Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin

Arthritis Research and Therapy

Volumn 12, Issue 2, 2010, Pages

  Usui, Chie ^a   Hatta, Kotaro ^a   Doi, Nagafumi ^b   Nakanishi, Atsushi ^a   Nakamura, Hiroyuki ^c   Nishioka, Kusuki ^d   Arai, Heii ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Ibaraki Prefectural Tomobe Hospital   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

^d TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE ETHYL ESTER TC 99M; GABAPENTIN; 4 AMINOBUTYRIC ACID; AMINE; ANALGESIC AGENT; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; CYSTEINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; RADIOPHARMACEUTICAL AGENT; TECHNETIUM COMPLEX; TECHNETIUM TC 99M BICISATE;

ADULT; ARTICLE; BRAIN BLOOD FLOW ABNORMALITY; BRAIN PERFUSION; BRAIN REGION; CEREBROVASCULAR DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROMYALGIA; HUMAN; POSITRON EMISSION TOMOGRAPHY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TREATMENT RESPONSE; VISUAL ANALOG SCALE; AGED; BRAIN; BRAIN CIRCULATION; DRUG EFFECT; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SCINTISCANNING; TREATMENT FAILURE; VASCULARIZATION;

ADULT; AGED; AMINES; ANALGESICS; BRAIN; CEREBROVASCULAR CIRCULATION; CYCLOHEXANECARBOXYLIC ACIDS; CYSTEINE; FEMALE; FIBROMYALGIA; GAMMA-AMINOBUTYRIC ACID; HUMANS; MIDDLE AGED; ORGANOTECHNETIUM COMPOUNDS; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TREATMENT FAILURE; YOUNG ADULT;

EID: 77950685782     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2980     Document Type: Article

References (18)

1. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, Tugwell P, Campbell SM, Abeles M, Clark P, Fam AG, Farber SJ, Fiechtner JJ, Franklin CM, Gatter RA, Hamaty D, Lessard J, Lichtbroun AS, Masi AT, MaCain GA, Reynolds WJ, Romano TJ, Russel IJ, Shoen RP. The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum 1990, 33:160-172. 10.1002/art.1780330203, 2306288.
2. Yunus MB. Central Sensitivity Syndromes 2001, Edinburgh: Churchill Livingstone.
3. Mountz JM, Bradley LA, Alarcon GS. Abnormal functional activity of the central nervous system in fibromyalgia syndrome. Am J Med Sci 1998, 315:385-396. 10.1097/00000441-199806000-00007, 9638895.
4. Kwiatek R, Barnden L, Tedman R, Jarrett R, Chew J, Rowe C, Pile K. Regional cerebral blood flow in fibromyalgia: single-photon-emission computed tomography evidence of reduction in the pontine tegmentum and thalami. Arthritis Rheum 2000, 43:2823-2833. 10.1002/1529-0131(200012)43:12<2823::AID-ANR24>3.0.CO;2-E, 11145042.
5. Guedj E, Taieb D, Cammilleri S, Lussato D, de Laforte C, Niboyet J, Mundler O. 99mTc-ECD brain perfusion SPECT in hyperalgesic fibromyalgia. Eur J Nucl Med Mol Imaging 2007, 34:130-134. 10.1007/s00259-006-0174-7, 16933135.
6. Guedj E, Cammilleri S, Niboyet J, Mundler O. Clinical image: brain perfusion single-photon-emission computed tomography findings in a patient with an asymmetric fibromyalgia syndrome. Arthritis Rheum 2009, 60:298. 10.1002/art.24252, 19116918.
7. Arnold LM, Goldenberg DL, Stanford SB, Lalonde JK, Sandhu HS, Keck PE, Welge JA, Bishop F, Stanford KE, Hess EV, Hudson JI. Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial. Arthritis Rheum 2007, 56:1336-1344. 10.1002/art.22457, 17393438.
8. Lancaster JL, Woldorff MG, Parsons LM, Liotti M, Freitas CS, Rainey L, Kochunov PV, Nickerson D, Mikiten SA, Fox PT. Automated Talairach atlas labels for functional brain mapping. Hum Brain Mapp 2000, 10:120-131. 10.1002/1097-0193(200007)10:3<120::AID-HBM30>3.0.CO;2-8, 10912591.
9. Boly M, Balteau E, Schnakers C, Degueldre C, Moonen G, Luxen A, Phillips C, Peigneux P, Maquet P, Laureys S. Baseline brain activity fluctuations predict somatosensory perception in humans. Proc Natl Acad Sci USA 2007, 104:12187-12192. 10.1073/pnas.0611404104, 1924544, 17616583.
10. Greicius MD, Krasnow B, Reiss AL, Menon V. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci USA 2003, 100:253-258. 10.1073/pnas.0135058100, 140943, 12506194.
11. Shulman GL, Corbetta M, Buckner RL, Raichle ME, Fiez JA, Miezin FM, Petersen SE. Top-down modulation of early sensory cortex. Cereb Cortex 1997, 7:193-206. 10.1093/cercor/7.3.193, 9143441.
12. Raichle ME. Neuroscience. The brain's dark energy. Science 2006, 314:1249-1250. 10.1126/science. 1134405, 17124311.
13. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van Essen DC, Raichle ME. The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci USA 2005, 102:9673-9678. 10.1073/pnas.0504136102, 1157105, 15976020.
14. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL. A default mode of brain function. Proc Natl Acad Sci USA 2001, 98:676-682. 10.1073/pnas.98.2.676, 14647, 11209064.
15. Seminowicz DA, Davis KD. Pain enhances functional connectivity of a brain network evoked by performance of a cognitive task. J Neurophysiol 2007, 97:3651-3659. 10.1152/jn.01210.2006, 17314240.
16. Baliki MN, Geha PY, Apkarian AV, Chialvo DR. Beyond feeling: chronic pain hurts the brain, disrupting the default-mode network dynamics. J Neurosci 2008, 28:1398-1403. 10.1523/JNEUROSCI.4123-07.2008, 18256259.
17. Crofford LJ, Rowbotham MC, Mease PJ, Russell IJ, Dworkin RH, Corbin AE, Young JP, LaMoreaux LK, Martin SA, Sharma U. Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2005, 52:1264-1273. 10.1002/art.20983, 15818684.
18. Guedj E, Cammilleri S, Colavolpe C, Taieb D, de Laforte C, Niboyet J, Mundler O. Predictive value of brain perfusion SPECT for ketamine response in hyperalgesic fibromyalgia. Eur J Nucl Med Mol Imaging 2007, 34:1274-1279. 10.1007/s00259-007-0392-7, 17431615.