메뉴 건너뛰기




Volumn 89, Issue 5, 2010, Pages 475-482

Clinical efficacy of a bortezomib, cyclophosphamide, thalidomide, and dexamethasone (Vel-CTD) regimen in patients with relapsed or refractory multiple myeloma: A phase II study

Author keywords

Bortezomib; Multiple myeloma; Refractory; Relapse; Thalidomide

Indexed keywords

BORTEZOMIB; CYCLOPHOSPHAMIDE; DEXAMETHASONE; THALIDOMIDE; ANTINEOPLASTIC AGENT; BORONIC ACID DERIVATIVE; PYRAZINE DERIVATIVE;

EID: 77950563131     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00277-009-0856-x     Document Type: Article
Times cited : (41)

References (30)
  • 1
    • 6944235003 scopus 로고    scopus 로고
    • Drug therapy: Multiple myeloma
    • DOI 10.1056/NEJMra041875
    • RA Kyle SV Rajkumar 2004 Multiple myeloma N Engl J Med 351 1860 1873 10.1056/NEJMra041875 1:CAS:528:DC%2BD2cXptFChtLk%3D 15509819 (Pubitemid 39426321)
    • (2004) New England Journal of Medicine , vol.351 , Issue.18
    • Kyle, R.A.1    Rajkumar, S.V.2
  • 2
    • 0014331306 scopus 로고
    • A progress report on the Medical Research Council's therapeutic trial in myelomatosis
    • 10.1111/j.1365-2141.1968.tb01542.x 1:STN:280:DyaF1M%2FjtFyjtw%3D%3D 5696221
    • DA Galton R Peto 1968 A progress report on the Medical Research Council's therapeutic trial in myelomatosis Br J Haematol 15 319 320 10.1111/j.1365-2141. 1968.tb01542.x 1:STN:280:DyaF1M%2FjtFyjtw%3D%3D 5696221
    • (1968) Br J Haematol , vol.15 , pp. 319-320
    • Galton, D.A.1    Peto, R.2
  • 3
    • 1642374858 scopus 로고    scopus 로고
    • Multiple myeloma
    • DOI 10.1016/S0140-6736(04)15736-X, PII S014067360415736X
    • B Sirohi R Powles 2004 Multiple myeloma Lancet 363 875 887 10.1016/S0140-6736(04)15736-X 15031034 (Pubitemid 38368839)
    • (2004) Lancet , vol.363 , Issue.9412 , pp. 875-887
    • Sirohi, B.1    Powles, R.2
  • 4
    • 0025064260 scopus 로고
    • VAD-based regimens as primary treatment for multiple myeloma
    • DOI 10.1002/ajh.2830330203
    • R Alexanian B Barlogie S Tucker 1990 VAD-based regimens as primary treatment for multiple myeloma Am J Hematol 33 86 89 10.1002/ajh.2830330203 1:STN:280:DyaK3c7ksVKquw%3D%3D 2301376 (Pubitemid 20040083)
    • (1990) American Journal of Hematology , vol.33 , Issue.2 , pp. 86-89
    • Alexanian, R.1    Barlogie, B.2    Tucker, S.3
  • 5
    • 0032929769 scopus 로고    scopus 로고
    • Total therapy with tandem transplants for newly diagnosed multiple myeloma
    • 1:STN:280:DyaK1M%2FotFKjsA%3D%3D 9864146
    • B Barlogie S Jagannath KR Desikan, et al. 1999 Total therapy with tandem transplants for newly diagnosed multiple myeloma Blood 93 55 65 1:STN:280:DyaK1M%2FotFKjsA%3D%3D 9864146
    • (1999) Blood , vol.93 , pp. 55-65
    • Barlogie, B.1    Jagannath, S.2    Desikan, K.R.3
  • 6
    • 0024357763 scopus 로고
    • Infusion of vincristine and doxorubicin with oral dexamethasone as first-line therapy for multiple myeloma
    • 10.1016/S0140-6736(89)91549-3 1:STN:280:DyaK3c%2FhtlKrsQ%3D%3D 2571813
    • D Samson E Gaminara A Newland, et al. 1989 Infusion of vincristine and doxorubicin with oral dexamethasone as first-line therapy for multiple myeloma Lancet 2 882 885 10.1016/S0140-6736(89)91549-3 1:STN:280:DyaK3c%2FhtlKrsQ%3D%3D 2571813
    • (1989) Lancet , vol.2 , pp. 882-885
    • Samson, D.1    Gaminara, E.2    Newland, A.3
  • 7
    • 0032705231 scopus 로고    scopus 로고
    • Complete remission rate and outcome after intensive treatment of 177 patients under 75 years of age with IgG myeloma defining a circumscribed disease entity with a new staging system
    • 10.1046/j.1365-2141.1999.01744.x 1:STN:280:DC%2BD3c%2FltVehsw%3D%3D 10583272
    • B Sirohi R Powles J Mehta, et al. 1999 Complete remission rate and outcome after intensive treatment of 177 patients under 75 years of age with IgG myeloma defining a circumscribed disease entity with a new staging system Br J Haematol 107 656 666 10.1046/j.1365-2141.1999.01744.x 1:STN:280: DC%2BD3c%2FltVehsw%3D%3D 10583272
    • (1999) Br J Haematol , vol.107 , pp. 656-666
    • Sirohi, B.1    Powles, R.2    Mehta, J.3
  • 8
    • 0030924408 scopus 로고    scopus 로고
    • Factors influencing collection of peripheral blood progenitor cells following high-dose cyclophosphamide and granulocyte colony stimulating factor in patients with multiple myeloma
    • 10.1046/j.1365-2141.1997.2783095.x 1:STN:280:DyaK2svntlCkuw%3D%3D 9332333
    • H Goldschmidt U Hegenbart M Wallmeier, et al. 1997 Factors influencing collection of peripheral blood progenitor cells following high-dose cyclophosphamide and granulocyte colony stimulating factor in patients with multiple myeloma Br J Haematol 98 736 744 10.1046/j.1365-2141.1997.2783095.x 1:STN:280:DyaK2svntlCkuw%3D%3D 9332333
    • (1997) Br J Haematol , vol.98 , pp. 736-744
    • Goldschmidt, H.1    Hegenbart, U.2    Wallmeier, M.3
  • 9
    • 33947260024 scopus 로고    scopus 로고
    • The emerging role of novel therapies for the treatment of relapsed myeloma
    • 1:CAS:528:DC%2BD1cXmtFOru7c%3D 17335684
    • PG Richardson T Hideshima C Mitsiades, et al. 2007 The emerging role of novel therapies for the treatment of relapsed myeloma J Natl Compr Canc Netw 5 149 162 1:CAS:528:DC%2BD1cXmtFOru7c%3D 17335684
    • (2007) J Natl Compr Canc Netw , vol.5 , pp. 149-162
    • Richardson, P.G.1    Hideshima, T.2    Mitsiades, C.3
  • 10
    • 50449086728 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    • 10.1056/NEJMoa0801479 1:CAS:528:DC%2BD1cXhtVGms77K 18753647
    • JF San Miguel R Schlag NK Khuageva, et al. 2008 Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma N Engl J Med 359 906 917 10.1056/NEJMoa0801479 1:CAS:528:DC%2BD1cXhtVGms77K 18753647
    • (2008) N Engl J Med , vol.359 , pp. 906-917
    • San Miguel, J.F.1    Schlag, R.2    Khuageva, N.K.3
  • 16
    • 21344458719 scopus 로고    scopus 로고
    • VTD (Velcade, thalidomide, dexamethasone) as primary therapy for newly diagnosed multiple myeloma
    • LM Wang DM Weber KB Delasalle, et al. 2004 VTD (Velcade, thalidomide, dexamethasone) as primary therapy for newly diagnosed multiple myeloma Blood 104 210a
    • (2004) Blood , vol.104
    • Wang, L.M.1    Weber, D.M.2    Delasalle, K.B.3
  • 19
    • 0000747276 scopus 로고    scopus 로고
    • Thalidomide with dexamethasone for resistant multiple myeloma
    • DM Weber K Rankin M Gavino, et al. 2000 Thalidomide with dexamethasone for resistant multiple myeloma Blood 96 167a
    • (2000) Blood , vol.96
    • Weber, D.M.1    Rankin, K.2    Gavino, M.3
  • 21
    • 85047682765 scopus 로고    scopus 로고
    • The combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is feasible and can be an option for relapsed/refractory multiple myeloma
    • 10.1038/sj.thj.6200150
    • R Garcia-Sanz MI Gonzalez-Fraile M Sierra C Lopez, et al. 2003 The combination of thalidomide, cyclophosphamide and dexamethasone (ThaCyDex) is feasible and can be an option for relapsed/refractory multiple myeloma Hematol J 3 43 48 10.1038/sj.thj.6200150
    • (2003) Hematol J , vol.3 , pp. 43-48
    • Garcia-Sanz, R.1    Gonzalez-Fraile, M.I.2    Sierra, M.3    Lopez, C.4
  • 22
    • 0036909461 scopus 로고    scopus 로고
    • Use of melphalan, thalidomide, and dexamethasone in treatment of refractory and relapsed multiple myeloma
    • DOI 10.1385/MO:19:4:219
    • G Srkalovic P Elson B Trebisky, et al. 2002 Use of melphalan, thalidomide, and dexamethasone in treatment of refractory and relapsed multiple myeloma Med Oncol 19 219 226 10.1385/MO:19:4:219 1:CAS:528: DC%2BD3sXltFKruw%3D%3D 12512915 (Pubitemid 36016012)
    • (2002) Medical Oncology , vol.19 , Issue.4 , pp. 219-226
    • Srkalovic, G.1    Elson, P.2    Trebisky, B.3    Karam, M.A.4    Hussein, M.A.5
  • 25
    • 54249089458 scopus 로고    scopus 로고
    • Analysis of herpes zoster events among bortezomib-treated patients in the phase III APEX study
    • 10.1200/JCO.2007.14.9641 1:CAS:528:DC%2BD1cXhtlSqsb7K 18711175
    • A Chanan-Khan P Sonneveld MW Schuster, et al. 2008 Analysis of herpes zoster events among bortezomib-treated patients in the phase III APEX study J Clin Oncol 26 4784 4790 10.1200/JCO.2007.14.9641 1:CAS:528:DC%2BD1cXhtlSqsb7K 18711175
    • (2008) J Clin Oncol , vol.26 , pp. 4784-4790
    • Chanan-Khan, A.1    Sonneveld, P.2    Schuster, M.W.3
  • 26
    • 57849161431 scopus 로고    scopus 로고
    • The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesis
    • 10.1038/leu.2008.235 1:CAS:528:DC%2BD1cXhsFWjtb7K 18769451
    • E Terpos E Kastritis M Roussou, et al. 2008 The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesis Leukemia 22 2247 2256 10.1038/leu.2008.235 1:CAS:528:DC%2BD1cXhsFWjtb7K 18769451
    • (2008) Leukemia , vol.22 , pp. 2247-2256
    • Terpos, E.1    Kastritis, E.2    Roussou, M.3
  • 27
    • 33947575994 scopus 로고    scopus 로고
    • Bortezomib, melphalan, prednisone, and thalidomide for relapsed multiple myeloma
    • 1:CAS:528:DC%2BD2sXjvVynsrg%3D 17148584
    • A Palumbo MT Ambrosini G Benevolo, et al. 2007 Bortezomib, melphalan, prednisone, and thalidomide for relapsed multiple myeloma Blood 109 2767 2772 1:CAS:528:DC%2BD2sXjvVynsrg%3D 17148584
    • (2007) Blood , vol.109 , pp. 2767-2772
    • Palumbo, A.1    Ambrosini, M.T.2    Benevolo, G.3
  • 29
    • 60649085451 scopus 로고    scopus 로고
    • Bortezomib, low-dose intravenous melphalan, and dexamethasone for patients with relapsed multiple myeloma
    • 10.1111/j.1365-2141.2008.07572.x 1:CAS:528:DC%2BD1MXkt12ntb8%3D 19183191
    • R Popat H Oakervee C Williams, et al. 2009 Bortezomib, low-dose intravenous melphalan, and dexamethasone for patients with relapsed multiple myeloma Br J Haematol 144 887 894 10.1111/j.1365-2141.2008.07572.x 1:CAS:528:DC%2BD1MXkt12ntb8%3D 19183191
    • (2009) Br J Haematol , vol.144 , pp. 887-894
    • Popat, R.1    Oakervee, H.2    Williams, C.3
  • 30
    • 54249122860 scopus 로고    scopus 로고
    • Phase I-II trial of bortezomib plus oral cyclophosphamide and prednisone in relapsed and refractory multiple myeloma
    • 10.1200/JCO.2007.14.2372 1:CAS:528:DC%2BD1cXhtlSqsb7J 18645194
    • DE Reece GP Rodriguez C Chen, et al. 2008 Phase I-II trial of bortezomib plus oral cyclophosphamide and prednisone in relapsed and refractory multiple myeloma J Clin Oncol 26 4777 4783 10.1200/JCO.2007.14.2372 1:CAS:528: DC%2BD1cXhtlSqsb7J 18645194
    • (2008) J Clin Oncol , vol.26 , pp. 4777-4783
    • Reece, D.E.1    Rodriguez, G.P.2    Chen, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.