Association of the KIR3DS1*013 and KIR3DL1*004 alleles with susceptibility to ankylosing Spondylitis

Arthritis and Rheumatism

Volumn 62, Issue 4, 2010, Pages 1000-1006

  Díaz Peña, Roberto ^a   Vidal Castiñeira, Jose Ramón ^a   Alonso Arias, Rebeca ^a   Suarez Alvarez, Beatriz ^a   Vicario, Jose Luis ^b   Solana, Rafael ^c   Collantes, Eduardo ^c   López Vázquez, Antonio ^a   Martínez Borra, Jesús ^a   López Larrea, Carlos ^a,d  

^a HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^b Regional Transfusion Center   (Spain)

^c UNIVERSITY OF CÓRDOBA   (Spain)

^d Section of Nephrology   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

HLA B ANTIGEN; HLA B27 ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DS1; HLA BW4; HLA-BW4; KIR3DL1 PROTEIN, HUMAN;

ALLOTYPE; ANKYLOSING SPONDYLITIS; ARTICLE; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; NULL ALLELE; OLIGONUCLEOTIDE PROBE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SPAIN; ALLELE; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENETICS; METHODOLOGY; REFERENCE VALUE; RISK;

ALLELES; COHORT STUDIES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HLA-B ANTIGENS; HUMANS; ODDS RATIO; POLYMERASE CHAIN REACTION; RECEPTORS, KIR3DL1; RECEPTORS, KIR3DS1; REFERENCE VALUES; SPONDYLITIS, ANKYLOSING;

EID: 77950534841     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.27332     Document Type: Article

References (14)

1. Brewerton DA, Hart FD, Nicholls A, Caffrey M, James DC, Sturrock RD. Ankylosing spondylitis and HL-A 27. Lancet 1973; 1:904-907
2. Brown MA. Breakthroughs in genetic studies of ankylosing spondylitis. Rheumatology (Oxford) 2008;47:132-137
3. Gonzalez-Roces S, Alvarez MV, Gonzalez S, Dieye A, Makni H, Woodfield DG, et al. HLA-B27 polymorphism and worldwide susceptibility to ankylosing spondylitis. Tissue Antigens 1997;49:116-123 (Pubitemid 27084693)
4. Khakoo SI, Carrington M. KIR and disease: a model system or system of models? Immunol Rev 2006;214:186-201.
5. Kollnberger S, Bird L, Sun MY, Retiere C, Braud VM, McMichael A, et al. Cell-surface expression and immune receptor recognition of HLA-B27 homodimers. Arthritis Rheum 2002;46:2972-2982 (Pubitemid 35315891)
6. Lopez-Larrea C, Blanco-Gelaz MA, Torre-Alonso JC, Bruges Armas J, Suarez-Alvarez B, Pruneda L, et al. Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations. Arthritis Res Ther 2006;8: R101.
7. Diaz-Pena R, Blanco-Gelaz MA, Suarez-Alvarez B, Martinez-Borra J, Lopez-Vazquez A, Alonso-Arias R, et al. Activating KIR genes are associated with ankylosing spondylitis in Asian populations. Hum Immunol 2008;69:437-442
8. Jiao YL, Ma CY, Wang LC, Cui B, Zhang J, You L, et al. Polymorphisms of KIRs gene and HLA-C alleles in patients with ankylosing spondylitis: possible association with susceptibility to the disease. J Clin Immunol 2008;28:343-349
9. Harvey D, Pointon JJ, Sleator C, Meenagh A, Farrar C, Sun JY, et al. Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis. Ann Rheum Dis 2009;68:595-598
10. Pando MJ, Gardiner CM, Gleimer M, McQueen KL, Parham P. The protein made from a common allele of KIR3DL1 (3DL1*004) is poorly expressed at cell surfaces due to substitution at positions 86 in Ig domain 0 and 182 in Ig domain 1. J Immunol 2003;171: 6640-6649 (Pubitemid 37532096)
11. Van der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis: a proposal for modification of the New York criteria. Arthritis Rheum 1984;27:361-368
12. Gomez-Lozano N, Vilches C. Genotyping of human killer-cell immunoglobulin-like receptor genes by polymerase chain reaction with sequence-specific primers: an update. Tissue Antigens 2002; 59:184-193 (Pubitemid 34666561)
13. Halfpenny IA, Middleton D, Barnett YA, Williams F. Investigation of killer cell immunoglobulin-like receptor gene diversity: IV. KIR3DL1/S1. Hum Immunol 2004;65:602-612 (Pubitemid 38813411)
14. Martin MP, Qi Y, Gao X, Yamada E, Martin JN, Pereyra F, et al. Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat Genet 2007;39:733-740 (Pubitemid 46848586)