Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 12, 2010, Pages 5288-5293

  Horowitz, Eric D ^a   Engelhart, Aaron E ^a   Chen, Michael C ^a   Quarles, Kaycee A ^a   Smith, Michael W ^a   Lynn, David G ^a,b   Hud, Nicholas V ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

Base pair selection; Molecular evolution; Origin of life; Polymerization; RNA world

Indexed keywords

OLIGONUCLEOTIDE; PREBIOTIC AGENT;

ARTICLE; BASE PAIRING; CYCLIZATION; INTERCALATION COMPLEX; MOLECULAR EVOLUTION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

BASE PAIRING; BIOGENESIS; ETHIDIUM; EVOLUTION, MOLECULAR; INTERCALATING AGENTS; MODELS, CHEMICAL; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; RNA; THERMODYNAMICS;

TETRA;

EID: 77950379430     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0914172107     Document Type: Article

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