메뉴 건너뛰기




Volumn 72, Issue 3, 2010, Pages 373-377

BMP inhibition with dorsomorphin limits adipogenic potential of preadipocytes

Author keywords

Adipocyte differentiation; BMP; Dorsomorphin; Smad

Indexed keywords

(6 (4 (2 PIPERIDIN 1 YLETHOXY)PHENYL)) 3 PYRIDIN 4 YLPYRAZOLO(1,5 A)PYRIMIDINE; (6-(4-(2-PIPERIDIN-1-YLETHOXY)PHENYL))-3-PYRIDIN-4-YLPYRAZOLO(1,5-A)PYRIMIDINE; BONE MORPHOGENETIC PROTEIN; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE;

EID: 77950353628     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.09-0442     Document Type: Article
Times cited : (16)

References (24)
  • 1
    • 0027721063 scopus 로고
    • Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages
    • Ahrens, M., Ankenbauer, T., Schröder, D., Hollnagel, A., Mayer, H. and Gross, G. 1993. Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages. DNA Cell Biol. 12: 871-880.
    • (1993) Dna Cell Biol , vol.12 , pp. 871-880
    • Ahrens, M.1    Ankenbauer, T.2    Schröder, D.3    Hollnagel, A.4    Mayer, H.5    Gross, G.6
  • 2
    • 33748374453 scopus 로고    scopus 로고
    • Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: Role of the BMP-4 gene
    • Bowers, R.R., Kim, J.W., Otto, T.C. and Lane, M.D. 2006. Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: role of the BMP-4 gene. Proc. Natl. Acad. Sci. U.S.A. 103: 13022-13027.
    • (2006) Proc. Natl. Acad. Sci. U.s.a , vol.103 , pp. 13022-13027
    • Bowers, R.R.1    Kim, J.W.2    Otto, T.C.3    Lane, M.D.4
  • 3
    • 0036904895 scopus 로고    scopus 로고
    • Genetic analysis of the mammalian transforming growth factor-β superfamily
    • Chang, H., Brown, C.W. and Matzuk, M.M. 2002. Genetic analysis of the mammalian transforming growth factor-β superfamily. Endocr. Rev. 23: 787-823.
    • (2002) Endocr. Rev , vol.23 , pp. 787-823
    • Chang, H.1    Brown, C.W.2    Matzuk, M.M.3
  • 4
    • 0038322020 scopus 로고    scopus 로고
    • Transforming growth factor-β inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function
    • Choy, L. and Derynck, R. 2003. Transforming growth factor-β inhibits adipocyte differentiation by Smad3 interacting with CCAAT/enhancer-binding protein (C/EBP) and repressing C/EBP transactivation function. J. Biol. Chem. 278: 9609-9619.
    • (2003) J. Biol. Chem , vol.278 , pp. 9609-9619
    • Choy, L.1    Derynck, R.2
  • 5
    • 0031454239 scopus 로고    scopus 로고
    • Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-β1 transgenic mice
    • Clouthier, D.E., Comerford, S.A. and Hammer, R.E. 1997. Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-β1 transgenic mice. J. Clin. Invest. 100: 2697-2713.
    • (1997) J. Clin. Invest , vol.100 , pp. 2697-2713
    • Clouthier, D.E.1    Comerford, S.A.2    Hammer, R.E.3
  • 6
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGF β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
    • Dennler, S., Itoh, S., Vivien, D., ten Dijke, P., Huet, S. and Gauthier, J.M. 1998. Direct binding of Smad3 and Smad4 to critical TGF β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17: 3091-3100.
    • (1998) Embo J , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    ten Dijke, P.4    Huet, S.5    Gauthier, J.M.6
  • 7
    • 48649094068 scopus 로고    scopus 로고
    • A sensitive detection of phospho-Smad1/5/8 and Smad2 in Western blot analyses
    • Funaba, M. and Murakami, M. 2008. A sensitive detection of phospho-Smad1/5/8 and Smad2 in Western blot analyses. J. Biochem. Biophys. Methods 70: 816-819.
    • (2008) J. Biochem. Biophys. Methods , vol.70 , pp. 816-819
    • Funaba, M.1    Murakami, M.2
  • 8
    • 0034805751 scopus 로고    scopus 로고
    • The effects of AICAR on adipocyte differentiation of 3T3-L1 cells
    • Habinowski, S.A. and Witters, L.A. 2001. The effects of AICAR on adipocyte differentiation of 3T3-L1 cells. Biochem. Biophys. Res. Commun. 286: 852-856.
    • (2001) Biochem. Biophys. Res. Commun , vol.286 , pp. 852-856
    • Habinowski, S.A.1    Witters, L.A.2
  • 10
    • 33845972272 scopus 로고    scopus 로고
    • Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP
    • Hurley, R.L., Barré, L.K., Wood, S.D., Anderson, K.A., Kemp, B.E., Means, A.R. and Witters, L.A. 2006. Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP. J. Biol. Chem. 281: 36662-36672.
    • (2006) J. Biol. Chem , vol.281 , pp. 36662-36672
    • Hurley, R.L.1    Barré, L.K.2    Wood, S.D.3    Anderson, K.A.4    Kemp, B.E.5    Means, A.R.6    Witters, L.A.7
  • 11
    • 0342542810 scopus 로고
    • Type β transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts
    • Ignotz, R.A. and Massagué, J. 1985. Type β transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 82: 8530-8534.
    • (1985) Proc. Natl. Acad. Sci. U.s.a , vol.82 , pp. 8530-8534
    • Ignotz, R.A.1    Massagué, J.2
  • 12
    • 0037085441 scopus 로고    scopus 로고
    • Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
    • Korchynskyi, O. and ten Dijke, P. 2002. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J. Biol. Chem. 277: 4883-4891.
    • (2002) J. Biol. Chem , vol.277 , pp. 4883-4891
    • Korchynskyi, O.1    ten Dijke, P.2
  • 13
    • 0018850985 scopus 로고
    • A simple, rapid, and sensitive DNA assay procedure
    • Labarca, C. and Paigen, K. 1980. A simple, rapid, and sensitive DNA assay procedure. Anal. Biochem. 102: 344-352.
    • (1980) Anal. Biochem , vol.102 , pp. 344-352
    • Labarca, C.1    Paigen, K.2
  • 14
    • 0033616128 scopus 로고    scopus 로고
    • Role of the CCAAT enhancer binding proteins (C/EBPs) in adipocyte differentiation
    • Lane, M.D., Tang, Q.Q. and Jiang, M.S. 1999. Role of the CCAAT enhancer binding proteins (C/EBPs) in adipocyte differentiation. Biochem. Biophys. Res. Commun. 266: 677-683.
    • (1999) Biochem. Biophys. Res. Commun , vol.266 , pp. 677-683
    • Lane, M.D.1    Tang, Q.Q.2    Jiang, M.S.3
  • 15
    • 21344455768 scopus 로고    scopus 로고
    • BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling cross-talk
    • Miyazono, K., Maeda, S. and Imamura, T. 2005. BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine Growth Factor Rev. 16: 251-263.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 251-263
    • Miyazono, K.1    Maeda, S.2    Imamura, T.3
  • 16
    • 63349097519 scopus 로고    scopus 로고
    • Receptor expression modulates the specificity of transforming growth factor-β signaling pathways
    • Murakami, M., Kawachi, H., Ogawa, K., Nishino, Y. and Funaba, M. 2009. Receptor expression modulates the specificity of transforming growth factor-β signaling pathways. Genes Cells 14: 469-482.
    • (2009) Genes Cells , vol.14 , pp. 469-482
    • Murakami, M.1    Kawachi, H.2    Ogawa, K.3    Nishino, Y.4    Funaba, M.5
  • 17
    • 0026793195 scopus 로고
    • Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O
    • Ramírez-Zacarías, J.L., Castro-Muñozledo, F. and Kuri-Harcuch, W. 1992. Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O. Histochemistry 97: 493-497.
    • (1992) Histochemistry , vol.97 , pp. 493-497
    • Ramírez-Zacarías, J.L.1    Castro-Muñozledo, F.2    Kuri-Harcuch, W.3
  • 18
    • 33845864967 scopus 로고    scopus 로고
    • Adipocytes as regulators of energy balance and glucose homeostasis
    • Rosen, E.D. and Spiegelman, B.M. 2006. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 444: 847-853.
    • (2006) Nature , vol.444 , pp. 847-853
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 19
    • 0037078328 scopus 로고    scopus 로고
    • Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes
    • Skillington, J., Choy, L. and Derynck, R. 2002. Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes. J. Cell Biol. 159: 135-146.
    • (2002) J. Cell Biol , vol.159 , pp. 135-146
    • Skillington, J.1    Choy, L.2    Derynck, R.3
  • 20
    • 3042759742 scopus 로고    scopus 로고
    • Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage
    • Tang, Q.Q., Otto, T.C. and Lane, M.D. 2004. Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage. Proc. Natl. Acad. Sci. U.S.A. 101: 9607-9611.
    • (2004) Proc. Natl. Acad. Sci. U.s.a , vol.101 , pp. 9607-9611
    • Tang, Q.Q.1    Otto, T.C.2    Lane, M.D.3
  • 21
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARg
    • Tontonoz, P. and Spiegelman, B.M. 2008. Fat and beyond: the diverse biology of PPARg. Annu. Rev. Biochem. 77: 289-312.
    • (2008) Annu. Rev. Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 22
    • 33847014029 scopus 로고    scopus 로고
    • Adipocyte biology
    • Trayhurn, P. 2007. Adipocyte biology. Obes. Rev. 8: 41-44.
    • (2007) Obes. Rev , vol.8 , pp. 41-44
    • Trayhurn, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.