-
1
-
-
0014732778
-
Preliminary model for methotrexate pharmacokinetics
-
Bischoff, K. B., Dedrick, R. L., and Zaharko, D. S. (1970). Preliminary model for methotrexate pharmacokinetics. J. Pharm. Sci. 59, 149-154.
-
(1970)
J. Pharm. Sci.
, vol.59
, pp. 149-154
-
-
Bischoff, K.B.1
Dedrick, R.L.2
Zaharko, D.S.3
-
2
-
-
0015103210
-
Methotrexate pharmacokinetics
-
Bischoff, K. B., Dedrick, R. L., Zaharko, D. S., and Longstreth, J. A. (1971). Methotrexate pharmacokinetics. J. Pharm. Sci. 60, 1128-1133.
-
(1971)
J. Pharm. Sci.
, vol.60
, pp. 1128-1133
-
-
Bischoff, K.B.1
Dedrick, R.L.2
Zaharko, D.S.3
Longstreth, J.A.4
-
3
-
-
0037812407
-
Clinical pharmacokinetic/pharmacodynamic and physiologically based pharmacokinetic modeling in new drug development: The capecitabine experience
-
Blesch, K. S., Gieschke, R., Tsukamoto, Y., Reigner, B. G., Burger, H. U., and Steimer, J. L. (2003). Clinical pharmacokinetic/pharmacodynamic and physiologically based pharmacokinetic modeling in new drug development: The capecitabine experience. Invest. New Drugs 21, 195-223.
-
(2003)
Invest. New Drugs
, vol.21
, pp. 195-223
-
-
Blesch, K.S.1
Gieschke, R.2
Tsukamoto, Y.3
Reigner, B.G.4
Burger, H.U.5
Steimer, J.L.6
-
4
-
-
0018121445
-
Prediction of adrimycin disposition in cancer patients using a physiologic, pharmacokinetic model
-
Chan, K. K., Cohen, J. L., Gross, J. F., Himmelstein, K. J., Bateman, J. R., Tsu-Lee, Y., and Marlis, A. S. (1978). Prediction of adrimycin disposition in cancer patients using a physiologic, pharmacokinetic model. Cancer Treat. Rep. 62, 1161-1171.
-
(1978)
Cancer Treat. Rep.
, vol.62
, pp. 1161-1171
-
-
Chan, K.K.1
Cohen, J.L.2
Gross, J.F.3
Himmelstein, K.J.4
Bateman, J.R.5
Tsu-Lee, Y.6
Marlis, A.S.7
-
5
-
-
0018936361
-
Non-linear pharmacokinetic models for 5-fluorouracil in man: Intravenous and intraperitoneal routes
-
Collins, J. M., Dedrick, R. L., King, F. G., Speyer, J. L., and Myers, C. E. (1980). Non-linear pharmacokinetic models for 5-fluorouracil in man: Intravenous and intraperitoneal routes. Clin. Pharmacol. Ther. 28, 235-246.
-
(1980)
Clin. Pharmacol. Ther.
, vol.28
, pp. 235-246
-
-
Collins, J.M.1
Dedrick, R.L.2
King, F.G.3
Speyer, J.L.4
Myers, C.E.5
-
6
-
-
0015259181
-
In vitro-in vivo correlation of drug metabolism- Deamination of 1-b-d-arabinofuranosylcytosine
-
Dedrick, R. L., Forrester, D. D., and Ho, D. H. W. (1972). In vitro-in vivo correlation of drug metabolism- Deamination of 1-b-d-arabinofuranosylcytosine. Biochem. Pharmacol. 21, 1-16.
-
(1972)
Biochem. Pharmacol.
, vol.21
, pp. 1-16
-
-
Dedrick, R.L.1
Forrester, D.D.2
Ho, D.H.W.3
-
7
-
-
0015896830
-
Pharmacokinentics of 1-b-d-arabinofuranosylcytosine (Ara-C) deamination in several species
-
Dedrick, R. L., Forrester, D. D., Cannon, J. N., El Dareer, S. M., and Mellett, L. B. (1973a). Pharmacokinentics of 1-b-d-arabinofuranosylcytosine (Ara-C) deamination in several species. Biochem. Pharmacol. 22, 2405-2417.
-
(1973)
Biochem. Pharmacol.
, vol.22
, pp. 2405-2417
-
-
Dedrick, R.L.1
Forrester, D.D.2
Cannon, J.N.3
El Dareer, S.M.4
Mellett, L.B.5
-
8
-
-
0015635144
-
Transport and binding of methotrexate in vivo
-
Dedrick, R. L., Zaharko, D. S., and Lutz, R. J. (1973b). Transport and binding of methotrexate in vivo. J. Pharm. Sci. 62, 882-890.
-
(1973)
J. Pharm. Sci.
, vol.62
, pp. 882-890
-
-
Dedrick, R.L.1
Zaharko, D.S.2
Lutz, R.J.3
-
9
-
-
0016205279
-
Device for controlled drug release- Application to methotrexate infusion in mice
-
Dedrick, R. L., Zaharko, D. S., Lutz, R. J., and Drake, J. C. (1974). Device for controlled drug release- Application to methotrexate infusion in mice. Biochem. Pharmacol. 23, 2457-2461.
-
(1974)
Biochem. Pharmacol.
, vol.23
, pp. 2457-2461
-
-
Dedrick, R.L.1
Zaharko, D.S.2
Lutz, R.J.3
Drake, J.C.4
-
10
-
-
0017853566
-
Pharmacokinetic rationale for peritoneal drug administration in the treatment of ovarian cancer
-
Dedrick, R. L., Myers, C. E., Bungay, P. M., and DeVita, V. T. (1978). Pharmacokinetic rationale for peritoneal drug administration in the treatment of ovarian cancer. Cancer Treat. Rep. 62, 1-11.
-
(1978)
Cancer Treat. Rep.
, vol.62
, pp. 1-11
-
-
Dedrick, R.L.1
Myers, C.E.2
Bungay, P.M.3
DeVita, V.T.4
-
11
-
-
0020353524
-
Pharmacokinetic modeling of cisplatin disposition in children and adolescents with cancer
-
Evans, W. E., Crom, W. R., Tsiatis, A., Green, A. A., Hayes, F. A., and Pratt, C. B. (1982). Pharmacokinetic modeling of cisplatin disposition in children and adolescents with cancer. Cancer Chemother. Pharmacol. 10, 22-26.
-
(1982)
Cancer Chemother. Pharmacol.
, vol.10
, pp. 22-26
-
-
Evans, W.E.1
Crom, W.R.2
Tsiatis, A.3
Green, A.A.4
Hayes, F.A.5
Pratt, C.B.6
-
12
-
-
0021857519
-
Physiological model for the pharmacokinetics of cis-dichlorodiammineplatinum (II) (DDP) in the tumored rat
-
Farris, F. F., King, F. G., Dedrick, R. L., and Litterst, C. L. (1985). Physiological model for the pharmacokinetics of cis-dichlorodiammineplatinum (II) (DDP) in the tumored rat. J. Pharmacokinet. Biopharm. 13, 13-39.
-
(1985)
J. Pharmacokinet. Biopharm.
, vol.13
, pp. 13-39
-
-
Farris, F.F.1
King, F.G.2
Dedrick, R.L.3
Litterst, C.L.4
-
13
-
-
0036282896
-
Doxorubicin pharmacokinetics: Macromolecule binding, metabolism, and excretion in the context of a physiologic model
-
Gustafson, D. L., Rastatter, J. C., Colombo, T., and Long, M. E. (2002). Doxorubicin pharmacokinetics: Macromolecule binding, metabolism, and excretion in the context of a physiologic model. J. Pharm. Sci. 91, 1488-1501.
-
(2002)
J. Pharm. Sci.
, vol.91
, pp. 1488-1501
-
-
Gustafson, D.L.1
Rastatter, J.C.2
Colombo, T.3
Long, M.E.4
-
14
-
-
0016800963
-
Preliminary pharmacokinetic model for adriamycin (NSC-123-127)
-
Harris, P. A., and Gross, J. F. (1975). Preliminary pharmacokinetic model for adriamycin (NSC-123-127). Cancer Chemother. Rep. 59, 819-825.
-
(1975)
Cancer Chemother. Rep.
, vol.59
, pp. 819-825
-
-
Harris, P.A.1
Gross, J.F.2
-
15
-
-
0018567602
-
Pharmacokinetic model for 2-amino-1,3,4-thiadiazole in mouse, dog, and monkey
-
King, F. G., and Dedrick, R. L. (1979). Pharmacokinetic model for 2-amino-1,3,4-thiadiazole in mouse, dog, and monkey. Cancer Treat. Rep. 63, 1939-1947.
-
(1979)
Cancer Treat. Rep.
, vol.63
, pp. 1939-1947
-
-
King, F.G.1
Dedrick, R.L.2
-
16
-
-
0019868427
-
Physiologic model for the pharmacokinetics of 2' deoxycoformycin in normal and leukemic mice
-
King, F. G., and Dedrick, R. L. (1981). Physiologic model for the pharmacokinetics of 2' deoxycoformycin in normal and leukemic mice. J. Pharmacokinet. Biopharm. 9, 519-534.
-
(1981)
J. Pharmacokinet. Biopharm.
, vol.9
, pp. 519-534
-
-
King, F.G.1
Dedrick, R.L.2
-
17
-
-
0026665647
-
Physiological pharmacokinetic parameters for cisdichlorodiammineplatinum( II) (DDP) in the mouse
-
King, F. G., and Dedrick, R. L. (1992). Physiological pharmacokinetic parameters for cisdichlorodiammineplatinum( II) (DDP) in the mouse. J. Pharmacokinet. Biopharm. 20, 95-99.
-
(1992)
J. Pharmacokinet. Biopharm.
, vol.20
, pp. 95-99
-
-
King, F.G.1
Dedrick, R.L.2
-
18
-
-
0022447460
-
Physiological pharmacokinetic modeling of cisdichlorodiammineplatinum( II) (DDP) in several species
-
King, F. G., Dedrick, R. L., and Farris, F. F. (1986). Physiological pharmacokinetic modeling of cisdichlorodiammineplatinum( II) (DDP) in several species. J. Pharmacokinet. Biopharm. 14, 131-154.
-
(1986)
J. Pharmacokinet. Biopharm.
, vol.14
, pp. 131-154
-
-
King, F.G.1
Dedrick, R.L.2
Farris, F.F.3
-
19
-
-
0018741447
-
Pharmacokinetic study of cis-dichlorodiammineplatinum(II) (DDP) in the beagle dog: Thermodynamic and kinetic behavior of DDP in a biologic milieu
-
LeRoy, A. F., Lutz, R. J., Dedrick, R. L., Litterst, C. L., and Guarino, A. M. (1979). Pharmacokinetic study of cis-dichlorodiammineplatinum(II) (DDP) in the beagle dog: Thermodynamic and kinetic behavior of DDP in a biologic milieu. Cancer Treat. Rep. 63, 59-71.
-
(1979)
Cancer Treat. Rep.
, vol.63
, pp. 59-71
-
-
LeRoy, A.F.1
Lutz, R.J.2
Dedrick, R.L.3
Litterst, C.L.4
Guarino, A.M.5
-
20
-
-
0036448111
-
The effect of malignant effusions on methotrexate disposition
-
Li, J., and Gwilt, P. (2002). The effect of malignant effusions on methotrexate disposition. Cancer Chemother. Pharmacol. 50, 373-382.
-
(2002)
Cancer Chemother. Pharmacol.
, vol.50
, pp. 373-382
-
-
Li, J.1
Gwilt, P.2
-
21
-
-
0016684524
-
The kinetics of methotrexate distribution in spontaneous canine lymphosarcoma
-
Lutz, R. J., Dedrick, R. L., Straw, J. A., Hart, M. M., Klubes, P., and Zaharko, D. S. (1975). The kinetics of methotrexate distribution in spontaneous canine lymphosarcoma. J. Pharmacokinet. Biopharm. 3, 77-97.
-
(1975)
J. Pharmacokinet. Biopharm.
, vol.3
, pp. 77-97
-
-
Lutz, R.J.1
Dedrick, R.L.2
Straw, J.A.3
Hart, M.M.4
Klubes, P.5
Zaharko, D.S.6
-
22
-
-
0017364792
-
A model for the kinetics of distribution of actinomycin-D in the beagle dog
-
Lutz, R. J., Galbraith, W. M., Dedrick, R. L., Shrage, R., and Mellett, L. B. (1977). A model for the kinetics of distribution of actinomycin-D in the beagle dog. J. Pharmacol. Exp. Ther. 200, 469-478.
-
(1977)
J. Pharmacol. Exp. Ther.
, vol.200
, pp. 469-478
-
-
Lutz, R.J.1
Galbraith, W.M.2
Dedrick, R.L.3
Shrage, R.4
Mellett, L.B.5
-
23
-
-
0019784273
-
Development and identification of a multicompartment model for the distribution of adriamycin in the rat
-
Sonneveld, P., and Mulder, J. A. (1981). Development and identification of a multicompartment model for the distribution of adriamycin in the rat. J. Pharmacokinet. Biopharm. 9, 577-601.
-
(1981)
J. Pharmacokinet. Biopharm.
, vol.9
, pp. 577-601
-
-
Sonneveld, P.1
Mulder, J.A.2
-
24
-
-
0027940704
-
A pharmacokinetic model of topotecan clearance from plasma and cerebrospinal fluid
-
Sung, C., Blaney, S. M., Cole, D. E., Balis, F. M., and Dedrick, R. L. (1994). A pharmacokinetic model of topotecan clearance from plasma and cerebrospinal fluid. Cancer Res. 54, 5118-5122.
-
(1994)
Cancer Res.
, vol.54
, pp. 5118-5122
-
-
Sung, C.1
Blaney, S.M.2
Cole, D.E.3
Balis, F.M.4
Dedrick, R.L.5
-
25
-
-
0034807893
-
A physiologically based pharmacokinetic analysis of capecitabine, a triple prodrug of 5-FU, in humans: The mechanism for tumor-selective accumulation of 5-FU
-
Tsukamoto, Y., Kato, Y., Ura, M., Horii, I., Ishitsuka, H., Kusuhara, H., and Sugiyama, Y. (2001a). A physiologically based pharmacokinetic analysis of capecitabine, a triple prodrug of 5-FU, in humans: The mechanism for tumor-selective accumulation of 5-FU. Pharmacol. Res. 18, 1190-1202.
-
(2001)
Pharmacol. Res.
, vol.18
, pp. 1190-1202
-
-
Tsukamoto, Y.1
Kato, Y.2
Ura, M.3
Horii, I.4
Ishitsuka, H.5
Kusuhara, H.6
Sugiyama, Y.7
-
26
-
-
0035188291
-
Investigation of 5-FU disposition after oral administration of capecitabine, a triple prodrug of 5-FU, using a physiologically based pharmacokinetic model in a human cancer xenograft model: Comparison of the simulated 5-FU exposures in the tumor tissue between human and xenograft model
-
Tsukamoto, Y., Kato, Y., Ura, M., Horii, I., Ishikawa, T., Ishitsuka, H., and Sugiyama, Y. (2001b). Investigation of 5-FU disposition after oral administration of capecitabine, a triple prodrug of 5-FU, using a physiologically based pharmacokinetic model in a human cancer xenograft model: Comparison of the simulated 5-FU exposures in the tumor tissue between human and xenograft model. Biopharm. Drug Dispos. 22, 1-14.
-
(2001)
Biopharm. Drug Dispos.
, vol.22
, pp. 1-14
-
-
Tsukamoto, Y.1
Kato, Y.2
Ura, M.3
Horii, I.4
Ishikawa, T.5
Ishitsuka, H.6
Sugiyama, Y.7
-
27
-
-
0030885657
-
Tissue and perfusate pharmacokinetics of melphalan in isolated perfused rat hindlimb
-
Wu, Z.-Y., Smithers, B. M., and Roberts, M. S. (1997). Tissue and perfusate pharmacokinetics of melphalan in isolated perfused rat hindlimb. J. Pharmacol. Exp. Ther. 282, 1131-1138.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.282
, pp. 1131-1138
-
-
Wu, Z.-Y.1
Smithers, B.M.2
Roberts, M.S.3
-
28
-
-
0141729370
-
Physiologically-based pharmacokinetics and molecular pharmacodynamics of 17-(allylamino)-17-demethoxygeldanamycin and its active metabolite in tumor-bearing mice
-
Xu, L., Eiseman, J. L., Egorin, M. J., and D'Argenio, D. Z. (2003). Physiologically-based pharmacokinetics and molecular pharmacodynamics of 17-(allylamino)-17-demethoxygeldanamycin and its active metabolite in tumor-bearing mice. J. Pharmacokinetic. Biopharm. 30, 185-218.
-
(2003)
J. Pharmacokinetic. Biopharm.
, vol.30
, pp. 185-218
-
-
Xu, L.1
Eiseman, J.L.2
Egorin, M.J.3
D'Argenio, D.Z.4
-
29
-
-
0015344370
-
Prediction of the distribution of methotrexate in the sting rays Dasyatidae sabina and sayi by use of a model developed in mice
-
Zaharko, D. S., Dedrick, R. L., and Oliverio, V. T. (1972). Prediction of the distribution of methotrexate in the sting rays Dasyatidae sabina and sayi by use of a model developed in mice. Comp. Biochem. Physiol. A 42, 183-194.
-
(1972)
Comp. Biochem. Physiol. A
, vol.42
, pp. 183-194
-
-
Zaharko, D.S.1
Dedrick, R.L.2
Oliverio, V.T.3
-
30
-
-
0016074441
-
Relative toxicity of methotrexate in several tissues of mice bearing Lewis lung carcinoma
-
Zaharko, D. S., Dedrick, R. L., Peale, A. L., Drake, J. C., and Lutz, R. J. (1974). Relative toxicity of methotrexate in several tissues of mice bearing Lewis lung carcinoma. J. Pharmacol. Exp. Ther. 189, 585-592.
-
(1974)
J. Pharmacol. Exp. Ther.
, vol.189
, pp. 585-592
-
-
Zaharko, D.S.1
Dedrick, R.L.2
Peale, A.L.3
Drake, J.C.4
Lutz, R.J.5
|