Treatment with HELP-apheresis in patients suffering from sudden sensorineural hearing loss: A prospective, randomized, controlled study

Laryngoscope

Volumn 120, Issue 4, 2010, Pages 800-807

  Bianchin, Giovanni ^a   Russi, Gianpaolo ^a   Romano, Nicola ^a   Fioravanti, Paola ^a  

^a S MARIA NUOVA HOSPITAL   (Italy)

Author keywords

Fibrinogen; Hearing recovery; HELP apheresis; LDL cholesterol; Sudden hearing loss

Indexed keywords

DEXAMETHASONE; FIBRINOGEN; GLYCEROL; HELP APHERESIS; LOW DENSITY LIPOPROTEIN CHOLESTEROL; UNCLASSIFIED DRUG;

ADULT; AGED; APHERESIS; ARTICLE; BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVALESCENCE; FOLLOW UP; HEPARIN INDUCED LDL AND FIBRINOGEN PRECIPITATION APHERESIS; HUMAN; MAJOR CLINICAL STUDY; PATIENT ASSESSMENT; PERCEPTION DEAFNESS; PLASMAPHERESIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; AGED; AGED, 80 AND OVER; AUDIOMETRY, PURE-TONE; AUDITORY THRESHOLD; BLOOD COMPONENT REMOVAL; CHOLESTEROL, LDL; FIBRINOGEN; FOLLOW-UP STUDIES; HEARING LOSS, SUDDEN; HUMANS; MIDDLE AGED; PROSPECTIVE STUDIES; RECOVERY OF FUNCTION; TREATMENT OUTCOME;

EID: 77950817939     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1002/lary.20835     Document Type: Article

References (21)

1. Lazarini PR, Camargo ACK. Idiophatic sudden sensorineural hearing loss: etiopathogenic aspects. Rev Bras Otorrinolaringol 2006;72:554-561. (Pubitemid 44696250)
2. Capaccio P, Ottaviani F, Cuccarini V, et al. Genetic and acquired prothrombotic risk factors and sudden hearing loss. Laryngoscope 2007;117:547-551. (Pubitemid 46407770)
3. Marcucci R, Alessandrello Liotta A, Cellai AP, et al. Cardiovascular and thrombophilic risk factors for idiopathic sudden sensorineural hearing loss. J Thromb Haemost 2005;3:929-934. (Pubitemid 41632821)
4. Sauvaget E, Kici S, Petelle B, et al. Vertebrobasilar occlusive disorders presenting as sudden sensorineural hearing loss. Laryngoscope 2004;114:327-332. (Pubitemid 38182633)
5. Castro Junior NP, Almeida CI, Campos CA. Sudden sensorineural hearing loss and vertigo associated with arterial occlusive disease: three case reports and literature review. Sao Paulo Med J 2007;125:191-195.
6. Vazquez R, Solanellas J, Alfageme I, et al. Mitral valve prolapse and sudden deafness. Int J Cardiol 2008;124: 370-371. (Pubitemid 351305363)
7. Mattox DE, Simmons SB. Natural history of sudden hearing loss. Ann Otol Rhinol Laryngol 1977;86:463-480.
8. Loughan S. Management of sudden sensorineural hearing loss: a consultant survey J Olaryngol Otol 2000;114:837-839.
9. Schuff-Werner P. Increased red blood cell adhesiveness/aggregation owing to fibrinogen elevation in hypercholesterolaemic patients and the rationale of fibrinogen-lowering by LDL apheresis. Eur J Clin Inv 2004;34:378-379. (Pubitemid 38748079)
10. Balletshofer BM, Stock J, Rittig K, et al. Acute effect of rheopheresis on periferal endothelial dysfunction in patients suffering from sudden hearing loss. Ther Apher Dial 2005;9:385-390. (Pubitemid 43943058)
11. Ramunni A, Quaranta N, Saliani MT, Fallacara RA, Ria R, Ranieri G. Does a reduction of adhesion molecules by LDL-apheresis have a role in the treatment of sudden hearing loss? Ther Apher Dial 2006;10:282-286. (Pubitemid 43979301)
12. Ullrich H, Kleinjung T, Steffens T, Jacob P, Schmitz G, Strutz J. Improved Treatment of Sudden Hearing Loss by Specific Fibrinogen Apheresis. J Clin Apheresis 2004;19: 71-78. (Pubitemid 39006611)
13. Jaeger BR. Evidence for maximal treatment of atherosclerosis: drastic reduction of cholesterol and fibrinogen restores vascular homeostasis. Ther Apher 2001;5:207-211.
14. Suckfull M. Fibrinogen and LDL apheresis in treatment of sudden hearing loss: a randomised multicentre trial. Lancet 2002;360:1811-1817. (Pubitemid 35449418)
15. Nakashima T, Yanagita Y, Ohno J, Kanzaki T, Shitara T. Comparative study on sudden deafness by two nationwide epidemiological surveys in Japan. Acta Otolaryngol Stockh 1994;514:14-16. (Pubitemid 24201650)
16. Bosatra A, Destefani GB. The idiopathic sudden deafness. A clinical study. Acta Otolaryngol Suppl 1961;169:1-62.
17. Otto C, Schwandt P, Richter WO. Haemorheology in defined dyslipoproteinemias with elevated serum triglyceride concentrations. Atherosclerosis 1995;125:s117.
18. Slyper A, Le A, Jurva J, Gutterman D. The influence of lipoproteins on blood-whole viscosity at multiple shear rates. Metab Clin Exp 2005;54:764-768. (Pubitemid 40725325)
19. Assayag EB, Bornstein N, Shapira I, et al. Inflammationsensitive proteins and erythrocyte aggregation in atherothrombosis. Int J Cardiol 2005;98:271-276. (Pubitemid 40431174)
20. Kirschkamp T, Schimd-Schonbein H, Weinberger A, Smeets R. Effects of fibrinogen and alpha2-macroglobulin and their apheretic elimination on general blood rheology and rheological characteristics of red blood cell aggregates. Ther Apher Dial 2008;12:360-367.
21. Mosges R, Koberlein J. Rheopheresis for idiopathic sudden hearing loss: results from a large prospective, multicenter, randomized, controlled clinical trial. Eur Arch Otorhinolaryngol 2009;266:943-953.