IMP3/L523S, a novel immunocytochemical marker that distinguishes benign and malignant cells: the expression profiles of IMP3/L523S in effusion cytology

Human Pathology

Volumn 41, Issue 5, 2010, Pages 745-750

  Ikeda, Katsuhide ^a   Tate, Genshu ^a   Suzuki, Takao ^a   Kitamura, Takashi ^a   Mitsuya, Toshiyuki ^a  

^a SHOWA UNIVERSITY FUJIGAOKA HOSPITAL   (Japan)

Author keywords

Adenocarcinoma; Effusion cytology; Immunocytochemistry; IMP3 L523S; Malignant mesothelioma

Indexed keywords

MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY IMP3; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ARTICLE; CONTROLLED STUDY; CYTODIAGNOSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MALIGNANT MESOTHELIOMA; MESOTHELIUM CELL; METASTASIS; PERITONEAL DISEASE; PERITONEAL EFFUSION; PLEURA EFFUSION; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY; SQUAMOUS CELL CARCINOMA; TUMOR DIFFERENTIATION;

ADENOCARCINOMA; ASCITIC FLUID; CYTOLOGICAL TECHNIQUES; HUMANS; IMMUNOHISTOCHEMISTRY; MESOTHELIOMA; NEOPLASM PROTEINS; PLEURAL EFFUSION, MALIGNANT; RNA-BINDING PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 77950594482     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2009.04.030     Document Type: Article

References (17)

1. Roberts F., Harper C.M., Downie I., et al. Immunohistochemical analysis still has a limited role in the diagnosis of malignant mesothelioma. Am J Clin Pathol 116 (2001) 253-262
2. Hanley K.Z., Facik M.S., Bourne P.A., et al. Utility of anti-L523S antibody in the diagnosis of benign and malignant serous effusions. Cancer 114 (2008) 49-56
3. Burd C.G., and Dreyfuss G. Conserved structures and diversity of functions of RNA-binding proteins. Science 29 (1994) 615-621
4. Kiledjian M., Wang X., and Liebhaber S.A. Identification of KH domain proteins in the alpha-globin mRNP stability complex. EMBO J 14 (1995) 4357-4364
5. Mueller-Pillasch F., Lacher U., Wallrapp C., et al. Cloning of a gene highly overexpressed in cancer coding for a novel KH-domain containing protein. Oncogene 14 (1997) 2729-2733
6. Nielsen J., Christiansen J., Lykke-Andersen J., et al. A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development. Mol Cell Biol 19 (1999) 1262-1270
7. Yantiss R.K., Woda B.A., Fanger G.R., et al. KOC (K homology domain containing protein overexpressed in cancer): a novel molecular marker that distinguishes between benign and malignant lesions of the pancreas. Am J Surg Pathol 29 (2005) 188-195
8. Istvanic S., Fanger G.R., Fraire A.E., et al. Spectrum of KOC (K homology domain containing protein overexpressed in cancer) immunostaining among carcinomas of different sites. Mod Pathol 18 (2005) 298A-299A
9. Mueller F., Bommer M., Lacher U., et al. KOC is a novel molecular indicator of malignancy. Br J Cancer 88 (2003) 699-701
10. Ikeda K., Tate G., Suzuki T., et al. Coordinate expression of cytokeratin 8 and cytokeratin 17 immunohistochemical staining in cervical intraepithelial neoplasia and cervical squamous cell carcinoma: an immunohistochemical analysis and review of the literature. Gynecol Oncol 108 (2008) 598-602
11. Ikeda K., Suzuki T., Tate G., et al. Cytomorphologic features of well-differentiated papillary mesothelioma in peritoneal effusion: a case report. Diagn Cytopathol 36 (2008) 512-515
12. King J.E., Thatcher N., Pickering C.A., et al. Sensitivity and specificity of immunohistochemical markers used in the diagnosis of epithelioid mesothelioma: a detailed systematic analysis using published date. Histopathology 48 (2006) 223-232
13. Kato Y., Tsuta K., Seki K., et al. Immunohistochemical detection of GLUT-1 can discriminate between reactive mesothelium and malignant mesothelioma. Mod Pathol 20 (2007) 215-220
14. Ligato S., Zhao H., Mandich D., et al. KOC (K homology domain containing protein overexpressed in cancer) and S100A4-protein immunoreactivity improves the diagnostic sensitivity of biliary brushing cytology for diagnosing pancreaticobiliary malignancies. Diagn Cytopathol 36 (2008) 561-567
15. Xu H., Bourne P.A., Spaulding B.O., et al. High-grade neuroendocrine carcinomas of the lung express K homology domain containing protein overexpressed in cancer but carcinoid tumors do not. Hum Pathol 38 (2007) 555-563
16. Simon R., Bourne P.A., Yang Q., et al. Extrapulmonary small cell carcinomas express K homology domain containing protein overexpressed in cancer, but carcinoid tumors do not. Hum Pathol 38 (2007) 1178-1183
17. Mueller-Pillasch F., Pohl B., Wilda M., et al. Expression of the highly conserved RNA binding protein KOC in embryogenesis. Mech Dev 88 (1999) 95-99