Mast cell phenotypes and microvessels in non-small cell lung cancer and its prognostic significance

Human Pathology

Volumn 41, Issue 5, 2010, Pages 697-705

  Carlini, María José ^a   Dalurzo, Mercedes Corina Liliana ^b   Lastiri, José María ^b   Smith, David Eduardo ^b   Vasallo, Bartolomé Carlos ^b   Puricelli, Lydia Inés ^a   Lauría de Cidre, Lilia Susana ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b HOSPITAL ITALIANO DE BUENOS AIRES   (Argentina)

Author keywords

Intratumoral; Lung cancer; Mast cell phenotypes; Microvessels; Peritumoral

Indexed keywords

CD34 ANTIGEN; CHYMASE; TRYPTASE;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CELL INFILTRATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG LOBECTOMY; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MAST CELL; MICROVASCULATURE; PHENOTYPE; PROGNOSIS;

AGE FACTORS; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CHI-SQUARE DISTRIBUTION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG; LUNG NEOPLASMS; MALE; MAST CELLS; MICROVESSELS; MIDDLE AGED; NEOPLASM STAGING; NEOVASCULARIZATION, PATHOLOGIC; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC;

EID: 77950692149     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2009.04.029     Document Type: Article

References (33)

1. Matos E.L., Loria D.I., Zengarini N., et al. Atlas of cancer mortality in Argentina 1997-2001 (Spanish) (2003), Fundación Bunge y Born, Buenos Aires (Argentina)
2. Mueller M.M., and Fusening N.E. Friends or foes. Bipolar effects of the tumour stroma in cancer. Nature 4 (2004) 839-849
3. Ribatti D., Ennas M.G., Vacca A., et al. Tumor vascularity and tryptase-positive mast cells correlate with a poor prognosis in melanoma. Eur J Clin Invest 33 (2003) 420-425
4. Mauro L.V., Bellido M., Morandi A., et al. Association between mast cells of different phenotypes and angiogenesis in colorectal cancer. Mol Med Rep 1 (2008) 8
5. Kankkunen J.P., Harvima I.T., and Naukkarinen A. Quantitative analysis of tryptase and chymase containing mast cells in benign and malignant breast lesions. Int J Cancer 72 (1997) 385-388
6. Imada A., Shijubo N., Kojima H., and Abe S. Mast cells correlate with angiogenesis and poor outcome in stage I lung adenocarcinoma. Eur Respir J 15 (2000) 1087-1093
7. Takanami I., Takeuchi K., and Naruke M. Mast cell density is associated with angiogenesis and poor prognosis in pulmonary adenocarcinoma. Cancer 88 (2000) 2686-2692
8. Hallgren J., and Pejler G. Biology of mast cell tryptase. An inflammatory mediator. FEBS J 273 (2006) 1871-1895
9. Blair R.J., Meng H., Marchese M.J., et al. Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor. J Clin Invest 99 (1997) 2691-2700
10. He S., Peng Q., and Walls A.F. Potent induction of a neutrophil and eosinophil-rich infiltrate in vivo by human mast cell tryptase: selective enhancement of eosinophil recruitment by histamine. J Immunol 159 (1997) 6216-6225
11. Kaminska R., Helisalmi P., Harvima R.J., Naukkarinen A., Horsmanheimo M., and Harvima I.T. Focal dermal-epidermal separation and fibronectin cleavage in basement membrane by human mast cell tryptase. J Invest Dermatol 113 (1999) 567-573
12. Yoshii M., Jikuhara A., Mori S., et al. Mast cell tryptase stimulates DLD-1 carcinoma through prostaglandin- and MAP kinase-dependent manners. J Pharmacol Sci 98 (2005) 450-458
13. Muramatsu M., Katada J., Hattori M., Hayashi I., and Majima M. Chymase mediates mast cell-induced angiogenesis in hamster sponge granulomas. Eur J Pharm 402 (2000) 181-191
14. Fang K.C., Raymond W.W., Blount J.L., and Caughey G.H. Dog mast cell alpha-chymase activates progelatinase B by cleaving the Phe88-Gln89 and Phe91-Glu92 bonds of the catalytic domain. J Biol Chem 272 (1997) 25628-25635
15. Theoharides T.C., and Conti P. Mast cells: the Jekyll and Hyde of tumor growth. Trends Immunol 25 (2004) 235-241
16. Norrby K. Mast cells and angiogenesis. APMIS 110 (2002) 355-371
17. Ibaraki T., Muramatsu M., Takai S., et al. The relationship of tryptase- and chymase-positive mast cells to angiogenesis in stage I non-small cell lung cancer. Eur J Cardiothorac Surg 28 (2005) 617-621
18. Tomita M., Matsuzaki Y., and Onitsuka T. Effect of mast cells on tumor angiogenesis in lung cancer. Ann Thorac Surg 69 (2000) 1686-1690
19. Welsh T.J., Green R.H., Richardson D., Waller D.A., O'Byrne K.J., and Bradding P. Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer. J Clin Oncol 23 (2005) 8959-8967
20. Tomita M., Matsuzaki Y., and Onitsuka T. Correlation between mast cells and survival rates in patients with pulmonary adenocarcinoma. Lung Cancer 26 (1999) 103-108
21. Irani A.M., and Schwartz L.B. Mast cell heterogeneity. Clin Exp Allergy 19 (1989) 143-155
22. Cabanillas-Saez A., Schalper J.A., Nicovani S.M., and Rudolph M.I. Characterization of mast cells according to their content of tryptase and chymase in normal and neoplastic human uterine cervix. Int J Gynecol Cancer 12 (2002) 92-98
23. Nagata M., Shijubo N., Walls A.F., Ichimiya S., Abe S., and Sato N. Chymase-positive mast cells in small sized adenocarcinoma of the lung. Virchows Arch 443 (2003) 565-573
24. Rajput A.B., Turbin D.A., Cheang M.C., et al. Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases. Breast Cancer Res Treat 107 (2008) 249-257
25. Nielsen H.J., Hansen U., Christensen I.J., Reimert C.M., Brunner N., and Moesgaard F. Independent prognostic value of eosinophil and mast cell infiltration in colorectal cancer tissue. J Pathol 189 (1999) 487-495
26. Tataroglu C., Kargi A., Ozkal S., Esrefoglu N., and Akkoclu A. Association of macrophages, mast cells and eosinophil leukocytes with angiogenesis and tumor stage in non-small cell lung carcinomas (NSCLC). Lung Cancer 43 (2004) 47-54
27. Dundar E., Oner U., Peker B.C., Metintas M., Isiksoy S., and Ak G. The significance and relationship between mast cells and tumour angiogenesis in non-small cell lung carcinoma. J Int Med Res 36 (2008) 88-95
28. Nienartowicz A., Sobaniec-Lotowska M.E., Jarocka-Cyrta E., and Lemancewicz D. Mast cells in neoangiogenesis. Med Sci Monit 12 (2006) RA53-RA56
29. Folkman J., and Shing Y. Control of angiogenesis by heparin and other sulfated polysaccharides. Adv Exp Med Biol 313 (1992) 355-364
30. Powers C.J., McLeskey S.W., and Wellstein A. Fibroblast growth factors, their receptors and signaling. Endocr Relat Cancer 7 (2000) 165-197
31. Stack M.S., and Johnson D.A. Human mast cell tryptase activates single-chain urinary-type plasminogen activator (pro-urokinase). J Biol Chem 269 (1994) 9416-9419
32. Coussens L.M., Raymond W.W., Bergers G., et al. Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev (1999) 1382-1397
33. de Visser K.E., Eichten A., and Coussens L.M. Paradoxical roles of the immune system during cancer development. Nat Rev Cancer 6 (2006) 24-37