메뉴 건너뛰기




Volumn 8, Issue 3, 2010, Pages 194-198

Utility of DNA methylation markers for diagnosing cancer

Author keywords

Biomarker; Cancer; DNA methylation

Indexed keywords

DNA METHYLTRANSFERASE; GENOMIC DNA;

EID: 77950595010     PISSN: 17439191     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijsu.2010.02.001     Document Type: Review
Times cited : (65)

References (74)
  • 1
    • 0038576158 scopus 로고    scopus 로고
    • The power and the promise of DNA methylation markers
    • Laird P.W. The power and the promise of DNA methylation markers. Nat Rev Cancer 3 (2003) 253-266
    • (2003) Nat Rev Cancer , vol.3 , pp. 253-266
    • Laird, P.W.1
  • 2
    • 60249094056 scopus 로고    scopus 로고
    • Silencing of MBD1 and MeCP2 in prostate-cancer-derived PC3 cells produces differential gene expression profiles and cellular phenotypes
    • Yaqinuddin A., Abbas F., Naqvi S.Z., Bashir M.U., Qazi R., and Qureshi S.A. Silencing of MBD1 and MeCP2 in prostate-cancer-derived PC3 cells produces differential gene expression profiles and cellular phenotypes. Biosci Rep 28 (2008) 319-326
    • (2008) Biosci Rep , vol.28 , pp. 319-326
    • Yaqinuddin, A.1    Abbas, F.2    Naqvi, S.Z.3    Bashir, M.U.4    Qazi, R.5    Qureshi, S.A.6
  • 3
    • 53949094967 scopus 로고    scopus 로고
    • Down-regulation of DNMT3b in PC3 cells effects locus-specific DNA methylation, and represses cellular growth and migration
    • Yaqinuddin A., Qureshi S.A., Qazi R., and Abbas F. Down-regulation of DNMT3b in PC3 cells effects locus-specific DNA methylation, and represses cellular growth and migration. Cancer Cell Int 8 (2008) 13
    • (2008) Cancer Cell Int , vol.8 , pp. 13
    • Yaqinuddin, A.1    Qureshi, S.A.2    Qazi, R.3    Abbas, F.4
  • 4
    • 67649794774 scopus 로고    scopus 로고
    • DNMT1 silencing affects locus specific DNA methylation and increases prostate cancer derived PC3 cell invasiveness
    • Yaqinuddin A., Qureshi S.A., Qazi R., Farooq S., and Abbas F. DNMT1 silencing affects locus specific DNA methylation and increases prostate cancer derived PC3 cell invasiveness. J Urol 182 (2009) 756-761
    • (2009) J Urol , vol.182 , pp. 756-761
    • Yaqinuddin, A.1    Qureshi, S.A.2    Qazi, R.3    Farooq, S.4    Abbas, F.5
  • 5
    • 0035839126 scopus 로고    scopus 로고
    • Epigenetic reprogramming in mammalian development
    • Reik W., Dean W., and Walter J. Epigenetic reprogramming in mammalian development. Science 293 (2001) 1089-1093
    • (2001) Science , vol.293 , pp. 1089-1093
    • Reik, W.1    Dean, W.2    Walter, J.3
  • 6
    • 0023119242 scopus 로고
    • Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development
    • Monk M., Boubelik M., and Lehnert S. Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. Development 99 (1987) 371-382
    • (1987) Development , vol.99 , pp. 371-382
    • Monk, M.1    Boubelik, M.2    Lehnert, S.3
  • 7
    • 0034015438 scopus 로고    scopus 로고
    • CpG-island methylation in aging and cancer
    • Issa J.P. CpG-island methylation in aging and cancer. Curr Top Microbiol Immunol 249 (2000) 101-118
    • (2000) Curr Top Microbiol Immunol , vol.249 , pp. 101-118
    • Issa, J.P.1
  • 8
    • 34548757364 scopus 로고    scopus 로고
    • Epigenetic reprogramming and imprinting in origins of disease
    • Tang W.Y., and Ho S.M. Epigenetic reprogramming and imprinting in origins of disease. Rev Endocr Metab Disord 8 (2007) 173-182
    • (2007) Rev Endocr Metab Disord , vol.8 , pp. 173-182
    • Tang, W.Y.1    Ho, S.M.2
  • 9
    • 33750244045 scopus 로고    scopus 로고
    • Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder
    • Abdolmaleky H.M., Cheng K.H., Faraone S.V., Wilcox M., Glatt S.J., Gao F., et al. Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Hum Mol Genet 15 (2006) 3132-3145
    • (2006) Hum Mol Genet , vol.15 , pp. 3132-3145
    • Abdolmaleky, H.M.1    Cheng, K.H.2    Faraone, S.V.3    Wilcox, M.4    Glatt, S.J.5    Gao, F.6
  • 10
    • 0035096761 scopus 로고    scopus 로고
    • Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients
    • Deng C., Kaplan M.J., Yang J., Ray D., Zhang Z., McCune W.J., et al. Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. Arthritis Rheum 44 (2001) 397-407
    • (2001) Arthritis Rheum , vol.44 , pp. 397-407
    • Deng, C.1    Kaplan, M.J.2    Yang, J.3    Ray, D.4    Zhang, Z.5    McCune, W.J.6
  • 11
    • 14044252235 scopus 로고    scopus 로고
    • Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3
    • Samaco R.C., Hogart A., and LaSalle J.M. Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3. Hum Mol Genet 14 (2005) 483-492
    • (2005) Hum Mol Genet , vol.14 , pp. 483-492
    • Samaco, R.C.1    Hogart, A.2    LaSalle, J.M.3
  • 12
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg A.P., and Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301 (1983) 89-92
    • (1983) Nature , vol.301 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 13
    • 23044514626 scopus 로고    scopus 로고
    • Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
    • Weber M., Davies J.J., Wittig D., Oakeley E.J., Haase M., Lam W.L., et al. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet 37 (2005) 853-862
    • (2005) Nat Genet , vol.37 , pp. 853-862
    • Weber, M.1    Davies, J.J.2    Wittig, D.3    Oakeley, E.J.4    Haase, M.5    Lam, W.L.6
  • 14
    • 4143140030 scopus 로고    scopus 로고
    • A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors
    • Fraga M.F., Herranz M., Espada J., Ballestar E., Paz M.F., Ropero S., et al. A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors. Cancer Res 64 (2004) 5527-5534
    • (2004) Cancer Res , vol.64 , pp. 5527-5534
    • Fraga, M.F.1    Herranz, M.2    Espada, J.3    Ballestar, E.4    Paz, M.F.5    Ropero, S.6
  • 15
    • 23744461983 scopus 로고    scopus 로고
    • Transposons reanimated in mice
    • Bestor T.H. Transposons reanimated in mice. Cell 122 (2005) 322-325
    • (2005) Cell , vol.122 , pp. 322-325
    • Bestor, T.H.1
  • 17
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • Eden A., Gaudet F., Waghmare A., and Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300 (2003) 455
    • (2003) Science , vol.300 , pp. 455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3    Jaenisch, R.4
  • 18
    • 0024365892 scopus 로고
    • Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
    • Greger V., Passarge E., Hopping W., Messmer E., and Horsthemke B. Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum Genet 83 (1989) 155-158
    • (1989) Hum Genet , vol.83 , pp. 155-158
    • Greger, V.1    Passarge, E.2    Hopping, W.3    Messmer, E.4    Horsthemke, B.5
  • 19
    • 0028875205 scopus 로고
    • Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta M., Bender C.M., Yang A.S., Nguyen T., Beart R.W., Van Tornout J.M., et al. Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res 55 (1995) 4531-4535
    • (1995) Cancer Res , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3    Nguyen, T.4    Beart, R.W.5    Van Tornout, J.M.6
  • 20
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman J.G., and Baylin S.B. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349 (2003) 2042-2054
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 21
    • 0032894125 scopus 로고    scopus 로고
    • Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients
    • Esteller M., Sanchez-Cespedes M., Rosell R., Sidransky D., Baylin S.B., and Herman J.G. Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. Cancer Res 59 (1999) 67-70
    • (1999) Cancer Res , vol.59 , pp. 67-70
    • Esteller, M.1    Sanchez-Cespedes, M.2    Rosell, R.3    Sidransky, D.4    Baylin, S.B.5    Herman, J.G.6
  • 22
    • 0035430440 scopus 로고    scopus 로고
    • Hypermethylation of p16(INK4a) and p15(INK4b) genes in non-small cell lung cancer
    • Kurakawa E., Shimamoto T., Utsumi K., Hirano T., Kato H., and Ohyashiki K. Hypermethylation of p16(INK4a) and p15(INK4b) genes in non-small cell lung cancer. Int J Oncol 19 (2001) 277-281
    • (2001) Int J Oncol , vol.19 , pp. 277-281
    • Kurakawa, E.1    Shimamoto, T.2    Utsumi, K.3    Hirano, T.4    Kato, H.5    Ohyashiki, K.6
  • 23
    • 0346888541 scopus 로고    scopus 로고
    • Hypermethylation of p16INK4a in Chinese lung cancer patients: biological and clinical implications
    • Liu Y., An Q., Li L., Zhang D., Huang J., Feng X., et al. Hypermethylation of p16INK4a in Chinese lung cancer patients: biological and clinical implications. Carcinogenesis 24 (2003) 1897-1901
    • (2003) Carcinogenesis , vol.24 , pp. 1897-1901
    • Liu, Y.1    An, Q.2    Li, L.3    Zhang, D.4    Huang, J.5    Feng, X.6
  • 24
    • 0036157647 scopus 로고    scopus 로고
    • Tumor p16M is a possible marker of advanced stage in non-small cell lung cancer
    • Ng C.S., Zhang J., Wan S., Lee T.W., Arifi A.A., Mok T., et al. Tumor p16M is a possible marker of advanced stage in non-small cell lung cancer. J Surg Oncol 79 (2002) 101-106
    • (2002) J Surg Oncol , vol.79 , pp. 101-106
    • Ng, C.S.1    Zhang, J.2    Wan, S.3    Lee, T.W.4    Arifi, A.A.5    Mok, T.6
  • 25
    • 0035866393 scopus 로고    scopus 로고
    • DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells
    • Jahr S., Hentze H., Englisch S., Hardt D., Fackelmayer F.O., Hesch R.D., et al. DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res 61 (2001) 1659-1665
    • (2001) Cancer Res , vol.61 , pp. 1659-1665
    • Jahr, S.1    Hentze, H.2    Englisch, S.3    Hardt, D.4    Fackelmayer, F.O.5    Hesch, R.D.6
  • 26
    • 0034748725 scopus 로고    scopus 로고
    • DNA-based detection of prostate cancer in blood, urine, and ejaculates
    • Goessl C., Muller M., Heicappell R., Krause H., and Miller K. DNA-based detection of prostate cancer in blood, urine, and ejaculates. Ann N Y Acad Sci 945 (2001) 51-58
    • (2001) Ann N Y Acad Sci , vol.945 , pp. 51-58
    • Goessl, C.1    Muller, M.2    Heicappell, R.3    Krause, H.4    Miller, K.5
  • 27
    • 0033870263 scopus 로고    scopus 로고
    • Genetic analysis of DNA excreted in urine: a new approach for detecting specific genomic DNA sequences from cells dying in an organism
    • Botezatu I., Serdyuk O., Potapova G., Shelepov V., Alechina R., Molyaka Y., et al. Genetic analysis of DNA excreted in urine: a new approach for detecting specific genomic DNA sequences from cells dying in an organism. Clin Chem 46 (2000) 1078-1084
    • (2000) Clin Chem , vol.46 , pp. 1078-1084
    • Botezatu, I.1    Serdyuk, O.2    Potapova, G.3    Shelepov, V.4    Alechina, R.5    Molyaka, Y.6
  • 28
    • 0037089460 scopus 로고    scopus 로고
    • Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers
    • Belinsky S.A., Palmisano W.A., Gilliland F.D., Crooks L.A., Divine K.K., Winters S.A., et al. Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. Cancer Res 62 (2002) 2370-2377
    • (2002) Cancer Res , vol.62 , pp. 2370-2377
    • Belinsky, S.A.1    Palmisano, W.A.2    Gilliland, F.D.3    Crooks, L.A.4    Divine, K.K.5    Winters, S.A.6
  • 29
    • 0033577058 scopus 로고    scopus 로고
    • Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer
    • Ahrendt S.A., Chow J.T., Xu L.H., Yang S.C., Eisenberger C.F., Esteller M., et al. Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer. J Natl Cancer Inst 91 (1999) 332-339
    • (1999) J Natl Cancer Inst , vol.91 , pp. 332-339
    • Ahrendt, S.A.1    Chow, J.T.2    Xu, L.H.3    Yang, S.C.4    Eisenberger, C.F.5    Esteller, M.6
  • 30
    • 18844470774 scopus 로고    scopus 로고
    • Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR
    • Evron E., Dooley W.C., Umbricht C.B., Rosenthal D., Sacchi N., Gabrielson E., et al. Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR. Lancet 357 (2001) 1335-1336
    • (2001) Lancet , vol.357 , pp. 1335-1336
    • Evron, E.1    Dooley, W.C.2    Umbricht, C.B.3    Rosenthal, D.4    Sacchi, N.5    Gabrielson, E.6
  • 32
    • 11144356831 scopus 로고    scopus 로고
    • Methylation changes in faecal DNA: a marker for colorectal cancer screening?
    • Muller H.M., Oberwalder M., Fiegl H., Morandell M., Goebel G., Zitt M., et al. Methylation changes in faecal DNA: a marker for colorectal cancer screening?. Lancet 363 (2004) 1283-1285
    • (2004) Lancet , vol.363 , pp. 1283-1285
    • Muller, H.M.1    Oberwalder, M.2    Fiegl, H.3    Morandell, M.4    Goebel, G.5    Zitt, M.6
  • 33
    • 0035116695 scopus 로고    scopus 로고
    • Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients
    • Rosas S.L., Koch W., da Costa Carvalho M.G., Wu L., Califano J., Westra W., et al. Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients. Cancer Res 61 (2001) 939-942
    • (2001) Cancer Res , vol.61 , pp. 939-942
    • Rosas, S.L.1    Koch, W.2    da Costa Carvalho, M.G.3    Wu, L.4    Califano, J.5    Westra, W.6
  • 34
    • 0036184754 scopus 로고    scopus 로고
    • Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients
    • Chan M.W., Chan L.W., Tang N.L., Tong J.H., Lo K.W., Lee T.L., et al. Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients. Clin Cancer Res 8 (2002) 464-470
    • (2002) Clin Cancer Res , vol.8 , pp. 464-470
    • Chan, M.W.1    Chan, L.W.2    Tang, N.L.3    Tong, J.H.4    Lo, K.W.5    Lee, T.L.6
  • 38
    • 0026546877 scopus 로고
    • A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
    • Frommer M., McDonald L.E., Millar D.S., Collis C.M., Watt F., Grigg G.W., et al. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci U S A 89 (1992) 1827-1831
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 1827-1831
    • Frommer, M.1    McDonald, L.E.2    Millar, D.S.3    Collis, C.M.4    Watt, F.5    Grigg, G.W.6
  • 39
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: a sensitive and quantitative DNA methylation assay
    • Xiong Z., and Laird P.W. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res 25 (1997) 2532-2534
    • (1997) Nucleic Acids Res , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 41
    • 0035710246 scopus 로고    scopus 로고
    • DNA methylation analysis by MethyLight technology
    • Trinh B.N., Long T.I., and Laird P.W. DNA methylation analysis by MethyLight technology. Methods 25 (2001) 456-462
    • (2001) Methods , vol.25 , pp. 456-462
    • Trinh, B.N.1    Long, T.I.2    Laird, P.W.3
  • 42
    • 84934435969 scopus 로고    scopus 로고
    • Application of microarrays for DNA methylation profiling
    • Schumacher A., Weinhausl A., and Petronis A. Application of microarrays for DNA methylation profiling. Methods Mol Biol 439 (2008) 109-129
    • (2008) Methods Mol Biol , vol.439 , pp. 109-129
    • Schumacher, A.1    Weinhausl, A.2    Petronis, A.3
  • 43
    • 37249026814 scopus 로고    scopus 로고
    • Genome-wide analysis of DNA methylation patterns
    • Zilberman D., and Henikoff S. Genome-wide analysis of DNA methylation patterns. Development 134 (2007) 3959-3965
    • (2007) Development , vol.134 , pp. 3959-3965
    • Zilberman, D.1    Henikoff, S.2
  • 44
    • 3042693554 scopus 로고    scopus 로고
    • Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia
    • Lee S., Hwang K.S., Lee H.J., Kim J.S., and Kang G.H. Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia. Lab Invest 84 (2004) 884-893
    • (2004) Lab Invest , vol.84 , pp. 884-893
    • Lee, S.1    Hwang, K.S.2    Lee, H.J.3    Kim, J.S.4    Kang, G.H.5
  • 45
    • 0033862311 scopus 로고    scopus 로고
    • Late onset and high incidence of colon cancer of the mutator phenotype with hypermethylated hMLH1 gene in women
    • Malkhosyan S.R., Yamamoto H., Piao Z., and Perucho M. Late onset and high incidence of colon cancer of the mutator phenotype with hypermethylated hMLH1 gene in women. Gastroenterology 119 (2000) 598
    • (2000) Gastroenterology , vol.119 , pp. 598
    • Malkhosyan, S.R.1    Yamamoto, H.2    Piao, Z.3    Perucho, M.4
  • 46
    • 9244242523 scopus 로고    scopus 로고
    • Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis
    • Xu X.L., Yu J., Zhang H.Y., Sun M.H., Gu J., Du X., et al. Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World J Gastroenterol 10 (2004) 3441-3454
    • (2004) World J Gastroenterol , vol.10 , pp. 3441-3454
    • Xu, X.L.1    Yu, J.2    Zhang, H.Y.3    Sun, M.H.4    Gu, J.5    Du, X.6
  • 47
    • 57349143400 scopus 로고    scopus 로고
    • Activated androgen receptor downregulates E-cadherin gene expression and promotes tumor metastasis
    • Liu Y.N., Liu Y., Lee H.J., Hsu Y.H., and Chen J.H. Activated androgen receptor downregulates E-cadherin gene expression and promotes tumor metastasis. Mol Cell Biol 28 (2008) 7096-7108
    • (2008) Mol Cell Biol , vol.28 , pp. 7096-7108
    • Liu, Y.N.1    Liu, Y.2    Lee, H.J.3    Hsu, Y.H.4    Chen, J.H.5
  • 48
    • 34447100205 scopus 로고    scopus 로고
    • Promoter hypermethylation of TMS1, BRCA1, ERalpha and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients
    • Mirza S., Sharma G., Prasad C.P., Parshad R., Srivastava A., Gupta S.D., et al. Promoter hypermethylation of TMS1, BRCA1, ERalpha and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients. Life Sci 81 (2007) 280-287
    • (2007) Life Sci , vol.81 , pp. 280-287
    • Mirza, S.1    Sharma, G.2    Prasad, C.P.3    Parshad, R.4    Srivastava, A.5    Gupta, S.D.6
  • 49
    • 47949123984 scopus 로고    scopus 로고
    • Promoter hypermethylation of hallmark cancer genes in atypical adenomatous hyperplasia of the lung
    • Licchesi J.D., Westra W.H., Hooker C.M., and Herman J.G. Promoter hypermethylation of hallmark cancer genes in atypical adenomatous hyperplasia of the lung. Clin Cancer Res 14 (2008) 2570-2578
    • (2008) Clin Cancer Res , vol.14 , pp. 2570-2578
    • Licchesi, J.D.1    Westra, W.H.2    Hooker, C.M.3    Herman, J.G.4
  • 50
    • 69949150429 scopus 로고    scopus 로고
    • [Analysis of RASSF1A promoter hypermethylation in serum DNA of non-small cell lung cancer]
    • Yu Z.H., Wang Y.C., Chen L.B., Song Y., Liu C., Xia X.Y., et al. [Analysis of RASSF1A promoter hypermethylation in serum DNA of non-small cell lung cancer]. Zhonghua Zhong Liu Za Zhi 30 (2008) 284-287
    • (2008) Zhonghua Zhong Liu Za Zhi , vol.30 , pp. 284-287
    • Yu, Z.H.1    Wang, Y.C.2    Chen, L.B.3    Song, Y.4    Liu, C.5    Xia, X.Y.6
  • 53
    • 0142153982 scopus 로고    scopus 로고
    • Profiling aberrant DNA methylation in hematologic neoplasms: a view from the tip of the iceberg
    • Esteller M. Profiling aberrant DNA methylation in hematologic neoplasms: a view from the tip of the iceberg. Clin Immunol 109 (2003) 80-88
    • (2003) Clin Immunol , vol.109 , pp. 80-88
    • Esteller, M.1
  • 54
    • 9444266573 scopus 로고    scopus 로고
    • Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells
    • Ropero S., Setien F., Espada J., Fraga M.F., Herranz M., Asp J., et al. Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells. Hum Mol Genet 13 (2004) 2753-2765
    • (2004) Hum Mol Genet , vol.13 , pp. 2753-2765
    • Ropero, S.1    Setien, F.2    Espada, J.3    Fraga, M.F.4    Herranz, M.5    Asp, J.6
  • 55
    • 58849121489 scopus 로고    scopus 로고
    • [Id4 gene methylation for detection of minimal residual disease in acute leukemia]
    • Zhao Y., Yu L., Wang Q.S., Li H.H., Bo J., Wang S.H., et al. [Id4 gene methylation for detection of minimal residual disease in acute leukemia]. Zhonghua Xue Ye Xue Za Zhi 27 (2006) 298-301
    • (2006) Zhonghua Xue Ye Xue Za Zhi , vol.27 , pp. 298-301
    • Zhao, Y.1    Yu, L.2    Wang, Q.S.3    Li, H.H.4    Bo, J.5    Wang, S.H.6
  • 56
    • 9144229469 scopus 로고    scopus 로고
    • Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas
    • Gallardo F., Esteller M., Pujol R.M., Costa C., Estrach T., and Servitje O. Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas. Haematologica 89 (2004) 1401-1403
    • (2004) Haematologica , vol.89 , pp. 1401-1403
    • Gallardo, F.1    Esteller, M.2    Pujol, R.M.3    Costa, C.4    Estrach, T.5    Servitje, O.6
  • 57
    • 21244458051 scopus 로고    scopus 로고
    • Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73
    • van Doorn R., Zoutman W.H., Dijkman R., de Menezes R.X., Commandeur S., Mulder A.A., et al. Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73. J Clin Oncol 23 (2005) 3886-3896
    • (2005) J Clin Oncol , vol.23 , pp. 3886-3896
    • van Doorn, R.1    Zoutman, W.H.2    Dijkman, R.3    de Menezes, R.X.4    Commandeur, S.5    Mulder, A.A.6
  • 58
    • 52549088093 scopus 로고    scopus 로고
    • Promoter hypermethylation in tumour suppressor genes shows association with stage, grade and invasiveness of bladder cancer
    • Jarmalaite S., Jankevicius F., Kurgonaite K., Suziedelis K., Mutanen P., and Husgafvel-Pursiainen K. Promoter hypermethylation in tumour suppressor genes shows association with stage, grade and invasiveness of bladder cancer. Oncology 75 (2008) 145-151
    • (2008) Oncology , vol.75 , pp. 145-151
    • Jarmalaite, S.1    Jankevicius, F.2    Kurgonaite, K.3    Suziedelis, K.4    Mutanen, P.5    Husgafvel-Pursiainen, K.6
  • 59
    • 0028072991 scopus 로고
    • Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
    • Herman J.G., Latif F., Weng Y., Lerman M.I., Zbar B., Liu S., et al. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc Natl Acad Sci U S A 91 (1994) 9700-9704
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 9700-9704
    • Herman, J.G.1    Latif, F.2    Weng, Y.3    Lerman, M.I.4    Zbar, B.5    Liu, S.6
  • 60
    • 33847386223 scopus 로고    scopus 로고
    • Promoter hypermethylation of GSTP1, AR, and 14-3-3sigma in serum of prostate cancer patients and its clinical relevance
    • Reibenwein J., Pils D., Horak P., Tomicek B., Goldner G., Worel N., et al. Promoter hypermethylation of GSTP1, AR, and 14-3-3sigma in serum of prostate cancer patients and its clinical relevance. Prostate 67 (2007) 427-432
    • (2007) Prostate , vol.67 , pp. 427-432
    • Reibenwein, J.1    Pils, D.2    Horak, P.3    Tomicek, B.4    Goldner, G.5    Worel, N.6
  • 61
    • 0036257349 scopus 로고    scopus 로고
    • Genetic status of cell cycle regulators in squamous cell carcinoma of the oesophagus: the CDKN2A (p16(INK4a) and p14(ARF)) and p53 genes are major targets for inactivation
    • Smeds J., Berggren P., Ma X., Xu Z., Hemminki K., and Kumar R. Genetic status of cell cycle regulators in squamous cell carcinoma of the oesophagus: the CDKN2A (p16(INK4a) and p14(ARF)) and p53 genes are major targets for inactivation. Carcinogenesis 23 (2002) 645-655
    • (2002) Carcinogenesis , vol.23 , pp. 645-655
    • Smeds, J.1    Berggren, P.2    Ma, X.3    Xu, Z.4    Hemminki, K.5    Kumar, R.6
  • 63
    • 52149102033 scopus 로고    scopus 로고
    • Methylation of tumor associated genes in tissue and plasma samples from liver disease patients
    • Chang H., Yi B., Li L., Zhang H.Y., Sun F., Dong S.Q., et al. Methylation of tumor associated genes in tissue and plasma samples from liver disease patients. Exp Mol Pathol 85 (2008) 96-100
    • (2008) Exp Mol Pathol , vol.85 , pp. 96-100
    • Chang, H.1    Yi, B.2    Li, L.3    Zhang, H.Y.4    Sun, F.5    Dong, S.Q.6
  • 66
    • 0033558192 scopus 로고    scopus 로고
    • Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers
    • Bachman K.E., Herman J.G., Corn P.G., Merlo A., Costello J.F., Cavenee W.K., et al. Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers. Cancer Res 59 (1999) 798-802
    • (1999) Cancer Res , vol.59 , pp. 798-802
    • Bachman, K.E.1    Herman, J.G.2    Corn, P.G.3    Merlo, A.4    Costello, J.F.5    Cavenee, W.K.6
  • 67
    • 23944463325 scopus 로고    scopus 로고
    • Distinct CpG methylation profiles characterize different clinical groups of neuroblastic tumors
    • Banelli B., Gelvi I., Di Vinci A., Scaruffi P., Casciano I., Allemanni G., et al. Distinct CpG methylation profiles characterize different clinical groups of neuroblastic tumors. Oncogene 24 (2005) 5619-5628
    • (2005) Oncogene , vol.24 , pp. 5619-5628
    • Banelli, B.1    Gelvi, I.2    Di Vinci, A.3    Scaruffi, P.4    Casciano, I.5    Allemanni, G.6
  • 68
    • 0034109902 scopus 로고    scopus 로고
    • Epigenetic silencing of maspin gene expression in human breast cancers
    • Domann F.E., Rice J.C., Hendrix M.J., and Futscher B.W. Epigenetic silencing of maspin gene expression in human breast cancers. Int J Cancer 85 (2000) 805-810
    • (2000) Int J Cancer , vol.85 , pp. 805-810
    • Domann, F.E.1    Rice, J.C.2    Hendrix, M.J.3    Futscher, B.W.4
  • 69
    • 0032403081 scopus 로고    scopus 로고
    • Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells
    • Jarrard D.F., Kinoshita H., Shi Y., Sandefur C., Hoff D., Meisner L.F., et al. Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells. Cancer Res 58 (1998) 5310-5314
    • (1998) Cancer Res , vol.58 , pp. 5310-5314
    • Jarrard, D.F.1    Kinoshita, H.2    Shi, Y.3    Sandefur, C.4    Hoff, D.5    Meisner, L.F.6
  • 73
    • 0035196043 scopus 로고    scopus 로고
    • PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma
    • Salvesen H.B., MacDonald N., Ryan A., Jacobs I.J., Lynch E.D., Akslen L.A., et al. PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma. Int J Cancer 91 (2001) 22-26
    • (2001) Int J Cancer , vol.91 , pp. 22-26
    • Salvesen, H.B.1    MacDonald, N.2    Ryan, A.3    Jacobs, I.J.4    Lynch, E.D.5    Akslen, L.A.6
  • 74
    • 0034721079 scopus 로고    scopus 로고
    • Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia
    • Tsuchiya T., Tamura G., Sato K., Endoh Y., Sakata K., Jin Z., et al. Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia. Oncogene 19 (2000) 3642-3646
    • (2000) Oncogene , vol.19 , pp. 3642-3646
    • Tsuchiya, T.1    Tamura, G.2    Sato, K.3    Endoh, Y.4    Sakata, K.5    Jin, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.