Selenomethionine or methylseleninic acid inhibits mutagenesis of a reporter gene in mouse bone marrow

Anticancer Research

Volumn 30, Issue 2, 2010, Pages 291-293

  Kumar, Ma Suresh ^a   Pollok, Karen E ^b   Smith, Martin L ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Carboplatin; Cisplatin; DNA repair; Nucleotide excision repair; Selenium

Indexed keywords

CARBOPLATIN; DRUG METABOLITE; METHYLSELENINIC ACID; SELENIUM DERIVATIVE; SELENOMETHIONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIOPHAGE LAMBDA; BONE MARROW; MOUSE; MOUSE STRAIN; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE;

ANIMALS; ANTINEOPLASTIC AGENTS; BONE MARROW; CARBOPLATIN; DNA-BINDING PROTEINS; GENES, REPORTER; MAXIMUM TOLERATED DOSE; METHIONINE; MICE; MICE, KNOCKOUT; MUTAGENESIS; ORGANOSELENIUM COMPOUNDS; SELENOMETHIONINE;

EID: 77950538388     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Fakih MG, Pendyala L, Brady W, Smith PF, Ross ME, Creaven PJ, Badmaev V, Prey JD and Rustum YM: A phase I and pharmacokinetic study of selenomethionine in combination with a fixed dose of irinotecan in solid tumors. Cancer Chemother Pharmacol 62: 499-508, 2008.
2. Cao S, Durrani FA and Rustum YM: Selective modulation of the therapeutic efficacy of anticancer drugs by selenium-containing compounds against human tumor xenografts. Clin Cancer Res 10: 2561-2569, 2004.
3. Sieja K and Talerczyk M: Selenium as an element in the treatment of ovarian cancer in woman receiving chemotherapy. Gynecol Oncol 93: 320-327, 2004.
4. Fakih M, Cao S, Durrani FA and Rustum YM: Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach to the treatment of solid tumors. Clin Colorectal Cancer 5: 132-135, 2005.
5. Fischer JL, Mihelc E, Pollok KE and Smith ML: Chemotherapeutic selectivity conferred by selenium: a role for p53-dependent DNA repair. Mol Cancer Ther 6: 355-361, 2007.
6. Fischer JL, Kumar MA, Day TW, Hardy TM, Hamilton S, Besch-Williford C, Safa AR, Pollok KE and Smith ML: The Xpc gene markedly affects cell survival in mouse bone marrow. Mutagenesis 24: 309-316, 2009.
7. Reid ME, Diffield-Lillico AJ, Slate E, Natarajan N, Turnbull B, Jacobs E, Combs GF Jr, Alberts DS, Clark LC and Marshall JR: The nutritional prevention of cancer: 400 μg per day selenium treatment. Nutr Cancer 60: 155-163, 2008.
8. Ebert R, Ulmer M, Zeck S, Meissner-Weigl J, Schneider D, Stopper H, Schupp N, Kassem M and Jakob F: Selenium supplementation restores the antioxidative capacity and prevents cell damage in bone marrow stromal cells in vitro. Stem Cells 24: 1226-1235, 2006.