meta-analysis of randomized trials: evaluation of benefit form gemcitabine-based combination chemotherapy applied in advanced pancreatic cancer. BMC Cancer 2008, 8:82.
    • (2008) BMC Cancer , vol.8 , pp. 82
    • Heinemann, V.1    Boeck, S.2    Hinke, A.3
  • 4
    • 38549113698 scopus 로고    scopus 로고
    • Chemotherapy for pancreatic cancer: from metastatic disease to adjuvant therapy
    • Wolff R. Chemotherapy for pancreatic cancer: from metastatic disease to adjuvant therapy. Cancer J 2007, 13(3):175-181.
    • (2007) Cancer J , vol.13 , Issue.3 , pp. 175-181
    • Wolff, R.1
  • 6
    • 0036137690 scopus 로고    scopus 로고
    • Phase II study of oral capecitabine on patients with advanced or metastatic pancreatic cancer
    • Cartwright T.H., Cohn A., Varkey J., et al. Phase II study of oral capecitabine on patients with advanced or metastatic pancreatic cancer. J Clin Oncol 2002, 20(1):160-164.
    • (2002) J Clin Oncol , vol.20 , Issue.1 , pp. 160-164
    • Cartwright, T.H.1    Cohn, A.2    Varkey, J.3
  • 7
    • 34247188535 scopus 로고    scopus 로고
    • Meta-analyses of chemotherapy for locally advanced and metastatic pancreatic cancer
    • Sultana A., Smith C.T., Cunningham D., et al. Meta-analyses of chemotherapy for locally advanced and metastatic pancreatic cancer. J Clin Oncol 2007, 25(18):2607-2615.
    • (2007) J Clin Oncol , vol.25 , Issue.18 , pp. 2607-2615
    • Sultana, A.1    Smith, C.T.2    Cunningham, D.3
  • 8
    • 33750106459 scopus 로고    scopus 로고
    • Chemotherapy and radiotherapy for inoperable advanced pancreatic cancer
    • CD002093
    • Yip D., Karapetis C., Strickland A., et al. Chemotherapy and radiotherapy for inoperable advanced pancreatic cancer. Cochrane Database Syst Rev 2006, (3). CD002093.
    • (2006) Cochrane Database Syst Rev , Issue.3
    • Yip, D.1    Karapetis, C.2    Strickland, A.3
  • 9
    • 33645051717 scopus 로고    scopus 로고
    • Multicenter phase I/II study using combination of gemcitabine and docetaxel in metastasized and unresectable, locally advanced pancreatic carcinoma
    • Ridwelski K., Fahlke J., Kuhn R., et al. Multicenter phase I/II study using combination of gemcitabine and docetaxel in metastasized and unresectable, locally advanced pancreatic carcinoma. Eur J Surg Oncol 2006, 32(3):297-302.
    • (2006) Eur J Surg Oncol , vol.32 , Issue.3 , pp. 297-302
    • Ridwelski, K.1    Fahlke, J.2    Kuhn, R.3
  • 10
    • 8644240004 scopus 로고    scopus 로고
    • Gemcitabine combined with docetaxel for the treatment of unresectable pancreatic carcinoma
    • Jacobs A.D., Otero H., Picozzi V.J., et al. Gemcitabine combined with docetaxel for the treatment of unresectable pancreatic carcinoma. Cancer Invest 2004, 22(4):505-514.
    • (2004) Cancer Invest , vol.22 , Issue.4 , pp. 505-514
    • Jacobs, A.D.1    Otero, H.2    Picozzi, V.J.3
  • 11
    • 0344305656 scopus 로고    scopus 로고
    • Phase II study of gemcitabine plus docetaxel in advanced pancreatic cancer: a Hoosier Oncology Group study
    • Schneider B.P., Ganjoo K.N., Seitz D.E., et al. Phase II study of gemcitabine plus docetaxel in advanced pancreatic cancer: a Hoosier Oncology Group study. Oncology 2003, 65(3):218-223.
    • (2003) Oncology , vol.65 , Issue.3 , pp. 218-223
    • Schneider, B.P.1    Ganjoo, K.N.2    Seitz, D.E.3
  • 13
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial
    • Burris H.A., Moore M.J., Andersen J., et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997, 15(6):2403-2413.
    • (1997) J Clin Oncol , vol.15 , Issue.6 , pp. 2403-2413
    • Burris, H.A.1    Moore, M.J.2    Andersen, J.3
  • 14
    • 0142121290 scopus 로고    scopus 로고
    • Randomized phase II comparison of dose intense gemcitabine: thirty minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma
    • Tempero M., Plunkett W., Van Haperen Ruiz, et al. Randomized phase II comparison of dose intense gemcitabine: thirty minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma. J Clin Oncol 2003, 21(18):3402-3408.
    • (2003) J Clin Oncol , vol.21 , Issue.18 , pp. 3402-3408
    • Tempero, M.1    Plunkett, W.2    Van Haperen, R.3
  • 15
    • 20644464360 scopus 로고    scopus 로고
    • Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer; results of a GERCOR and GISCAD phase III trial
    • Louvet C., Labianca R., Hammel P., et al. Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer; results of a GERCOR and GISCAD phase III trial. J Clin Oncol 2005, 23(15):3509-3516.
    • (2005) J Clin Oncol , vol.23 , Issue.15 , pp. 3509-3516
    • Louvet, C.1    Labianca, R.2    Hammel, P.3
  • 16
    • 68949114505 scopus 로고    scopus 로고
    • Phase III randomized study of gemcitabine and oxaliplatin versus gemcitabine (fixed dose rate infusion) compared with gemcitabine (30-minute infusion) in patients with pancreatic carcinoma E6201: a trial of the Eastern Cooperative Oncology Group
    • Poplin E., Feng Y., Berlin J., et al. Phase III randomized study of gemcitabine and oxaliplatin versus gemcitabine (fixed dose rate infusion) compared with gemcitabine (30-minute infusion) in patients with pancreatic carcinoma E6201: a trial of the Eastern Cooperative Oncology Group. J Clin Oncol 2009, 27(23):3778-3785.
    • (2009) J Clin Oncol , vol.27 , Issue.23 , pp. 3778-3785
    • Poplin, E.1    Feng, Y.2    Berlin, J.3
  • 18
    • 33748297529 scopus 로고    scopus 로고
    • A multicenter phase III trial comparing irinotecan-gemcitabine (IG) with gemcitabine (G) monotherapy as first-line treatment in patients with locally advanced or metastatic pancreatic cancer
    • Stathopoulos G.P., Syrigos K., Aravantinos G., et al. A multicenter phase III trial comparing irinotecan-gemcitabine (IG) with gemcitabine (G) monotherapy as first-line treatment in patients with locally advanced or metastatic pancreatic cancer. Br J Cancer 2006, 95(5):587-592.
    • (2006) Br J Cancer , vol.95 , Issue.5 , pp. 587-592
    • Stathopoulos, G.P.1    Syrigos, K.2    Aravantinos, G.3
  • 19
    • 33748445708 scopus 로고    scopus 로고
    • Randomized phase III trial of gemcitabine plus cisplatin compared with gemcitabine alone in advanced pancreatic cancer
    • Heinemann V., Quietzsh D., Gieseler F., et al. Randomized phase III trial of gemcitabine plus cisplatin compared with gemcitabine alone in advanced pancreatic cancer. J Clin Oncol 2006, 24(24):3946-3952.
    • (2006) J Clin Oncol , vol.24 , Issue.24 , pp. 3946-3952
    • Heinemann, V.1    Quietzsh, D.2    Gieseler, F.3
  • 20
    • 36049018883 scopus 로고    scopus 로고
    • Role of platinum agents in the management of advanced pancreatic cancer
    • Saif M.W., Kim R. Role of platinum agents in the management of advanced pancreatic cancer. Expert Opin Pharmacother 2007, 8(16):2719-2727.
    • (2007) Expert Opin Pharmacother , vol.8 , Issue.16 , pp. 2719-2727
    • Saif, M.W.1    Kim, R.2
  • 21
    • 34948888231 scopus 로고    scopus 로고
    • Increased survival using platinum analog combined with gemcitabine as compared to single agent gemcitabine in advanced pancreatic cancer: pooled analysis of two randomized trials the GERCOR/GISCAD intergroup study and a German multicenter study
    • Heinemann V., Labianca R., Hinke A., et al. Increased survival using platinum analog combined with gemcitabine as compared to single agent gemcitabine in advanced pancreatic cancer: pooled analysis of two randomized trials the GERCOR/GISCAD intergroup study and a German multicenter study. Ann Oncol 2007, 18(10):1652-1659.
    • (2007) Ann Oncol , vol.18 , Issue.10 , pp. 1652-1659
    • Heinemann, V.1    Labianca, R.2    Hinke, A.3
  • 22
    • 34250180939 scopus 로고    scopus 로고
    • Gemcitabine plus capecitabine compared with gemcitabine alone in advanced pancreatic cancer. A randomized multicenter, phase III trial of the Swiss Group for Clinical Cancer research and the Central European Cooperative Oncology Group
    • Hermann R., Bodoky G., Ruhstaller B., et al. Gemcitabine plus capecitabine compared with gemcitabine alone in advanced pancreatic cancer. A randomized multicenter, phase III trial of the Swiss Group for Clinical Cancer research and the Central European Cooperative Oncology Group. J Clin Oncol 2007, 25:2212-2217.
    • (2007) J Clin Oncol , vol.25 , pp. 2212-2217
    • Hermann, R.1    Bodoky, G.2    Ruhstaller, B.3
  • 23
    • 29344476191 scopus 로고    scopus 로고
    • Phase III randomized comparison of gemcitabine (GEM) versus gemcitabine plus capecitabine (GEM-CAP) in patients with advanced pancreatic cancer
    • Cunningham D., Chau I., Stocken D., et al. Phase III randomized comparison of gemcitabine (GEM) versus gemcitabine plus capecitabine (GEM-CAP) in patients with advanced pancreatic cancer. Eur J Cancer Suppl 2005, 3:4.
    • (2005) Eur J Cancer Suppl , vol.3 , pp. 4
    • Cunningham, D.1    Chau, I.2    Stocken, D.3
  • 24
    • 45749089796 scopus 로고    scopus 로고
    • Metastatic pancreatic cancer 2008: is the glass less empty?
    • Nieto J., Grossbard M., Kozuch P. Metastatic pancreatic cancer 2008: is the glass less empty?. Oncologist 2008, 13:562-576.
    • (2008) Oncologist , vol.13 , pp. 562-576
    • Nieto, J.1    Grossbard, M.2    Kozuch, P.3
  • 25
    • 67649386620 scopus 로고    scopus 로고
    • Emerging drugs in the treatment of pancreatic cancer
    • Mahalingam D., Kelly K., Swords R., et al. Emerging drugs in the treatment of pancreatic cancer. Expert Opin Emerg Drugs 2009, 14(2):311-328.
    • (2009) Expert Opin Emerg Drugs , vol.14 , Issue.2 , pp. 311-328
    • Mahalingam, D.1    Kelly, K.2    Swords, R.3
  • 26
    • 56249104160 scopus 로고    scopus 로고
    • Challenges in developing targeted therapies for pancreatic adnenocarcinoma
    • Mahalingam D., Giles F. Challenges in developing targeted therapies for pancreatic adnenocarcinoma. Expert Opin Ther Targets 2008, 12(11):1389-1401.
    • (2008) Expert Opin Ther Targets , vol.12 , Issue.11 , pp. 1389-1401
    • Mahalingam, D.1    Giles, F.2
  • 28
    • 34249933404 scopus 로고    scopus 로고
    • Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore M.J., Goldstein D., Hamm J., et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2007, 25(15):1960-1966.
    • (2007) J Clin Oncol , vol.25 , Issue.15 , pp. 1960-1966
    • Moore, M.J.1    Goldstein, D.2    Hamm, J.3
  • 29
    • 38049041406 scopus 로고    scopus 로고
    • Erlotinib/gemcitabine for first-line treatment of locally advanced or metastatic adenocarcinoma of the pancreas
    • Senderowicz A., Johnson J., Sridhara R., et al. Erlotinib/gemcitabine for first-line treatment of locally advanced or metastatic adenocarcinoma of the pancreas. Oncology (Williston Park). (FDA Approval Summary) 2007, 21(14):1696-1706.
    • (2007) Oncology (Williston Park). (FDA Approval Summary) , vol.21 , Issue.14 , pp. 1696-1706
    • Senderowicz, A.1    Johnson, J.2    Sridhara, R.3
  • 30
    • 77950789069 scopus 로고    scopus 로고
    • Erlotinib as a single agent therapy in patients with advanced pancreatic cancer. Presented at the ,ASCO GI Cancer Symposium. Orlando (FL), January 19-21, 2007.
    • Epelbaum R, Schnaider J, Gluzman A, et al. Erlotinib as a single agent therapy in patients with advanced pancreatic cancer. Presented at the 2007 ASCO GI Cancer Symposium. Orlando (FL), January 19-21, 2007.
    • (2007)
    • Epelbaum, R.1    Schnaider, J.2    Gluzman, A.3    et al4
  • 31
    • 51749121596 scopus 로고    scopus 로고
    • Targeted therapies for pancreatic cancer
    • Danovi S.A., Wong H.H., Lemoine N.R. Targeted therapies for pancreatic cancer. Br Med Bull 2008, 87:97-130.
    • (2008) Br Med Bull , vol.87 , pp. 97-130
    • Danovi, S.A.1    Wong, H.H.2    Lemoine, N.R.3
  • 32
    • 35548941394 scopus 로고    scopus 로고
    • Cancer and Leukemia group B A Double blind, placebo controlled randomized phase III trial of gemcitabine (G) plus bevacizumab (B) versus gemcitabine plus placebo (P) in pts with advanced pancreatic cancer (PC); a preliminary analysis of CALGB
    • (meeting abstracts) [abstract 4508], s
    • Kindler H.L., Niedzwiecki D., Hollis D., et al. Cancer and Leukemia group B A Double blind, placebo controlled randomized phase III trial of gemcitabine (G) plus bevacizumab (B) versus gemcitabine plus placebo (P) in pts with advanced pancreatic cancer (PC); a preliminary analysis of CALGB. J Clin Oncol 2007, 25(18s). (meeting abstracts) [abstract 4508].
    • (2007) J Clin Oncol , vol.25 , Issue.18
    • Kindler, H.L.1    Niedzwiecki, D.2    Hollis, D.3
  • 33
    • 32944478346 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer
    • Kindler H.L., Friberg G., Singh D.A., et al. Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer. J Clin Oncol 2005, 23:8033-8040.
    • (2005) J Clin Oncol , vol.23 , pp. 8033-8040
    • Kindler, H.L.1    Friberg, G.2    Singh, D.A.3
  • 34
    • 65549150854 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in metastatic pancreatic cancer
    • Van Cutsem E., Ververnne W.L., Bennouna J., et al. Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in metastatic pancreatic cancer. J Clin Oncol 2009, 27(13):2231-2237.
    • (2009) J Clin Oncol , vol.27 , Issue.13 , pp. 2231-2237
    • Van Cutsem, E.1    Ververnne, W.L.2    Bennouna, J.3
  • 35
    • 48949095510 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo (P) controlled, multicenter phase III trial to evaluate the efficacy and safety of adding bevacizumab (B) to erlotinib (E) and gemcitabine (G) in patients (pts) with metastatic pancreatic cancer [abstract 4507]
    • 2008 ASCO Annual Meeting Proceedings,
    • Vervenne W., Bennouna Y., Humblet S., et al. A randomized, double-blind, placebo (P) controlled, multicenter phase III trial to evaluate the efficacy and safety of adding bevacizumab (B) to erlotinib (E) and gemcitabine (G) in patients (pts) with metastatic pancreatic cancer [abstract 4507]. J Clin Oncol 2008, 26(15S). 2008 ASCO Annual Meeting Proceedings.
    • (2008) J Clin Oncol , vol.26 , Issue.15
    • Vervenne, W.1    Bennouna, Y.2    Humblet, S.3
  • 36
    • 39149112958 scopus 로고    scopus 로고
    • Sorafenib plus gemcitabine for advanced pancreatic cancer (PC): a phase II trial of the University of Chicago Phase II Consortium. 2007 ASCO Annual Meeting Proceedings Part I [abstract 4608]
    • Wallace J.A., Locker G., Nattam S., et al. Sorafenib plus gemcitabine for advanced pancreatic cancer (PC): a phase II trial of the University of Chicago Phase II Consortium. 2007 ASCO Annual Meeting Proceedings Part I [abstract 4608]. J Clin Oncol 2007, 25(18S (Suppl 20)).
    • (2007) J Clin Oncol , vol.25 , Issue.20 SUPPL
    • Wallace, J.A.1    Locker, G.2    Nattam, S.3
  • 37
    • 67649377832 scopus 로고    scopus 로고
    • Phase I dose findings study of sunitinib (SU) in combination with gemcitabine (G) in patients (pts) with advanced solid tumors [abstract 14522]
    • Michaelson M.D., Schwarzberg A., Ryan D.P., et al. Phase I dose findings study of sunitinib (SU) in combination with gemcitabine (G) in patients (pts) with advanced solid tumors [abstract 14522]. Clin Oncol 2008, 26(Suppl 20).
    • (2008) Clin Oncol , vol.26 , Issue.20 SUPPL.
    • Michaelson, M.D.1    Schwarzberg, A.2    Ryan, D.P.3
  • 38
    • 33750903161 scopus 로고    scopus 로고
    • A randomized phase II study of bevacizumab (B) and gemcitabine (G) plus cetuximab (C) or erlotinib (E) in patients (pts) with advanced pancreatic cancer (PC) [abstract 4502]. ASCO Annual Meeting Proceedings
    • S
    • Kindler H.L., Bylow K.A., Hoschester G., et al. A randomized phase II study of bevacizumab (B) and gemcitabine (G) plus cetuximab (C) or erlotinib (E) in patients (pts) with advanced pancreatic cancer (PC) [abstract 4502]. ASCO Annual Meeting Proceedings. J Clin Oncol 2006, 26(15S).
    • (2006) J Clin Oncol , vol.26 , Issue.15
    • Kindler, H.L.1    Bylow, K.A.2    Hoschester, G.3
  • 39
    • 0037280222 scopus 로고    scopus 로고
    • Metastatic pancreatic cancer; emerging strategies in chemotherapy and palliative care
    • El Kamar F., Grossbard M., Kozuch P. Metastatic pancreatic cancer; emerging strategies in chemotherapy and palliative care. Oncologist 2003, 8:18-34.
    • (2003) Oncologist , vol.8 , pp. 18-34
    • El Kamar, F.1    Grossbard, M.2    Kozuch, P.3
  • 40
    • 58249085318 scopus 로고    scopus 로고
    • Oral mTOR Inhibitor Everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer
    • Wolpin B., Hezel A., Abrams T., et al. Oral mTOR Inhibitor Everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer. J Clin Oncol 2009, 27(2):193-198.
    • (2009) J Clin Oncol , vol.27 , Issue.2 , pp. 193-198
    • Wolpin, B.1    Hezel, A.2    Abrams, T.3
  • 41
    • 77950810103 scopus 로고    scopus 로고
    • Inhibition of mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: the results of two prospective studies [abstract 4621]. ASCO Annual Meeting Proceedings
    • S
    • Javle M.M., Xiong H., Reddy S., et al. Inhibition of mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: the results of two prospective studies [abstract 4621]. ASCO Annual Meeting Proceedings. J Clin Oncol 2009, 27(15S).
    • (2009) J Clin Oncol , vol.27 , Issue.15
    • Javle, M.M.1    Xiong, H.2    Reddy, S.3
  • 42
    • 36549083856 scopus 로고    scopus 로고
    • Phase III study of gemcitabine (G) plus cetuximab (C) versus gemcitabine in patients (pts) with locally advanced or metastatic pancreatic adenocarcinoma (PC): SWOG S0205 study [abstract LBA4509]
    • Annual Meeting Proceedings, S
    • Phillip P.A., Benedetti C., Fenoglio-Preiser M., et al. Phase III study of gemcitabine (G) plus cetuximab (C) versus gemcitabine in patients (pts) with locally advanced or metastatic pancreatic adenocarcinoma (PC): SWOG S0205 study [abstract LBA4509]. J Clin Oncol 2007, 25(18S). Annual Meeting Proceedings.
    • (2007) J Clin Oncol , vol.25 , Issue.18
    • Phillip, P.A.1    Benedetti, C.2    Fenoglio-Preiser, M.3
  • 44
    • 54949112461 scopus 로고    scopus 로고
    • Second-line therapy for gemcitabine-refractory pancreatic cancer: is there a standard?
    • Almhanna K., Kim R. Second-line therapy for gemcitabine-refractory pancreatic cancer: is there a standard?. Oncology 2008, 22(10):1176-1183.
    • (2008) Oncology , vol.22 , Issue.10 , pp. 1176-1183
    • Almhanna, K.1    Kim, R.2
  • 45
    • 63849329062 scopus 로고    scopus 로고
    • Second-line therapy in refractory pancreatic cancer: results of a phase II study
    • Pelzer U., Stieler J., Roll L., et al. Second-line therapy in refractory pancreatic cancer: results of a phase II study. Onkologie 2009, 32(3):99-102.
    • (2009) Onkologie , vol.32 , Issue.3 , pp. 99-102
    • Pelzer, U.1    Stieler, J.2    Roll, L.3
  • 46
    • 52249103952 scopus 로고    scopus 로고
    • Weekly docetaxel as salvage therapy in patients with gemcitabine refractory metastatic pancreatic cancer
    • Cereda S., Reni M. Weekly docetaxel as salvage therapy in patients with gemcitabine refractory metastatic pancreatic cancer. J Chemother 2008, 20(4):509-512.
    • (2008) J Chemother , vol.20 , Issue.4 , pp. 509-512
    • Cereda, S.1    Reni, M.2
  • 47
    • 37849031303 scopus 로고    scopus 로고
    • Excess toxicity associated with docetaxel and irinotecan in patients with metastatic gemcitabine-refractory pancreatic cancer: results of a phase II study
    • Ko A.H., Dito E., Schillinger B., et al. Excess toxicity associated with docetaxel and irinotecan in patients with metastatic gemcitabine-refractory pancreatic cancer: results of a phase II study. Cancer Invest 2008, 26(1):47-52.
    • (2008) Cancer Invest , vol.26 , Issue.1 , pp. 47-52
    • Ko, A.H.1    Dito, E.2    Schillinger, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.