Severe life threatening neurotoxicity in a child with acute lymphoblastic leukemia receiving posaconazole and vincristine

Pediatric Blood and Cancer

Volumn 54, Issue 5, 2010, Pages 783-

  Jain, Sandeep ^a   Kapoor, Gauri ^a  

^a RAJIV GANDHI CANCER INSTITUTE AND RESEARCH CENTRE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ASPARAGINASE; DAUNORUBICIN; PHENYTOIN; POSACONAZOLE; PREDNISOLONE; VINCRISTINE; ANTIFUNGAL AGENT; ANTINEOPLASTIC AGENT; TRIAZOLE DERIVATIVE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTIFICIAL VENTILATION; CANCER COMBINATION CHEMOTHERAPY; CANCER REGRESSION; CASE REPORT; CHILD; DEBRIDEMENT; DISEASE SEVERITY; DRUG WITHDRAWAL; HUMAN; INAPPROPRIATE VASOPRESSIN SECRETION; LETHARGY; LETTER; LUNG LESION; MALE; MUCORMYCOSIS; NEUROTOXICITY; PRESCHOOL CHILD; PRIORITY JOURNAL; SEIZURE; SERUM OSMOLALITY; SODIUM URINE LEVEL; URINE OSMOLALITY; DRUG COMBINATION; DRUG INTERACTION; TOXICITY AND INTOXICATION;

ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHILD, PRESCHOOL; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; HUMANS; MALE; MUCORMYCOSIS; NEUROTOXICITY SYNDROMES; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; TRIAZOLES; VINCRISTINE;

EID: 77950498239     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.22399     Document Type: Letter

References (4)

1. Hammond IW, Ferguson JA, Kwong K, et al. Hyponatremia and syndrome of inappropriate anti-diuretic hormone reported with the use of vincristine: An over-representation of Asians? Pharmacoepidemiol Drug Saf 2002;11:229-234.
2. Stuart MJ, Cuaso C, Miller M, et al. Syndrome of recurrent increased secretion of antidiuretic hormone following multiple doses of vincristine. Blood 1975;45:315-320.
3. Ce'line E, Gilles P, Dominique H, et al. Posaconazole-increased vincristine neurotoxicity in a child: A case report. J Pediatr Hematol Oncol 2009;31:292-295.
4. Mantadakis E, Amoiridis G, Kondi A, et al. Possible increase of the neurotoxicity of vincristine by the concurrent use of posaconazole in a young adult with leukemia. J Pediatr Hematol Oncol 2007;29:130. (Pubitemid 46213863)