Relation of Systemic Venous Return, Pulmonary Vascular Resistance, and Diastolic Dysfunction to Exercise Capacity in Patients With Single Ventricle Receiving Fontan Palliation

American Journal of Cardiology

Volumn 105, Issue 8, 2010, Pages 1169-1175

  Goldstein, Bryan H ^a,b   Connor, Chad E ^c   Gooding, Lindsay ^a,b   Rocchini, Albert P ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c WRIGHT PATTERSON AIR FORCE BASE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ANAEROBIC THRESHOLD; ARTICLE; BLOOD PRESSURE; BODY POSTURE; CHILD; CLINICAL ARTICLE; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; DOPPLER ECHOCARDIOGRAPHY; EXERCISE; EXERCISE TEST; FEMALE; FONTAN PROCEDURE; HEART SINGLE VENTRICLE; HEMODYNAMIC PARAMETERS; HUMAN; INDWELLING CATHETER; LUNG VASCULAR RESISTANCE; MALE; OXYGEN CONSUMPTION; OXYGEN SATURATION; PRIORITY JOURNAL; SUPINE POSITION; VENOUS RETURN;

ADOLESCENT; ADULT; CHILD; CROSS-OVER STUDIES; DIASTOLE; ECHOCARDIOGRAPHY, DOPPLER; ELECTROCARDIOGRAPHY; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; FOLLOW-UP STUDIES; FONTAN PROCEDURE; HEART DEFECTS, CONGENITAL; HEART VENTRICLES; HUMANS; MALE; MYOCARDIAL CONTRACTION; OXYGEN CONSUMPTION; PREOPERATIVE PERIOD; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; STROKE VOLUME; TIME FACTORS; VASCULAR RESISTANCE; VENOUS PRESSURE; VENTRICULAR DYSFUNCTION, LEFT; YOUNG ADULT;

EID: 77950371675     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2009.12.020     Document Type: Article

References (30)

1. Terkelsen K.E., Clark A.L., and Hillis W.S. Ventilatory response to erect and supine exercise. Med Sci Sports Exerc 31 (1999) 1429-1432
2. Hughson R.L., Xing H.C., Borkhoff C., and Butler G.C. Kinetics of ventilation and gas exchange during supine and upright cycle exercise. Eur J Appl Physiol Occup Physiol 63 (1991) 300-307
3. Koga S., Shiojiri T., Shibasaki M., Kondo N., Fukuba Y., and Barstow T.J. Kinetics of oxygen uptake during supine and upright heavy exercise. J Appl Physiol 87 (1999) 253-260
4. Kelley J.R., Mack G.W., and Fahey J.T. Diminished venous vascular capacitance in patients with univentricular hearts after the Fontan operation. Am J Cardiol 76 (1995) 158-163
5. Hsia T.Y., Khambadkone S., Redington A.N., Migliavacca F., Deanfield J.E., and de Leval M.R. Effects of respiration and gravity on infradiaphragmatic venous flow in normal and Fontan patients. Circulation 102 (2000) 148-153
6. James F.W., Kaplan S., Glueck C.J., Tsay J.Y., Knight M.J., and Sarwar C.J. Responses of normal children and young adults to controlled bicycle exercise. Circulation 61 (1980) 902-912
7. Beaver W.L., Wasserman K., and Whipp B.J. A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol 60 (1986) 2020-2027
8. Polgar G., and Promadhat V. Pulmonary Function Testing in Children: Technics and Standards (1971), WB Saunders, Philadelphia 42-212
9. Diller G.P., Dimopoulos K., Okonko D., Uebing A., Broberg C.S., Babu-Narayan S., Bayne S., Poole-Wilson P.A., Sutton R., Francis D.P., and Gatzoulis M.A. Heart rate response during exercise predicts survival in adults with congenital heart disease. J Am Coll Cardiol 48 (2006) 1250-1256
10. Washington R.L., van Gundy J.C., Cohen C., Sondheimer H.M., and Wolfe R.R. Normal aerobic and anaerobic exercise data for North American school-age children. J Pediatr 112 (1988) 223-233
11. Rocchini A.P. Hemodynamic abnormalities in response to supine exercise in patients after operative correction of tetrad of Fallot after early childhood. Am J Cardiol 48 (1981) 325-330
12. Driscoll D.J., and Durongpisitkul K. Exercise testing after the Fontan operation. Pediatr Cardiol 20 (1999) 57-59
13. Takken T., Hulzebos H.J., Blank A.C., Tacken M.H.P., Helders P.J.M., and Strengers J.L.M. Exercise prescription for patients with a Fontan circulation: current evidence and future directions. Neth Heart J 15 (2007) 142-147
14. Durongpisitkul K., Driscoll D.J., Mahoney D.W., Wollan P.C., Mottram C.D., Puga F.J., and Danielson G.K. Cardiorespiratory response to exercise after modified Fontan operation: determinants of performance. J Am Coll Cardiol 29 (1997) 785-790
15. Gentles T.L., Gauvreau K., Mayer Jr. J.E., Fishberger S.B., Burnett J., Colan S.D., Newburger J.W., and Wernovsky G. Functional outcome after the Fontan operation: factors influencing late morbidity. J Thorac Cardiovasc Surg 114 (1997) 392-403
16. Jenkins P.C., Chinnock R.E., Jenkins K.J., Mahle W.T., Mulla N., Sharkey A.M., and Flanagan M.F. Decreased exercise performance with age in children with hypoplastic left heart syndrome. J Pediatr 152 (2008) 507-512
17. Zajac A., Tomkiewicz L., Podolec P., Tracz W., and Malec E. Cardiorespiratory response to exercise in children after modified Fontan operation. Scand Cardiovasc J 36 (2002) 80-85
18. Rhodes J., Curran T.J., Camil L., Rabideau N., Fulton D.R., Gauthier N.S., Gauvreau K., and Jenkins K.J. Impact of cardiac rehabilitation on the exercise function of children with serious congenital heart disease. Pediatrics 116 (2005) 1339-1345
19. Paridon S.M., Mitchell P.D., Colan S.D., Williams R.V., Blaufox A., Li J.S., Margossian R., Mital S., Russell J., Rhodes J., and Pediatric Heart Network Investigators. A cross-sectional study of exercise performance during the first 2 decades of life after the Fontan operation. J Am Coll Cardiol 52 (2008) 99-107
20. Gewillig M.H., Lundström U.R., Bull C., Wyse R.K., and Deanfield J.E. Exercise responses in patients with congenital heart disease after Fontan repair: patterns and determinants of performance. J Am Coll Cardiol 15 (1990) 1424-1432
21. Meadows J., Lang P., Marx G., and Rhodes J. Fontan fenestration closure has no acute effect on exercise capacity but improves ventilatory response to exercise. J Am Coll Cardiol 52 (2008) 108-113
22. Giardini A., Balducci A., Specchia S., Gargiulo G., Bonvicini M., and Picchio F.M. Effect of sildenafil on haemodynamic response to exercise and exercise capacity in Fontan patients. Eur Heart J 29 (2008) 1681-1687
23. Uzun O., Wong J.K., Bhole V., and Stumper O. Resolution of protein-losing enteropathy and normalization of mesenteric Doppler flow with sildenafil after Fontan. Ann Thorac Surg 82 (2006) e39-e40
24. Haseyama K., Satomi G., Yasukochi S., Matsui H., Harada Y., and Uchita S. Pulmonary vasodilation therapy with sildenafil citrate in a patient with plastic bronchitis after the Fontan procedure for hypoplastic left heart syndrome. J Thorac Cardiovasc Surg 132 (2006) 1232-1233
25. Guazzi M., Tumminello G., Di Marco F., and Guazzi M.D. Influences of sildenafil on lung function and hemodynamics in patients with chronic heart failure. Clin Pharmacol Ther 76 (2004) 371-378
26. Guazzi M., Tumminello G., Di Marco F., Fiorentini C., and Guazzi M.D. The effects of phosphodiesterase-5 inhibition with sildenafil on pulmonary hemodynamics and diffusion capacity, exercise ventilatory efficiency, and oxygen uptake kinetics in chronic heart failure. J Am Coll Cardiol 44 (2004) 2339-2348
27. Reeves J.T., Linehan J.H., and Stenmark K.R. Distensibility of the normal human lung circulation during exercise. Am J Physiol Lung Cell Mol Physiol 288 (2005) L419-L425
28. Stickland M.K., Welsh R.C., Petersen S.R., Tyberg J.V., Anderson W.D., Jones R.L., Taylor D.A., Bouffard M., and Haykowsky M.J. Does fitness level modulate the cardiovascular hemodynamic response to exercise?. J Appl Physiol 100 (2006) 1895-1901
29. Anderson P.A., Sleeper L.A., Mahony L., Colan S.D., Atz A.M., Breitbart R.E., Gersony W.M., Gallagher D., Geva T., Margossian R., McCrindle B.W., Paridon S., Schwartz M., Stylianou M., Williams R.V., Clark III B.J., and Pediatric Heart Network Investigators. Contemporary outcomes after the Fontan procedure: a Pediatric Heart Network multicenter study. J Am Coll Cardiol 52 (2008) 85-98
30. Leyk D., Essfeld D., Hoffmann U., Wunderlich H.G., Baum K., and Stegemann J. Postural effect on cardiac output, oxygen uptake and lactate during cycle exercise of varying intensity. Eur J Appl Physiol Occup Physiol 68 (1994) 30-35