Clinical features associated with poor pharmacologic adherence in bipolar disorder: Results from the STEP-BD study

Journal of Clinical Psychiatry

Volumn 71, Issue 3, 2010, Pages 296-303

  Perlis, Roy H ^a   Ostacher, Michael J ^a   Miklowitz, David J ^b   Hay, Aleena ^a   Nierenberg, Andrew A ^a   Thase, Michael E ^c   Sachs, Gary S ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PSYCHOTROPIC AGENT;

ALCOHOLISM; ANXIETY DISORDER; APPETITE; ARTICLE; BIPOLAR DISORDER; CLINICAL FEATURE; COHORT ANALYSIS; CONSTIPATION; DEMOGRAPHY; DEPRESSION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; EXTRAPYRAMIDAL SYMPTOM; FEMALE; FOLLOW UP; HUMAN; IRRITABILITY; MAJOR CLINICAL STUDY; MALE; MANIA; MEMORY DISORDER; MONTGOMERY ASBERG DEPRESSION RATING SCALE; ONSET AGE; PATIENT COMPLIANCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PSYCHOEDUCATION; QUALITY OF LIFE; RAPID CYCLING BIPOLAR DISORDER; SEDATION; SEXUAL DYSFUNCTION; SIDE EFFECT; SUICIDE ATTEMPT; TREMOR; XEROSTOMIA; YOUNG MANIA RATING SCALE;

ADOLESCENT; ADULT; AGE OF ONSET; ALCOHOLISM; ANTIMANIC AGENTS; BIPOLAR DISORDER; COMORBIDITY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; HUMANS; LOGISTIC MODELS; LONGITUDINAL STUDIES; MALE; MEDICATION ADHERENCE; PROSPECTIVE STUDIES; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTROPIC DRUGS; QUESTIONNAIRES; RISK FACTORS; SELF CONCEPT; SEVERITY OF ILLNESS INDEX; SUICIDE, ATTEMPTED; TREATMENT OUTCOME;

EID: 77950310149     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.09m05514yel     Document Type: Article

References (47)

1. Hirschfeld RA, Bowden CL, Gitlin MJ, et al. Practice Guideline for the Treatment of Patients With Bipolar Disorder (revision). Am J Psychiatry 2002;159(suppl 4).
2. Keck PE, Perlis RH, Otto MW, et al. Expert Consensus Guideline Series: Treatment of Bipolar Disorder 2004. Postgrad Med 2004.
3. Suppes T, Dennehy EB, Hirschfeld RM, et al, and the Texas Consensus Conference Panel on Medication Treatment of Bipolar Disorder. The Texas implementation of medication algorithms: update to the algorithms for treatment of bipolar I disorder. J Clin Psychiatry. 2005;66(7):870-886.
4. Keck PE Jr, McElroy SL, Strakowski SM, et al. Compliance with maintenance treatment in bipolar disorder. Psychopharmacol Bull. 1997;33(1):87-91.
5. Sajatovic M, Valenstein M, Blow FC, et al. Treatment adherence with antipsychotic medications in bipolar disorder. Bipolar Disord. 2006;8(3):232-241.
6. Sajatovic M, Valenstein M, Blow F, et al. Treatment adherence with lithium and anticonvulsant medications among patients with bipolar disorder. Psychiatr Serv. 2007;58(6):855-863.
7. Colom F, Vieta E, Martínez-Arán A, et al. Clinical factors associated with treatment noncompliance in euthymic bipolar patients. J Clin Psychiatry. 2000;61(8):549-555.
8. Gianfrancesco FD, Sajatovic M, Rajagopalan K, et al. Antipsychotic treatment adherence and associated mental health care use among individuals with bipolar disorder. Clin Ther. 2008;30(7):1358-1374.
9. Lew KH, Chang EY, Rajagopalan K, et al. The effect of medication adherence on health care utilization in bipolar disorder. Manag Care Interface. 2006;19(9):41-46.
10. Müller-Oerlinghausen B, Müser-Causemann B, Volk J. Suicides and parasuicides in a high-risk patient group on and off lithium long-term medication. J Affect Disord. 1992;25(4):261-269.
11. Gonzalez-Pinto A, Mosquera F, Alonso M, et al. Suicidal risk in bipolar I disorder patients and adherence to long-term lithium treatment. Bipolar Disord. 2006;8(5 Pt 2):618-624.
12. Perlis RH, Ostacher MJ, Patel JK, et al. Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). Am J Psychiatry. 2006;163(2):217-224.
13. Sajatovic M, Davies M, Hrouda DR. Enhancement of treatment adherence among patients with bipolar disorder. Psychiatr Serv. 2004;55(3):264-269.
14. Sajatovic M, Biswas K, Kilbourne AK, et al. Factors associated with prospective long-term treatment adherence among individuals with bipolar disorder. Psychiatr Serv. 2008;59(7):753-759.
15. Baldessarini RJ, Perry R, Pike J. Factors associated with treatment nonadherence among US bipolar disorder patients. Hum Psychopharmacol. 2008;23(2):95-105.
16. Manwani SG, Szilagyi KA, Zablotsky B, et al. Adherence to pharmacotherapy in bipolar disorder patients with and without co-occurring substance use disorders. J Clin Psychiatry. 2007;68(8):1172-1176.
17. Aagaard J, Vestergaard P, Maarbjerg K. Adherence to lithium prophylaxis, II: multivariate analysis of clinical, social, and psychosocial predictors of nonadherence. Pharmacopsychiatry. 1988;21(4):166-170.
18. Johnson FR, Ozdemir S, Manjunath R, et al. Factors that affect adherence to bipolar disorder treatments: a stated-preference approach. Med Care. 2007;45(6):545-552.
19. Sajatovic M, Elhaj O, Youngstrom EA, et al. Treatment adherence in individuals with rapid cycling bipolar disorder: results from a clinical-trial setting. J Clin Psychopharmacol. 2007;27(4):412-414.
20. Sachs GS, Thase ME, Otto MW, et al. Rationale, design, and methods of the systematic treatment enhancement program for bipolar disorder (STEP-BD). Biol Psychiatry. 2003;53(11):1028-1042.
21. Sheehan DV, Lecrubier Y, Sheehan KH, et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59(suppl 20):22-33, quiz 34-57.
22. Sachs GS, Guille C, McMurrich SL. A clinical monitoring form for mood disorders. Bipolar Disord. 2002;4(5):323-327.
23. Costa PTJ, McCrae RR. Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI) Professional Manual. Odessa, FL: Psychological Assessment Resources Inc; 1992.
24. Dennehy EB, Bauer MS, Perlis RH, et al. Concordance with treatment guidelines for bipolar disorder: data from the systematic treatment enhancement program for bipolar disorder. Psychopharmacol Bull. 2007;40(3):72-84.
25. Miklowitz DJ, Otto MW. Psychosocial interventions for bipolar disorder: a review of literature and introduction of the systematic treatment enhancement program. Psychopharmacol Bull. 2007;40(4):116-131.
26. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry. 1979;134(4):382-389.
27. Young RC, Biggs JT, Ziegler VE, et al. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry. 1978;133(5):429-435.
28. Endicott J, Nee J, Harrison W, et al. Quality of Life Enjoyment and Satisfaction Questionnaire: a new measure. Psychopharmacol Bull. 1993;29(2):321-326.
29. Leon AC, Solomon DA, Mueller TI, et al. The Range of Impaired Functioning Tool (LIFE-RIFT): a brief measure of functional impairment. Psychol Med. 1999;29(4):869-878.
30. Otto MW, Simon NM, Wisniewski SR, et al, and the STEP-BD Investigators. Prospective 12-month course of bipolar disorder in out-patients with and without comorbid anxiety disorders. Br J Psychiatry. 2006;189(1):20-25.
31. Warden D, Rush AJ, Wisniewski SR, et al. What predicts attrition in second step medication treatments for depression? a STAR*D report. Int J Neuropsychopharmacol. 2009;12(4):459-473.
32. Arts B, Jabben N, Krabbendam L, et al. Meta-analyses of cognitive functioning in euthymic bipolar patients and their first-degree relatives. Psychol Med. 2008;38(6):771-785.
33. Ridker PM, Buring JE, Rifai N, et al. Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score. JAMA. 2007;297(6):611-619.
34. Rudolph JL, Jones RN, Levkoff SE, et al. Derivation and validation of a preoperative prediction rule for delirium after cardiac surgery. Circulation. 2009;119(2):229-236.
35. Cook NR. Use and misuse of the receiver operating characteristic curve in risk prediction. Circulation. 2007;115(7):928-935.
36. Cook NR. Statistical evaluation of prognostic versus diagnostic models: beyond the ROC curve. Clin Chem. 2008;54(1):17-23.
37. Safren SA, Hendriksen ES, Desousa N, et al. Use of an on-line pager system to increase adherence to antiretroviral medications. AIDS Care. 2003;15(6):787-793.
38. Safren SA, Otto MW, Worth JL, et al. Two strategies to increase adherence to HIV antiretroviral medication: life-steps and medication monitoring. Behav Res Ther. 2001;39(10):1151-1162.
39. Kim HS, Oh JA. Adherence to diabetes control recommendations: impact of nurse telephone calls. J Adv Nurs. 2003;44(3):256-261.
40. Depp CA, Moore DJ, Patterson TL, et al. Psychosocial interventions and medication adherence in bipolar disorder. Dialogues Clin Neurosci. 2008;10(2):239-250.
41. Colom F, Lam D. Psychoeducation: improving outcomes in bipolar disorder. Eur Psychiatry. 2005;20(5-6):359-364. (Pubitemid 41318000)
42. Berg KM, Arnsten JH. Practical and conceptual challenges in measuring antiretroviral adherence. J Acquir Immune Defic Syndr. 2006;43 (suppl 1):S79-S87.
43. Zeber JE, Copeland LA, Good CB, et al. Therapeutic alliance perceptions and medication adherence in patients with bipolar disorder. J Affect Disord. 2008;107(1-3):53-62.
44. Copeland LA, Zeber JE, Salloum IM, et al. Treatment adherence and illness insight in veterans with bipolar disorder. J Nerv Ment Dis. 2008;196(1):16-21.
45. Clatworthy J, Bowskill R, Rank T, et al. Adherence to medication in bipolar disorder: a qualitative study exploring the role of patients' beliefs about the condition and its treatment. Bipolar Disord. 2007;9(6):656-664.
46. Rosa AR, Marco M, Fachel JM, et al. Correlation between drug treatment adherence and lithium treatment attitudes and knowledge by bipolar patients. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31(1):217-224.
47. Adams J, Scott J. Predicting medication adherence in severe mental disorders. Acta Psychiatr Scand. 2000;101(2):119-124.