Are there differences in brain morphometry between twins and unrelated singletons? A pediatric MRI study

Genes, Brain and Behavior

Volumn 9, Issue 3, 2010, Pages 288-295

  Ordaz, S J ^a,b   Lenroot, R K ^a,c   Wallace, G L ^a   Clasen, L S ^a   Blumenthal, J D ^a   Schmitt, J E ^d   Giedd, J N ^a,c  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Adolescent; Brain; Child; Singleton; Twin

Indexed keywords

ADOLESCENT; AGE; ARTICLE; BRAIN; BRAIN DEVELOPMENT; BRAIN SIZE; BRAIN VENTRICLE; CHILD; CONTROLLED STUDY; CORPUS CALLOSUM; FEMALE; GRAY MATTER; HERITABILITY; HUMAN; INFANT; MALE; MORPHOMETRICS; NEUROANATOMY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; TWINS; WHITE MATTER;

ADOLESCENT; BRAIN; BRAIN MAPPING; CHILD; CHILD DEVELOPMENT; CHILD, PRESCHOOL; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; ORGAN SIZE; REGRESSION ANALYSIS; TWINS; YOUNG ADULT;

EID: 77950800300     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2009.00558.x     Document Type: Article

References (53)

1. Baare, W.F., Hulshoff Pol, H.E., Boomsma, D.I., Posthuma, D., de Geus, E.J., Schnack, H.G., van Haren, N.E., van Oel, C.J. & Kahn, R.S. (2001) Quantitative genetic modeling of variation in human brain morphology. Cereb Cortex 11, 816 824.
2. Benjamini, Y. & Hochberg, Y. (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B (Methodol) 57, 289 300.
3. Brun, C.C., Lepore, N., Pennec, X., Lee, A.D., Barysheva, M., Madsen, S.K., Avedissian, C., Chou, Y.Y., de Zubicaray, G.I., McMahon, K.L., Wright, M.J., Toga, A.W. & Thompson, P.M. (2009) Mapping the regional influence of genetics on brain structure variability - a tensor-based morphometry study. Neuroimage 48, 37 49.
4. Buckler, J.M. & Green, M. (2004) A comparison of the early growth of twins and singletons. Ann Hum Biol 31, 311 332.
5. Christensen, K., Petersen, I., Skytthe, A., Herskind, A.M., McGue, M. & Bingley, P. (2006) Comparison of academic performance of twins and singletons in adolescence: follow-up study. BMJ 333, 1095 1099.
6. Cohen, J. (1992) A power primer. Psychol Bull 112, 155 159.
7. Collins, D.L., Neelin, P., Peters, T.M. & Evans, A.C. (1994) Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr 18, 192 205.
8. Collins, D.L., Holmes, C.J., Peters, T.M. & Evans, A.C. (1995) Automatic 3-D model-based neuroanatomical segmentation. Hum Brain Mapp 3, 190 208.
9. Deary, I.J., Pattie, A., Wilson, V. & Whalley, L.J. (2005) The cognitive cost of being a twin: two whole-population surveys. Twin Res Hum Genet 8, 376 383.
10. Denckla, M.B. (1985) Revised physical and neurological examination for subtle signs. Psychopharmacol Bull 21, 773 800.
11. Drillien, C.M. (1961) The incidence of mental and physical handicaps in school-age children of very low birth weight. Pediatrics 27, 452 464.
12. Faul, F., Erdfelder, E., Lang, A.-G. & Buchner, A. (2007) G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39, 175 191.
13. Giedd, J.N., Blumenthal, J., Jeffries, N.O., Rajapakse, J.C., Vaituzis, A.C., Liu, H., Berry, Y.C., Tobin, M., Nelson, J. & Castellanos, F.X. (1999) Development of the human corpus callosum during childhood and adolescence: a longitudinal MRI study. Prog Neuropsychopharmacol Biol Psychiatry 23, 571 588. (Pubitemid 29268403)
14. Giedd, J.N., Lalonde, F.M., Celano, M.J., White, S.L., Wallace, G.L., Lee, N.R. & Lenroot, R.K. (2009) Anatomical brain magnetic resonance imaging of typically developing children and adolescents. J Am Acad Child Adolesc Psychiatry 48, 465 470.
15. Glinianaia, S.V., Skjaerven, R. & Magnus, P. (2000) Birthweight percentiles by gestational age in multiple births. A population-based study of Norwegian twins and triplets. Acta Obstet Gynecol Scand 79, 450 458.
16. Hollingshead, A.B. & Redlich, F.C. (1958) Social Class and Mental Illness; A Community Study. Wiley
17. Hollingshead, A.B. & Redlich, F.C. (2007) Social class and mental illness: a community study. Am J Public Health 97, 1756 1757.
18. Hulshoff Pol, H.E., Posthuma, D., Baare, W.F., De Geus, E.J., Schnack, H.G., van Haren, N.E., van Oel, C.J., Kahn, R.S. & Boomsma, D.I. (2002) Twin-singleton differences in brain structure using structural equation modelling. Brain 125, 384 390.
19. Hulshoff Pol, H.E., Schnack, H.G., Posthuma, D., Mandl, R.C., Baare, W.F., van Oel, C., van Haren, N.E., Collins, D.L., Evans, A.C., Amunts, K., Burgel, U., Zilles, K., de Geus, E., Boomsma, D.I. & Kahn, R.S. (2006) Genetic contributions to human brain morphology and intelligence. J Neurosci 26, 10235 10242.
20. Keppel, G. & Wickens, T.D. (2004) Design and Analysis: A Researcher′s Handbook, 4th edn. Pearson Education, Inc., Upper Saddle River, N.J.
21. Lenroot, R.K., Gogtay, N., Greenstein, D.K., Wells, E.M., Wallace, G.L., Clasen, L.S., Blumenthal, J.D., Lerch, J., Zijdenbos, A.P., Evans, A.C., Thompson, P.M. & Giedd, J.N. (2007) Sexual dimorphism of brain developmental trajectories during childhood and adolescence. Neuroimage 36, 1065 1073.
22. Lenroot, R.K., Schmitt, J.E., Ordaz, S.J., Wallace, G.L., Neale, M.C., Lerch, J.P., Kendler, K.S., Evans, A.C. & Giedd, J.N. (2009) Differences in genetic and environmental influences on the human cerebral cortex associated with development during childhood and adolescence. Hum Brain Mapp 30, 163 174.
23. Liu, Y.C. & Blair, E.M. (2002) Predicted birthweight for singletons and twins. Twin Res 5, 529 537.
24. Lu, L.H., Dapretto, M., O′Hare, E.D., Kan, E., McCourt, S.T., Thompson, P.M., Toga, A.W., Bookheimer, S.Y. & Sowell, E.R. (2009) Relationships between brain activation and brain structure in normally developing children. Cereb Cortex 19, 2595 2604.
25. McClearn, G.E., Johansson, B., Berg, S., Pedersen, N.L., Ahern, F., Petrill, S.A. & Plomin, R. (1997) Substantial genetic influence on cognitive abilities in twins 80 or more years old. Science 276, 1560 1563.
26. Mehrotra, S.N. & Maxwell, J. (1949) The intelligence of twins. A comparative study of eleven-year-old twins. Popul Stud 3, 295 302.
27. Nagy, P.S. (2003) Spontaneous rupture of the uterus caused by placenta percreta at 28 weeks of twin pregnancy. Eur J Obstet Gynecol Reprod Biol 111, 207 209.
28. Parker, J., Mitchell, A., Kalpakidou, A., Walshe, M., Jung, H.Y., Nosarti, C., Santosh, P., Rifkin, L., Wyatt, J., Murray, R.M. & Allin, M. (2008) Cerebellar growth and behavioural & neuropsychological outcome in preterm adolescents. Brain 131, 1344 1351.
29. Paus, T., Zijdenbos, A., Worsley, K., Collins, D.L., Blumenthal, J., Giedd, J.N., Rapoport, J.L. & Evans, A.C. (1999) Structural maturation of neural pathways in children and adolescents: in vivo study. Science 283, 1908 1911.
30. Peper, J.S., Schnack, H.G., Brouwer, R.M., Van Baal, G.C., Pjetri, E., Szekely, E., van Leeuwen, M., van den Berg, S.M., Collins, D.L., Evans, A.C., Boomsma, D.I., Kahn, R.S. & Hulshoff Pol, H.E. (2009) Heritability of regional and global brain structure at the onset of puberty: a magnetic resonance imaging study in 9-year-old twin pairs. Hum Brain Mapp 30, 2184 2196.
31. Peterson, B.S., Vohr, B., Staib, L.H., Cannistraci, C.J., Dolberg, A., Schneider, K.C., Katz, K.H., Westerveld, M., Sparrow, S., Anderson, A.W., Duncan, C.C., Makuch, R.W., Gore, J.C. & Ment, L.R. (2000) Regional brain volume abnormalities and long-term cognitive outcome in preterm infants. JAMA 284, 1939 1947.
32. Plomin, R. & Kosslyn, S.M. (2001) Genes, brain and cognition. Nat Neurosci 4, 1153 1154.
33. Plomin, R., Pedersen, N.L., Lichtenstein, P. & McClearn, G.E. (1994) Variability and stability in cognitive abilities are largely genetic later in life. Behav Genet 24, 207 215.
34. Posthuma, D., De Geus, E.J., Bleichrodt, N. & Boomsma, D.I. (2000) Twin-singleton differences in intelligence? Twin Res 3, 83 87.
35. Powers, W.F. & Kiely, J.L. (1994) The risks confronting twins: a national perspective. Am J Obstet Gynecol 170, 456 461.
36. Rao, A., Sairam, S. & Shehata, H. (2004) Obstetric complications of twin pregnancies. Best Pract Res Clin Obstet Gynaecol 18, 557 576.
37. Record, R.G., Mckeown, T. & Edwards, J.H. (1970) An investigation of difference in measured intelligence between twins and single births. Ann Hum Genet 34, 11 20.
38. Reiss, A.L., Abrams, M.T., Singer, H.S., Ross, J.L. & Denckla, M.B. (1996) Brain development, gender and IQ in children. A volumetric imaging study. Brain 119, 1763 1774.
39. Reiss, A.L., Kesler, S.R., Vohr, B., Duncan, C.C., Katz, K.H., Pajot, S., Schneider, K.C., Makuch, R.W. & Ment, L.R. (2004) Sex differences in cerebral columes of 8-year-olds born preterm. J Pediatr 145, 242 249.
40. Sandon, F. (1957) The relative numbers and abilities of some ten-year-old twins. J R Stat Soc Ser B (Methodol) 120, 440 450.
41. Schmitt, J.E., Wallace, G.L., Rosenthal, M.A., Molloy, E.A., Ordaz, S., Lenroot, R., Clasen, L.S., Blumenthal, J.D., Kendler, K.S., Neale, M.C. & Giedd, J.N. (2007) A multivariate analysis of neuroanatomic relationships in a genetically informative pediatric sample. Neuroimage 35, 70 82.
42. Schmitt, J.E., Lenroot, R.K., Wallace, G.L., Ordaz, S., Taylor, K.N., Kabani, N., Greenstein, D., Lerch, J.P., Kendler, K.S., Neale, M.C. & Giedd, J.N. (2008) Identification of genetically mediated cortical networks: a multivariate study of pediatric twins and siblings. Cereb Cortex 18, 1737 1747.
43. Shaw, P., Greenstein, D., Lerch, J., Clasen, L., Lenroot, R., Gogtay, N., Evans, A., Rapoport, J. & Giedd, J. (2006) Intellectual ability and cortical development in children and adolescents. Nature 440, 676 679.
44. Sled, J.G., Zijdenbos, A.P. & Evans, A.C. (1998) A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging 17, 87 97.
45. Tabachnick, B.G. & Fidell, L.S. (2001) Computer-Assisted Research Design and Analysis. Allyn and Bacon
46. Thompson, P.M., Cannon, T.D., Narr, K.L., van Erp, T., Poutanen, V.P., Huttunen, M., Lonnqvist, J., Standertskjold-Nordenstam, C.G., Kaprio, J., Khaledy, M., Dail, R., Zoumalan, C.I. & Toga, A.W. (2001) Genetic influences on brain structure. Nat Neurosci 4, 1253 1258.
47. Wallace, G.L., Schmitt, J.E., Lenroot, R., Viding, E., Ordaz, S., Rosenthal, M.A., Molloy, E.A., Clasen, L.S., Kendler, K.S., Neale, M.C. & Giedd, J.N. (2006) A pediatric twin study of brain morphometry. J Child Psychol Psychiatry 47, 987 993.
48. Wechsler, D. (1999) Wechsler Abbreviated Scale of Intelligence. The Psychological Corporation
49. Wechsler, D. (2002) Wechsler Preschool and Primary Scale of Intelligence, 3rd edn. The Psychological Corporation, Harcourt Brace Jovanovich
50. Wilson, R.S. (1974) Growth standards for twins from birth to four years. Ann Hum Biol 1, 175 188.
51. Wilson, R.S. (1979) Twin growth: initial deficit, recovery, and trends in concordance from birth to nine years. Ann Hum Biol 6, 205 220.
52. Wright, I.C., Sham, P., Murray, R.M., Weinberger, D.R. & Bullmore, E.T. (2002) Genetic contributions to regional variability in human brain structure: methods and preliminary results. Neuroimage 17, 256 271.
53. Zijdenbos, A.P., Forghani, R. & Evans, A.C. (2002) Automatic "pipeline" analysis of 3-D MRI data for clinical trials: application to multiple sclerosis. IEEE Trans Med Imaging 21, 1280 1291.