Molecular basis of colorectal cancer

New England Journal of Medicine

Volumn 362, Issue 13, 2010, Pages 1245-1247

  Kouzminova, Natalia ^a   Lu, Tiffany ^a   Lin, Albert Y ^a  

^a SANTA CLARA VALLEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; TUMOR MARKER;

CANCER CHEMOTHERAPY; CHROMOSOME 18Q; COLORECTAL CANCER; HETEROZYGOSITY LOSS; HUMAN; LETTER; MICROSATELLITE INSTABILITY; MOLECULAR MECHANICS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; TREATMENT RESPONSE; CHROMOSOME 18; COLORECTAL TUMOR; GENETIC PREDISPOSITION; GENETICS; NOTE;

CHROMOSOMES, HUMAN, PAIR 18; COLORECTAL NEOPLASMS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE INSTABILITY; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 77950496478     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc1000949     Document Type: Letter

References (4)

1. Markowitz SD, Bertagnolli MM. Molecular basis of colorectal cancer. N Engl J Med 2009;361:2449-60.
2. Ogino S, Nosho K, Irahara N, et al. Prognostic significance and molecular associations of 18q loss of heterozygosity: a cohort study of microsatellite stable colorectal cancers. J Clin Oncol 2009;27:4591-8.
3. Tejpar S, Bosman F, Delorenzi M, et al. Microsatellite instability (MSI) in stage II and III colon cancer treated with 5FU-LV or 5FU-LV and irinotecan (PETACC 3-EORTC 40993-SAKK 60/00 trial). J Clin Oncol 2009; 27: Suppl: 169s. abstract.
4. Kim GP, Colangelo LH, Wieand HS, et al. Prognostic and predictive roles of high-degree m icro satellite instability in colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study. J Clin Oncol 2007;25:767-72.