Core and suggestive symptoms of dementia with lewy bodies cluster in persons with mild dementia

Dementia and Geriatric Cognitive Disorders

Volumn 29, Issue 4, 2010, Pages 317-324

  Rongve, Arvid ^a   Brønnick, Kolbjørn ^b   Ballard, Clive ^c   Aarsland, Dag ^b  

^a HAUGESUND HOSPITAL   (Norway)

^b STAVANGER UNIVERSITY HOSPITAL   (Norway)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Cluster analysis; Dementia; Lewy bodies

Indexed keywords

AGED; ARTICLE; CLUSTER ANALYSIS; COGNITIVE DEFECT; CONTROLLED STUDY; DEMENTIA; DIFFUSE LEWY BODY DISEASE; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HALLUCINATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MILD COGNITIVE IMPAIRMENT; NORWAY; PARASOMNIA; PARKINSONISM; PRIORITY JOURNAL; RATING SCALE; SCORING SYSTEM; SYMPTOM;

AGED; AGED, 80 AND OVER; CLUSTER ANALYSIS; COGNITION; FEMALE; HALLUCINATIONS; HUMANS; LEWY BODY DISEASE; MALE; MOTOR ACTIVITY; PARKINSONIAN DISORDERS; SEVERITY OF ILLNESS INDEX; SLEEP, REM; SPACE PERCEPTION; VISUAL PERCEPTION;

EID: 77950615418     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000295111     Document Type: Article

References (36)

1. McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, Feldman H, Cummings J, Duda JE, Lippa C, Perry EK, Aarsland D, Arai H, Ballard CG, Boeve B, Burn DJ, Costa D, Del Ser T, Dubois B, Galasko D, Gauthier S, Goetz CG, Gomez-Tortosa E, Halliday G, Hansen LA, Hardy J, Iwatsubo T, Kalaria RN, Kaufer D, Kenny RA, Korczyn A, Kosaka K, Lee VM, Lees A, Litvan I, Londos E, Lopez OL, Minoshima S, Mizuno Y, Molina JA, Mukaetova-Ladinska EB, Pasquier F, Perry RH, Schulz JB, Trojanowski JQ, Yamada M: Diagnosis and management of dementia with Lewy bodies: third report of the DLB consortium. Neurology 2005; 65: 1863-1872.
2. Perry R, McKeith I, Perry E: Dementia with Lewy Bodies: Clinical, Pathological, and Treatment Issues. Cambridge, Cambridge University Press, 1996.
3. Okazaki H, Lipkin LE, Aronson SM: Diffuse intracytoplasmic ganglionic inclusions (Lewy type) associated with progressive dementia and quadriparesis in flexion. J Neuropathol Exp Neurol 1961; 20: 237-244.
4. Hohl U, Tiraboschi P, Hansen LA, Thal LJ, Corey-Bloom J: Diagnostic accuracy of dementia with Lewy bodies. Arch Neurol 2000; 57: 347-351.
5. Jellinger KA, Attems J: Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease. Acta Neuropathol 2008; 115: 427-436.
6. Kosaka K: Dementia with Lewy bodies - from its finding to the present, including the CDLB guideline-revised (in Japanese). Rinsho Shinkeigaku 2007; 47: 703-707.
7. Hansen L, Salmon D, Galasko D, Masliah E, Katzman R, DeTeresa R, Thal L, Pay MM, Hofstetter R, Klauber M, et al: The Lewy body variant of Alzheimer's disease: a clinical and pathologic entity. Neurology 1990; 40: 1-8.
8. Lippa CF, Emre M: Characterizing clinical phenotypes: the Lewys in their life or the life of their Lewys? Neurology 2006; 67: 1910-1911.
9. Lippa CF, Duda JE, Grossman M, Hurtig HI, Aarsland D, Boeve BF, Brooks DJ, Dickson DW, Dubois B, Emre M, Fahn S, Farmer JM, Galasko D, Galvin JE, Goetz CG, Growdon JH, Gwinn-Hardy KA, Hardy J, Heutink P, Iwatsubo T, Kosaka K, Lee VM, Leverenz JB, Masliah E, McKeith IG, Nussbaum RL, Olanow CW, Ravina BM, Singleton AB, Tanner CM, Trojanowski JQ, Wszolek ZK: DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers. Neurology 2007; 68: 812-819.
10. McKeith IG, Perry EK, Perry RH: Report of the Second Dementia with Lewy Body International Workshop: diagnosis and treatment. Consortium on Dementia with Lewy Bodies. Neurology 1999; 53: 902-905.
11. Tiraboschi P, Salmon DP, Hansen LA, Hofstetter RC, Thal LJ, Corey-Bloom J: What best differentiates Lewy body from Alzheimer's disease in early-stage dementia? Brain 2006; 129: 729-735.
12. Ballard C, Ziabreva I, Perry R, Larsen JP, O'Brien J, McKeith I, Perry E, Aarsland D: Differences in neuropathologic characteristics across the Lewy body dementia spectrum. Neurology 2006; 67: 1931-1934.
13. Merdes AR, Hansen LA, Jeste DV, Galasko D, Hofstetter CR, Ho GJ, Thal LJ, Corey- Bloom J: Influence of Alzheimer pathology on clinical diagnostic accuracy in dementia with Lewy bodies. Neurology 2003; 60: 1586-1590.
14. Ferman TJ, Smith GE, Boeve BF, Ivnik RJ, Petersen RC, Knopman D, Graff-Radford N, Parisi J, Dickson DW: DLB fluctuations: specific features that reliably differentiate DLB from AD and normal aging. Neurology 2004; 62: 181-187.
15. Aarsland D, Rongve A, Nore SP, Skogseth R, Skulstad S, Ehrt U, Hoprekstad D, Ballard C: Frequency and case identification of dementia with Lewy bodies using the revised consensus criteria. Dement Geriatr Cogn Disord 2008; 26: 445-452.
16. Cummings JL, Mega M, Gray K, Rosenberg- Thompson S, Carusi DA, Gornbein J: The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 1994; 44: 2308-2314.
17. Fahn S, Elton R, Members of the UPDRS Development Committee: Unified Parkinson's Disease Rating Scale; in Fahn S, Marsden CD, Calne DB, Goldstein M (eds): Recent Developments in Parkinson's Disease. Florham Park, MacMillan Health Care Information, 1987, pp 153-163.
18. Walker MP, Ayre GA, Cummings JL, Wesnes K, McKeith IG, O'Brien JT, Ballard CG: The clinician assessment of fluctuation and the one day fluctuation assessment scale: two methods to assess fluctuating confusion in dementia. Br J Psychiatry 2000; 177: 252-256.
19. Boeve BF, Ferman TJ, Silber MH, Smith GE: Validation of a questionnaire of REM sleep behavior disorder. Neurology 2002; 58(suppl 3):A509.
20. Delis D, Kramer JH, Kaplan E, Ober B: California Verbal Learning Test: Adult Version Manual. San Antonio, Psychological Corporation, 1987.
21. Warrington E, James M: The Visual Object and Space Perception Battery. San Antonio, Psychological Corporation, 1991.
22. Steinberg BA, Bieliauskas LA, Smith GE, Ivnik RJ: Mayo's older Americans normative studies: age- and IQ-adjusted norms for the trail-making test, the Stroop test, and MAE controlled oral word association test. Clin Neuropsychol 2005; 19: 329-377.
23. Golden CJ: Stroop color and word test. Chicago, Stoelting, 1978.
24. Chiu T, Fang D, Chen J, Wang Y, Jeris C: A robust and scalable clustering algorithm for mixed type attributes in large database environment. 7th SIGKDD Int Conf Knowledge Discovery Data Mining, San Francesco, 2001.
25. Zhang T, Ramakrishnon R, Livny M: An efficient data clustering method for very large databases. ACM SIGMOD Conf Manage Data, Montreal, 1996.
26. Nervi A, Reitz C, Tang MX, Santana V, Piriz A, Reyes-Dumeyer D, Lantigua R, Medrano M, Jimenez-Velazquez IZ, Lee JH, Mayeux R: Comparison of clinical manifestations in Alzheimer disease and dementia with Lewy bodies. Arch Neurol 2008; 65: 1634-1639.
27. Hamilton JM, Salmon DP, Galasko D, Raman R, Emond J, Hansen LA, Masliah E, Thal LJ: Visuospatial deficits predict rate of cognitive decline in autopsy-verified dementia with Lewy bodies. Neuropsychology 2008; 22: 729-737.
28. Boeve BF, Silber MH, Parisi JE, Dickson DW, Ferman TJ, Benarroch EE, Schmeichel AM, Smith GE, Petersen RC, Ahlskog JE, Matsumoto JY, Knopman DS, Schenck CH, Mahowald MW: Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism. Neurology 2003; 61: 40-45.
29. Boeve BF, Silber MH, Saper CB, Ferman TJ, Dickson DW, Parisi JE, Benarroch EE, Ahlskog JE, Smith GE, Caselli RC, Tippman- Peikert M, Olson EJ, Lin SC, Young T, Wszolek Z, Schenck CH, Mahowald MW, Castillo PR, Del Tredici K, Braak H: Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain 2007; 130: 2770-2788.
30. Fronczek R, Overeem S, Lee SY, Hegeman IM, van Pelt J, van Duinen SG, Lammers GJ, Swaab DF: Hypocretin (orexin) loss in Parkinson's disease. Brain 2007; 130: 1577-1585.
31. Boeve BF, Silber MH, Ferman TJ: REM sleep behavior disorder in Parkinson's disease and dementia with Lewy bodies. J Geriatr Psychiatry Neurol 2004; 17: 146-157.
32. Schmeichel AM, Buchhalter LC, Low PA, Parisi JE, Boeve BW, Sandroni P, Benarroch EE: Mesopontine cholinergic neuron involvement in Lewy body dementia and multiple system atrophy. Neurology 2008; 70: 368-373.
33. Ballard CG, Jacoby R, Del Ser T, Khan MN, Munoz DG, Holmes C, Nagy Z, Perry EK, Joachim C, Jaros E, O'Brien JT, Perry RH, McKeith IG: Neuropathological substrates of psychiatric symptoms in prospectively studied patients with autopsy-confirmed dementia with Lewy bodies. Am J Psychiatry 2004; 161: 843-849.
34. O'Brien JT, McKeith IG, Walker Z, Tatsch K, Booij J, Darcourt J, Marquardt M, Reininger C: Diagnostic accuracy of 123 I-FP-CIT SPECT in possible dementia with Lewy bodies. Br J Psychiatry 2009; 194: 34-39.
35. Suzuki M, Kurita A, Hashimoto M, Fukumitsu N, Abo M, Ito Y, Urashima M, Inoue K: Impaired myocardial (123)I-metaiodobenzylguanidine uptake in Lewy body disease: comparison between dementia with Lewy bodies and Parkinson's disease. J Neurol Sci 2006; 240: 15-19.
36. Molloy S, McKeith IG, O'Brien JT, Burn DJ: The role of levodopa in the management of dementia with Lewy bodies. J Neurol Neurosurg Psychiatry 2005; 76: 1200-1203.