Preoperative statin is associated with decreased operative mortality in high risk coronary artery bypass patients

Journal of Cardiothoracic Surgery

Volumn 5, Issue 1, 2010, Pages

  Magovern, James A ^a   Moraca, Robert J ^a   Bailey, Stephen H ^a   Dean, David A ^a   Simpson, Kathleen A ^a   Maher, Thomas D ^a   Benckart, Daniel H ^a   Magovern Jr, George J ^a  

^a ALLEGHENY GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ADULT; AGED; ARTICLE; CHI SQUARE DISTRIBUTION; CORONARY ARTERY BYPASS GRAFT; FEMALE; HUMAN; MALE; MIDDLE AGED; MORTALITY; NONPARAMETRIC TEST; POSTOPERATIVE COMPLICATION; PREOPERATIVE CARE; RETROSPECTIVE STUDY; RISK;

ADULT; AGED; AGED, 80 AND OVER; CHI-SQUARE DISTRIBUTION; CORONARY ARTERY BYPASS; FEMALE; HOSPITAL MORTALITY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PREOPERATIVE CARE; RETROSPECTIVE STUDIES; RISK; STATISTICS, NONPARAMETRIC;

EID: 77950439777     PISSN: None     EISSN: 17498090     Source Type: Journal    
DOI: 10.1186/1749-8090-5-8     Document Type: Article

References (15)

1. Third Report on the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002, 06:3143-3421.
2. Kinlay S, Egido J. Inflammatory biomarkers in stable atherosclerosis. Am J Cardiol 2006, 98(11A):2P-8P. 10.1016/j.amjcard.2006.09.014, 17126676.
3. Walter DH, Rittig K, Bahlmann FH, Kirchmair R, Silver M, Murayama T, Nishimura H, Losordo DW, Asahara T, Isner JM. Statin therapy accelerates re-endothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells. Circulation 2002, 105:3017-3024. 10.1161/01.CIR.0000018166.84319.55, 12081997.
4. Sotirios T. Oxidative biomarkers in the diagnosis and prognosis of cardiovascular disease. Am J Cardiol 2006, 98(11A):9P-17P.
5. Libby P, Sasiela W. Plaque stabilization: can we turn theory into evidence?. Am J Cardiol 2006, 98(11A):26P-33P. 10.1016/j.amjcard.2006.09.017, 17126677.
6. Magovern JA, Sakert T, Magovern GJ, Benckart DH, Burkholder JA, Liebler GA, Magovern GJ. A model that predicts morbidity and mortality after coronary artery bypass graft surgery. J Am Coll Cardiol 1996, 28(5):1147-53. 10.1016/S0735-1097(96)00310-5, 8890808.
7. Nilsson J, Algotsson L, Höglund P, Lührs C, Brandt J. Comparison of 19 pre-operative risk stratification models in open heart surgery. Eur Heart J 2006, 27:867-874. 10.1093/eurheartj/ehi720, 16421172.
8. Clark LL, Ikonomidis JS, Crawford FA, Crumbley A, Kratz JM, Stroud MR, Woolson RF, Bruce JJ, Nicholas JS, Lackland DT, Zile MR, Spinale FG. Preoperative statin treatment is associated with reduced postoperative mortality and morbidity in patients undergoing cardiac surgery: an 8-year retrospective cohort study. J Thorac Cardiovasc Surg 2006, 131:679-85. 10.1016/j.jtcvs.2005.11.006, 16515923.
9. Pan W, Pintar T, Anton J, Lee VV, Vaughn WK, Collard CD. Statins are associated with a reduced incidence of perioperative mortality after coronary artery bypass graft surgery. Circulation 2004, 110:II-45-II-49.
10. Collard CD, Body SC, Shernan SK, Wang S, Mangano DT. Preoperative statin therapy is associated with reduced cardiac mortality after coronary artery bypass graft surgery. J Thorac Cardiovasc Surg 2006, 132:392-400. 10.1016/j.jtcvs.2006.04.009, 16872968.
11. Magovern JA, Singh D, Teekell-Taylor L, Scalise D, McGregor W. Preoperative clinical factors are important determinants of the inflammatory state before and after heart surgery. ASAIO J 2007, 53(3):316-9. 10.1097/MAT.0b013e31804b19f7, 17515721.
12. Podgoreanu MV, White WD, Morris RW, Mathew JP, Stafford-Smith M, Welsby IJ, Grocott HP, Milano CA, Newman MF, Schwinn DA. Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery. Circulation 2006, 114(1 Suppl):I275-I281. 1945056, 16820586.
13. Wright RS, Bybee K, Miller WL, Laudon DA, Murphy JG, Jaffe A. Reduced risks of death and CHF are associated with statin therapy administered acutely within the first 24 hours of AMI. Int J Cardiol 2006, 108:314-319. 10.1016/j.ijcard.2005.05.014, 15975672.
14. Ray KK, Cannon CP, Ganz P. Beyond lipid lowering: what have we learned about statins from the acute coronary syndrome trials. Am J Cardiol 2006, 98(11A):18P-25P. 10.1016/j.amjcard.2006.09.016, 17126675.
15. Tiefenbacher CP, Kapitza J, Dietz V, Lee CH, Niroomand F. Reduction of myocardial infarct size by fluvastatin. Am J Physiol Heart Circ Physiol 2003, 285:H59-64.