Translational research in women's health: From bedside to bench and from bench to bedside

International Journal of Gynecology and Obstetrics

Volumn 109, Issue 2, 2010, Pages 83-84

  Maruo, Takeshi ^a  

^a KOBE CHILDREN S HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASOPRISNIL; EPIDERMAL GROWTH FACTOR; LEVONORGESTREL; PROGESTERONE RECEPTOR MODULATOR; ULIPRISNIL ACETATE; UNCLASSIFIED DRUG;

CLINICAL TRIAL; COLLAGEN SYNTHESIS; DRUG ACTIVITY; EDITORIAL; ENDOMETRIUM ABLATION; FEMALE; HUMAN; HYSTERECTOMY; INTRAUTERINE CONTRACEPTIVE DEVICE; LEIOMYOMA; MENORRHAGIA; MENSTRUATION; PRIORITY JOURNAL; UTERUS MYOMA; WOMEN'S HEALTH;

EID: 77950517685     PISSN: 00207292     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijgo.2010.01.003     Document Type: Editorial

References (20)

1. Maruo T., Matsuo H., Samoto T., Shimomura Y., Kurachi O., Gao Z., et al. Effects of progesterone on uterine leiomyoma growth and apoptosis. Steroids 65 10-11 (2000) 585-592
2. Maruo T., Laog-Fernandez J.B., Matsuo H., Samoto T., Kurachi O., Takeuchi S., et al. Effects of LNG-IUS on the endometrium and the relevance to the management of menorrhagia. In: Maruo T., Barlow D., Mardon H., and Kennedy S. (Eds). Cell and Molecular Biology of Endometrium (2002), Soeisha, Osaka 193-207
3. Kriplani A., Singh B.M., Lal S., and Agarwal N. Efficacy, acceptability and side effects of the levonorgestrel intrauterine system for menorrhagia. Int J Gynecol Obstet 97 3 (2007) 190-194
4. Gupta B., Mittal S., Misra R., Deka D., and Dadhwal V. Levonorgestel-releasing intrauterine system vs. transcervical endometrial resection for dysfunctional uterine bleeding. Int J Gynecol Obstet 95 3 (2006) 261-266
5. Maruo T., Laoag-Fernandez J.B., Pakarinen P., Murakoshi H., Spitz I.M., and Johansson E. Effects of the levonorgestrel-releasing intrauterine system on proliferation and apoptosis in the endometrium. Hum Reprod 16 10 (2001) 2103-2108
6. Maruo T., Ohara N., Matsuo H., Xu Q., Chen W., Sitruk-Ware R., et al. Effects of levonorgestrel-releasing IUS and progesterone receptor modulator CDB-2914 on uterine leiomyomas. Contraception 75 6 (2007) S99-S103
7. Shimomura Y., Matsuo H., Samoto T., and Maruo T. Up-regulation by progesterone of proliferating cell nuclear antigen and epidermal growth factor expression in human uterine leiomyoma. J Clin Endocrinol Metab 83 6 (1998) 2192-2198
8. Gao Z., Matsuo H., Wang Y., Nakago S., and Maruo T. Up-regulation by IGF-I of proliferating cell nuclear antigen and Bcl-2 expression in human uterine leiomyoma cells. J Clin Endocrinol Metab 86 11 (2001) 5593-5599
9. Matsuo H., Maruo T., and Samoto T. Increased expression of Bcl-2 protein in human uterine leiomyoma and its up-regulation by progesterone. J Clin Endocrinol Metab 82 1 (1997) 293-299
10. Kurachi O., Matsuo H., Samoto T., and Maruo T. Tumor necrosis factor-alpha expression in uterine leiomyoma and its down-regulation by progesterone. J Clin Endocrinol Metab 86 5 (2001) 2275-2280
11. Xu Q., Takekida S., Ohara N., Chen W., Sitruk-Ware R., Johansson E.D., et al. Progesterone receptor modulator CDB-2914 down-regulates proliferative cell nuclear antigen and Bcl-2 protein expression and up-regulates caspase-3 and poly(adenosine 5′-diphosphate ribose) polymerase expression in cultured human uterine leiomyoma cells. J Clin Endocrinol Metab 90 2 (2005) 953-961
12. Xu Q., Ohara N., Chen W., Liu J., Sasaki H., Morikawa A., et al. Progesterone receptor modulator CDB-2914 down-regulates vascular endothelial growth factor, adrenomedullin and their receptors and modulates progesterone receptor content in cultured human uterine leiomyoma cells. Hum Reprod 21 9 (2006) 2408-2416
13. Maruo T., Ohara N., Wang J., and Matsuo H. Sex steroidal regulation of uterine leiomyoma growth and apoptosis. Hum Reprod Update 10 3 (2004) 207-220
14. Xu Q., Ohara N., Liu J., Amano M., Sitruk-Ware R., Yoshida S., et al. Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells. Mol Hum Reprod 14 3 (2008) 181-191
15. Chen W., Ohara N., Wang J., Xu Q., Liu J., Morikawa A., et al. A novel selective progesterone receptor modulator asoprisnil inhibits proliferation and induces apoptosis in cultured uterine leiomyoma cells. J Clin Endocrinol Metab 91 4 (2006) 1296-1304
16. Wang J., et al. A novel selective progesterone receptor modulator asoprisnil (J867) down-regulates the expression of EGF, IGF-I, TGFbeta3 and their receptors in cultured uterine leiomyoma cells. Hum Reprod 21 7 (2006) 1869-1877
17. Sasaki H., Ohara N., Xu Q., Wang J., DeManno D.A., Chwalisz K., et al. A novel selective progesterone receptor modulator asoprisnil activates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated signaling pathway in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells. J Clin Endocrinol Metab 92 2 (2007) 616-623
18. Morikawa A., Ohara N., Xu Q., Nakabayashi K., DeManno D.A., Chwalisz K., et al. Selective progesterone receptor modulator asoprisnil down-regulates collagen synthesis in cultured human uterine leiomyoma cells through up-regulating extracellular matrix metalloproteinase inducer. Hum Reprod 23 4 (2008) 944-951
19. Ohara N., Xu Q., Matsuo H., and Maruo T. Progesterone and progesterone receptor modulator in uterine leiomyoma growth. In: Maruo T., Mardon H., and Stewart C. (Eds). Translational Research in Uterine Biology (2008), Elsevier, Amsterdam 161-178
20. Lal S., Kriplani A., Kulshrestha V., Sharma M., and Agarwal N. Efficacy of mifepristone in reducing intermenstrual vaginal bleeding in users of the levonorgestrel intrauterine system. Int J Gynecol Obstet 109 2 (2010) 128-130 (this issue)