Modulation of the activity of cytosolic phospholipase A2α (cPLA2α) by cellular sphingolipids and inhibition of cPLA2α by sphingomyelin

Journal of Lipid Research

Volumn 51, Issue 4, 2010, Pages 720-728

  Nakamura, Hiroyuki ^a   Wakita, Shigeo ^a   Suganami, Akiko ^b   Tamura, Yutaka ^b   Hanada, Kentaro ^c,d   Murayama, Toshihiko ^a  

^a Graduate School of Pharmaceutical Sciences   (United States)

^b CHIBA UNIVERSITY   (Japan)

^c Department of Biochemistry and Cell Biology ^*  (United States)

^d NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Arachidonic acid; Chinese hamster ovary cells; Glycerophospholipids

Indexed keywords

ARACHIDONIC ACID; CALCIMYCIN; CARRIER PROTEIN; CERAMIDE; CYTOSOLIC PHOSPHOLIPASE A2; GLYCEROPHOSPHOLIPID; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A2 INHIBITOR; SERINE PALMITOYLTRANSFERASE; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE INHIBITOR; SPHINGOSINE; ENZYME INHIBITOR; ERYTHRO-(2R,3S)-SPHINGOSINE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; LIPOSOME; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE A2 GROUP IV; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL VACUOLE; CHO CELL; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SUBUNIT; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; LIPOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; CHO CELL LINE; CRICETULUS; DRUG EFFECTS; GENETICS; HAMSTER; METABOLISM; MUTATION; PHOSPHORYLATION; PROTEIN TRANSPORT;

ANIMALS; ARACHIDONIC ACID; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLYCEROPHOSPHOLIPIDS; GREEN FLUORESCENT PROTEINS; GROUP IV PHOSPHOLIPASES A2; HUMANS; LIPOSOMES; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; SPHINGOLIPIDS; SPHINGOMYELINS; SPHINGOSINE;

EID: 77950625075     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M002428     Document Type: Article

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