Gs signaling in osteoblasts and hematopoietic stem cells

Annals of the New York Academy of Sciences

Volumn 1192, Issue , 2010, Pages 327-329

  Kronenberg, Henry M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Bone; Gs; Hematopoietic stem cell; Osteoblast

Indexed keywords

CRE RECOMBINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR;

ALPHA CHAIN; ANIMAL CELL; B LYMPHOCYTE; BONE MARROW; CELL DIFFERENTIATION; CELL MATURATION; CONFERENCE PAPER; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE DELETION; HEMATOPOIETIC STEM CELL; HOST CELL; LIVER; MOUSE; NONHUMAN; OSTEOBLAST; SIGNAL TRANSDUCTION;

MUS;

EID: 77950685384     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.05251.x     Document Type: Conference Paper

References (4)

1. Yu, S.,D.Yu, E. Lee, et al. 1998.Variable and tissue-specific hormone resistance in heterotrimeric Gs protein alphasubunit (Gsalpha) knockout mice is due to tissue-specific imprinting of the gsalpha gene. Proc. Natl. Acad. Sci. USA 95: 8715-8720.
2. Wu, J., C. Maes, M. Chen, et al. 2008. Deletion of the G protein subunit Gs alpha in early osteoblasts leads to accelerated osteoblast maturation and formation of woven bone with abnormal osteocytes. J. Bone Min. Res. 23(Suppl. 1): Abst 1254.
3. Wu, J.Y., L.E. Purton, S.J. Rodda, et al. 2008. Osteoblastic regulation of B lymphopoiesis is mediated by Gs[alpha]- dependent signaling pathways. Proc. Natl. Acad. Sci. USA 105: 16976-16981.
4. Adams, G.B., I.R. Alley, U.I. Chung, et al. 2009. Haematopoietic stem cells depend on Galpha(s)- mediated signalling to engraft bone marrow. Nature 459: 103-107.