Involved Field Radiation After Autologous Stem Cell Transplant for Diffuse Large B-Cell Lymphoma in the Rituximab Era

International Journal of Radiation Oncology Biology Physics

Volumn 77, Issue 1, 2010, Pages 79-85

  Biswas, Tithi ^a   Dhakal, Sughosh ^a   Chen, Rui ^a   Hyrien, Ollivier ^a   Bernstein, Steven ^a   Friedberg, Jonathan W ^a   Fisher, Richard I ^a   Liesveld, Jane ^a   Phillips, Gordon ^a   Constine, Louis S ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

ASCT; Diffuse large B cell lymphoma; IFRT; R CHOP; Rituximab

Indexed keywords

ADRIAMYCIN; DIFFUSE LARGE B-CELL LYMPHOMA; DISEASE-SPECIFIC SURVIVALS; HAZARD RATIO; HIGH-DOSE CHEMOTHERAPIES; INVOLVED FIELD; INVOLVED-FIELD RADIATION THERAPY; LOCAL CONTROL; LOCAL FAILURE; MULTI VARIATE ANALYSIS; NON-HODGKIN'S LYMPHOMA; OVERALL SURVIVAL; SELECTION BIAS; STEM CELL; UNIVARIATE ANALYSIS;

CHEMOTHERAPY; DECISION MAKING; DISEASE CONTROL; MULTIVARIANT ANALYSIS; ONCOLOGY; REFRACTORY MATERIALS;

STEM CELLS;

CARBOPLATIN; CARMUSTINE; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; CYTOSINE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE; MELPHALAN; METHYLPREDNISOLONE; PREDNISONE; RITUXIMAB; VINCRISTINE;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; DRUG MEGADOSE; FEMALE; FEVER; FOLLOW UP; HUMAN; LARGE CELL LYMPHOMA; MAJOR CLINICAL STUDY; MALE; NIGHT SWEAT; OVERALL SURVIVAL; PRIORITY JOURNAL; TREATMENT FAILURE; WEIGHT REDUCTION;

ADOLESCENT; ADULT; AGED; ANALYSIS OF VARIANCE; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CYCLOPHOSPHAMIDE; DOXORUBICIN; FOLLOW-UP STUDIES; HUMANS; LYMPHOMA, LARGE B-CELL, DIFFUSE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PREDNISONE; REMISSION INDUCTION; SALVAGE THERAPY; STEM CELL TRANSPLANTATION; SURVIVAL ANALYSIS; TRANSPLANTATION, AUTOLOGOUS; VINCRISTINE; YOUNG ADULT;

EID: 77950579581     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.04.036     Document Type: Article

References (29)

1. Coiffier B., Lepage E., Briere J., et al. CHOP chemotherapy plus Rituximab compared with CHOP alone in elderly patients with diffuse large B-cell lymphoma. N Engl J Med 346 (2002) 235-242
2. Fisher R.I., Gaynor E.R., Dahlberg S., et al. Comparison of a standard regimen (CHOP) with 3 intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma. N Engl J Med 328 (1993) 1002-1006
3. Mink S.A., and Armitage J.O. High dose therapy in lymphomas: A review of the current status of allogeneic and autologous stem cell transplantation in Hodgkin's disease and non-Hodgkin's lymphoma. Oncologist 6 (2001) 247-256
4. Josting A., Sieniawski M., Glossmann J.P., et al. High dose sequential chemotherapy followed by autologous stem cell transplantation in relapsed and refractory aggressive non-Hodgkin's lymphoma: Results of a multicenter phase II study. Ann Oncol 16 (2005) 1359-1365
5. Wadhwa P., Shina D.C., Schenkein D., et al. Should involved field radiation therapy be used as an adjunct to lymphoma autotransplantation?. Bone Marrow Transplant 29 (2002) 183-189
6. Dawson L.A., Saito N.G., Ratanatharathorn V., et al. Phase I study of involved field radiotherapy preceding autologous stem cell transplantation for patients with high risk lymphoma or Hodgkin's disease. Int J Radiat Oncol Biol Phys 59 (2004) 208-218
7. Mundt A., Williams S.F., and Hallahan D. High dose chemotherapy and stem cell rescue for aggressive non-Hodgkin's lymphoma: Pattern of failure and implications for involved field radiotherapy. Int J Radiat Oncol Biol Phys 39 (1997) 617-625
8. Rapoport A.P., Lifton R., Constine L.S., et al. Autotransplantation for relapsed or refractory non-Hodgkin's lymphoma (NHL): Long-term follow-up and analysis of prognostic factors. Bone Marrow Transplant 19 (1997) 883-890
9. Vose J.M., Link B.K., Grossbard M.L., et al. Phase II study of Rituximab in combination with CHOP chemotherapy in patients with previously untreated, aggressive non-Hodgkin's lymphoma. J Clin Oncol 19 (2001) 389-397
10. Biswas T., Dhakal S., Chawla S., et al. Involved field radiotherapy following autologous stem cell rescue for Hodgkin and non-Hodgkin's lymphoma-is it efficacious?. Int J Radiat Oncol Biol Phys 66 (2006) 499
11. Miller T.P., Dahlberg S., Cassady J.R., et al. Chemotherapy alone compared with chemotherapy plus radiotherapy for localized intermediate and high grade non-Hodgkin's lymphoma. N Engl J Med 339 (1998) 21-26
12. Horning S.J., Weller E., Kim K.M., et al. Chemotherapy with or without radiotherapy in limited-stage diffuse aggressive non-Hodgkin's lymphoma: Eastern Cooperative Oncology Group Study 1484. J Clin Oncol 22 (2004) 3032-3038
13. Miller T., LeBlanc M., Spier C., et al. CHOP alone compared to CHOP plus radiotherapy for early stage aggressive non-Hodgkin's lymphomas: Update of the Southwest Oncology Group (SWOG) randomized trial. Blood 98 (2001) 724a
14. Sehn L.H., Donaldson J., Chhanabhai M., et al. Introduction of combined CHOP plus Rituximab therapy dramatically improved outcome of diffuse large B-cell lymphoma in British Columbia. J Clin Oncol 23 (2005) 5027-5033
15. Habermann T.M., Weller E.A., Morrison V.A., et al. Rituximab-CHOP versus CHOP alone or with maintenance Rituximab in older patients with diffuse large B-cell lymphoma. J Clin Oncol 24 (2006) 3121-3127
16. Pfreundschuh M., Trumper L., Osterborg A., et al. CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large B-cell lymphoma: a randomized controlled trial by the MabThera International Trial (MInT) Group. Lancet Oncol 7 (2006) 379-391
17. Pfreundschuh M., Schubert J., Ziepert M., et al. Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+ B-cell lymphomas: a randomised controlled trial (RICOVER-60). Lancet Oncol 9 (2008) 105-116
18. Persky D.O., Unger J.M., Spier C.M., et al. Phase II study of Rituximab plus three cycles of CHOP and involved field radiotherapy for patients with limited stage aggressive B-cell lymphoma: Southwest Oncology Group Study 0014. J Clin Oncol 26 (2008) 2258-2263
19. Philip T., Gugliemi C., Hagenbeek A., et al. Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin's lymphoma. N Engl J Med 333 (1995) 1540-1545
20. Vose J.M., Bierman P.J., Anderson J.R., et al. Progressive disease after high-dose therapy and autologous transplantation for lymphoid malignancy: clinical course and patient follow-up. Blood 80 (1992) 2142-2148
21. Brasacchio R., Constine L., Rapoport A., et al. Involved field radiotherapy following autotransplantation for lymphoma and Hodgkin's disease. Int J Radiat Oncol Biol Phys 30 (1990) 266
22. Vose J.M., Zhang M.J., Rowlings P.A., et al. Autologous bone marrow transplantation for diffuse aggressive non-Hodgkin's lymphoma in patients never achieving remission: A report from the Autologous Blood and Marrow Transplant Registry. J Clin Oncol 19 (2001) 406-413
23. Kewalramani T., Zelenetz A.D., Hedrick E.E., et al. High-dose chemoradiotherapy and autologous stem cell transplantation for patients with primary refractory aggressive non-Hodgkin lymphoma: An intention-to-treat analysis. Blood 96 (2000) 2399-2404
24. Wendland M., Smith D., Boucher K., et al. The impact of involved field radiation therapy in the treatment of relapsed or refractory non-Hodgkin lymphoma with high-dose chemotherapy followed by hematopoietic progenitor cell transplant. A m J Clin Oncol 30 (2007) 156-162
25. Friedberg J.W., Neuberg D., Monson F., et al. The impact of external beam radiotherapy prior to autologous bone marrow transplantation in patients with non-Hodgkin's lymphoma. Biol Blood Marrow Transplant 7 (2001) 446-453
26. Tsang R.W., Gospodarowicz M.K., Sutcliffe S.B., et al. Thoracic radiation therapy before autologous bone marrow transplantation in relapsed or refractory Hodgkin's disease. Eur J Cancer 35 (1999) 73-78
27. Philip T., Armitage J.O., Spitzer G., et al. High dose therapy and autologous bone marrow transplantation after failure of conventional chemotherapy in adults with intermediate-grade or high-grade non-Hodgkin's lymphoma. N Engl J Med 316 (1987) 1493-1498
28. Hoppe B.S., Moskowitz C.H., Filippa D.A., et al. Involved-field radiotherapy before high-dose therapy and autologous stem-cell rescue in diffuse large-cell lymphoma: long term disease control and toxicity. J Clin Oncol 26 (2008) 1-7
29. Hoppe B.S., Moskowitz C.H., Zhang Z., et al. The role of FDG-PET imaging and involved field radiotherapy in relapsed or refractory diffuse large B-cell lymphoma. Bone Marrow Transplant (2009). Epub ahead of print doi:10.1038/bmt.2008.408