Synthesis and evaluation of novel biocompatible super-paramagnetic iron oxide nanoparticles as magnetic anticancer drug carrier and fluorescence active label

Journal of Physical Chemistry C

Volumn 114, Issue 13, 2010, Pages 5850-5858

  Shkilnyy, Andriy ^a   Munnier, Emilie ^a   Hervé, Katel ^a   Soucé, Martin ^a   Benoit, Roland ^b   Cohen Jonathan, Simone ^a   Limelette, Patrice ^a,c   Saboungi, Marie Louise ^b   Dubois, Pierre ^a   Chourpa, Igor ^a  

^a UNIVERSITÉ DE TOURS   (France)

^b IFR 135 Imagerie Fonctionnelle   (France)

^c UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE LABELS; AMINE GROUPS; ANTICANCER ACTIVITIES; ANTICANCER DRUG; BIOCOMPATIBLE POLYMER; CANCER CELLS; CELLULAR ENZYMES; CONFOCAL FLUORESCENCE; COVALENT BINDING; CYTOSOLS; CYTOTOXIC; DOXORUBICIN; DRUG CONCENTRATION; DRUG RELEASE; FLUORESCENCE ACTIVITY; FLUORESCENT LABELS; IN-VITRO; IN-VIVO; IRON CONCENTRATIONS; IRON OXIDE NANOPARTICLE; NONDESTRUCTIVE IMAGING; ONE-POT SYNTHESIS; PHARMACOPHORES; PHYSIOLOGICAL PH; SECONDARY AMINES; SPECTRAL IMAGING; SUGAR MOIETY; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES; SYSTEMIC ADMINISTRATION; TARGETED DRUG DELIVERY;

CELLS; DRUG DELIVERY; ETHYLENE; ETHYLENE GLYCOL; FLUOROPHORES; LABELS; MAGNETIC RESONANCE IMAGING; NANOMAGNETICS; NANOPARTICLES; ORGANIC COMPOUNDS; PH EFFECTS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERS; PROTEINS; RESONANCE; SUGAR (SUCROSE); SUPERPARAMAGNETISM; SUSPENSIONS (FLUIDS);

IRON OXIDES;

EID: 77950592858     PISSN: 19327447     EISSN: 19327455     Source Type: Journal    
DOI: 10.1021/jp9112188     Document Type: Article

References (31)

1. Gupta, A. K.; Gupta, M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications Biomaterials 2005, 26 (18) 3995 - 4021
2. Pankhurst, Q. A.; Connolly, J.; Jones, S. K.; Dobson, J. Applications of magnetic nanoparticles in biomedicine J. Phys. D: Appl. Phys. 2003, 36 R167?R181
3. Thunemann, A. F.; Schutt, D.; Kaufner, L.; Pison, U.; Mohwald, H. Maghemite nanoparticles protectively coated with poly(ethylene imine) and poly(ethylene oxide)- block -poly(glutamic acid) Langmuir 2006, 22 (5) 2351 - 2357
4. Liu, S.; Wei, X.; Chu, M.; Peng, J.; Xu, Y. Synthesis and characterization of iron oxide/polymer composite nanoparticles with pendent functional groups Colloids Surf., B 2006, 51 (2) 101 - 106
5. Mornet, S.; Portier, J.; Duguet, E. A method for synthesis and functionalization of ultrasmall superparamagnetic covalent carriers based on maghemite and dextran J. Magn. Magn. Mater. 2005, 293 (2) 127 - 134 (Pubitemid 40608920)
6. Zhang, Y.; Kohler, N.; Zhang, M. Surface modification of superparamagnetic magnetite nanoparticles and their intracellular uptake Biomaterials 2002, 23 (7) 1553 - 1561 (Pubitemid 34158578)
7. 4 nanoparticles for reduced non-specific uptake by macrophage cells Adv. Mater. 2007, 19, 3163 - 3166 (Pubitemid 350044454)
8. 4 particles by precipitation in the presence of PVA at high pH J. Colloid Interface Sci. 1996, 177 (2) 490 - 494 (Pubitemid 26166485)
9. Mahmoudi, M.; Simchi, A.; Imani, M.; Häfeli, U. O. Superparamagnetic iron oxide nanoparticles with rigid cross-linked polyethylene glycol fumarate coating for application in imaging and drug delivery J. Phys. Chem. C 2009, 113, 8124 - 8131
10. Hervé, K.; Douziech-Eyrolles, L.; Munnier, E.; Cohen-Jonathan, S.; Soucé, M.; Marchais, H.; Limelette, P.; Warmont, F.; Saboungi, M. L.; Dubois, P.; Chourpa, I. The development of stable aqueous suspensions of PEGylated SPIONs for biomedical applications Nanotechnology 2008, 19, 465608
11. Tan, M. L.; Choong, P. F. M.; Dass, C. R. Cancer, chitosan nanoparticles and catalytic nucleic acids J. Pharm. Pharmacol. 2009, 61 (1) 3 - 12
12. Couvreur, P.; Kante, B.; Grislain, L.; Roland, M.; Speiser, P. Toxicity of polyalkylcyanoacrylate nanoparticles II: Doxorubicin-loaded nanoparticles J. Pharm. Sci. 1982, 71 (7) 790 - 792
13. Zhang, J.; Misra, R. D. K. Magnetic drug-targeting carrier encapsulated with thermosensitive smart polymer: Core-shell nanoparticle carrier and drug release response Acta Biomater. 2007, 3 (6) 838 - 850 (Pubitemid 47382675)
14. Lee, E. S.; Na, K.; Bae, Y. H. Super pH-sensitive multifunctional polymeric micelle Nano Lett. 2005, 52 (2) 325 - 329 (Pubitemid 40308294)
15. Sethuraman, V. A.; Lee, M. C.; Bae, Y. H. A biodegradable pH-sensitive Micelle system for targeting acidic solid tumors Pharm. Res. 2008, 25 (3) 657 - 666
16. Ko, J.; Park, K.; Kim, Y. S.; Kim, M. S.; Han, J. K.; Kim, K.; Park, R. W.; Kim, I. S.; Song, H. K.; Lee, D. S.; Kwon, I. C. Tumoral acidic extracellular pH targeting of pH-responsive MPEG-poly(α-amino ester) block copolymer micelles for cancer therapy J. Controlled Release 2007, 123 (2) 109 - 115 (Pubitemid 47562136)
17. Alexiou, C.; Arnold, W.; Klein, R. J.; Parak, F. G.; Hulin, P.; Bergemann, C.; Erhardt, W.; Wagenpfeil, S.; Lübbe, A. S. Locoregional cancer treatment with magnetic drug targeting Cancer Res. 2000, 60 (23) 6641 - 6648
18. Lübbe, A. S.; Bergemann, C.; Riess, H.; Schriever, F.; Reichardt, P.; Possinger, K.; Matthias, M.; Dörken, B.; Herrmann, F.; Gürtler, R.; Hohenberger, P.; Haas, N.; Sohr, R.; Sander, B.; Lemke, A. J.; Ohlendorf, D.; Huhnt, W.; Huhn, D. Clinical experiences with magnetic drug targeting: A phase I study with 4′-epidoxorubicin in 14 patients with advanced solid tumors Cancer Res. 1996, 56 (20) 4686 - 4693 (Pubitemid 26338071)
19. Park, S. I.; Lim, J. H.; Hwang, Y. H.; Kim, K. H.; Kim, S. M.; Kim, J. H.; Kim, C. G.; Kim, C. O. In vivo and in vitro antitumor activity of doxorubicin-loaded magnetic fluids Phys. Status Solidi C 2007, 4 (12) 4345 - 4351
20. Munnier, E.; Cohen-Jonathan, S.; Linassier, C.; Douziech-Eyrolles, L.; Marchais, H.; Souc, M.; Herv, K.; Dubois, P.; Chourpa, I. Novel method of doxorubicin-SPION reversible association for magnetic drug targeting Int. J. Pharm. 2008, 363 (1?2) 170 - 176
21. Etrich, T.; Jelinkova, M.; Rihova, B.; Ulbrich, K. New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: Synthesis and preliminary in vitro and in vivo biological properties J. Controlled Release 2001, 73 (1) 89 - 102 (Pubitemid 32406104)
22. Yuan, Q.; Venkatasubramanian, R.; Hein, S.; Misra, R. D. K. A stimulus-responsive magnetic nanoparticle drug carrier: Magnetite encapsulated by chitosan-grafted-copolymer Acta Biomater. 2008, 4 (4) 1024 - 1037
23. Massart, R. Preparation of aqueous magnetic liquids in alkaline and acidic media IEEE Trans. Magn. 1981, 17 (2) 1247 - 1248 (Pubitemid 11497282)
24. Scofield, J. H. Hartree-Slater subshell photoionization cross-sections at 1254and 1487 eV J. Electron Spectrosc. Relat. Phenom. 1976, 8 (2) 129 - 137
25. Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays J. Immunol. Methods 1983, 65 (1?2) 55 - 63 (Pubitemid 14203433)
26. Sharonov, S.; Chourpa, I.; Morjani, H.; Nabiev, I.; Manfait, M.; Feofanov, A. Confocal spectral imaging analysis in studies of the spatial distribution of antitumour drugs within living cancer cells Anal. Chim. Acta 1994, 290 (1?2) 40 - 47 (Pubitemid 24174682)
27. Chourpa, I.; Douziech-Eyrolles, L.; Ngaboni-Okassa, L.; Fouquenet, J. F.; Cohen-Jonathan, S.; Soucé, M.; Marchais, H.; Dubois, P. Molecular composition of iron oxide nanoparticles, precursors for magnetic drug targeting, as characterized by confocal Raman microspectroscopy Analyst 2005, 130 (10) 1395 - 403 (Pubitemid 41508853)
28. 4 Nanocrystals: Spectroscopic observation of aqueous oxidation kinetics J. Phys. Chem. B 2003, 107, 7501 - 7506
29. Tartaj, P.; Morales, M. P.; Veintemillas-Verdaguer, S.; Gonzales-Carreno, T.; Serna, J. C. The preparation of magnetic nanoparticles for applications in biomedicine J. Phys. D: Appl. Phys. 2003, 36 (13) R182 - R196
30. Cumpson, P. J. Angle-resolved XPS and AES: Depth-resolution limits and a general comparison of properties of depth-profile reconstruction methods J. Electron Spectrosc. Relat. Phenom. 1995, 73 (1) 25 - 52
31. Byrne, J. D.; Betancourt, T.; Brannon-Peppas, L. Active targeting schemes for nanoparticle systems in cancer therapeutics Adv. Drug Deliv. Rev. 2008, 60, 1615 - 1626