A probabilistic model for risk assessment of residual host cell DNA in biological products

Vaccine

Volumn 28, Issue 19, 2010, Pages 3308-3311

  Yang, Harry ^a   Zhang, Lanju ^a   Galinski, Mark ^a  

^a MEDIMMUNE   (United States)

Author keywords

DNA oncogenicity; Enzyme inactivation; Host cell DNA; Infectivity; Risk assessment

Indexed keywords

CELL DNA; INFLUENZA VACCINE; LIVE VACCINE; RESIDUAL HOST CELL DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DISEASE MODEL; DRUG PURIFICATION; DRUG SAFETY; ENZYME INACTIVATION; GENETIC RISK; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MATHEMATICAL MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; VIRUS CARCINOGENESIS; VIRUS GENOME; VIRUS INFECTIVITY; VIRUS ONCOGENE;

BIOLOGICAL PRODUCTS; DNA; DRUG CONTAMINATION; HUMANS; MODELS, STATISTICAL; RISK ASSESSMENT;

EID: 77950493967     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.02.099     Document Type: Article

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