Evaluation of the anti-endotoxin effects of polymyxin B in a feline model of endotoxemia

Journal of Feline Medicine and Surgery

Volumn 12, Issue 4, 2010, Pages 278-285

  Sharp, Claire R ^a   DeClue, Amy E ^a   Haak, Carol E ^a   Honaker, Allison R ^a   Reinero, Carol R ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; POLYMYXIN B; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; CAT; CAT DISEASE; ENDOTOXEMIA; GERMFREE ANIMAL; MALE; METABOLISM; RANDOMIZATION; TREATMENT OUTCOME;

ANIMALS; ANTI-BACTERIAL AGENTS; CAT DISEASES; CATS; ENDOTOXEMIA; MALE; POLYMYXIN B; RANDOM ALLOCATION; SPECIFIC PATHOGEN-FREE ORGANISMS; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA;

FELIDAE; NEGIBACTERIA;

EID: 77950297654     PISSN: 1098612X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfms.2009.12.014     Document Type: Article

References (43)

1. Brady C.A., Otto C.M., Van Winkle T.J., and King L.G. Severe sepsis in cats: 29 cases (1986-1998). J Am Vet Med Assoc 217 (2000) 531-535
2. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20 (1992) 864-874
3. Costello M.F., Drobatz K.J., Aronson L.R., and King L.G. Underlying cause, pathophysiologic abnormalities, and response to treatment in cats with septic peritonitis: 51 cases (1990-2001). J Am Vet Med Assoc 225 (2004) 897-902
4. Dow S.W., Curtis C.R., Jones R.L., and Wingfield W.E. Bacterial culture of blood from critically ill dogs and cats: 100 cases (1985-1987). J Am Vet Med Assoc 195 (1989) 113-117
5. Sergeeff J.S., Armstrong P.J., and Bunch S.E. Hepatic abscesses in cats: 14 cases (1985-2002). J Vet Intern Med 18 (2004) 295-300
6. Walker A.L., Jang S.S., and Hirsh D.C. Bacteria associated with pyothorax of dogs and cats: 98 cases (1989-1998). J Am Vet Med Assoc 216 (2000) 359-363
7. Greiner M., Wolf G., and Hartmann K. Bacteraemia in 66 cats and antimicrobial susceptibility of the isolates (1995-2004). J Feline Med Surg 9 (2007) 404-410
8. Hodgson J.C. Endotoxin and mammalian host responses during experimental disease. J Comp Pathol 135 (2006) 157-175
9. Munford R.S. Detoxifying endotoxin: time, place and person. J Endotoxin Res 11 (2005) 69-84
10. Rustici A., Velucchi M., Faggioni R., et al. Molecular mapping and detoxification of the lipid A binding site by synthetic peptides. Science 259 (1993) 361-365
11. Hermsen E.D., Sullivan C.J., and Rotschafer J.C. Polymyxins: pharmacology, pharmacokinetics, pharmacodynamics, and clinical applications. Infect Dis Clin North Am 17 (2003) 545-562
12. Tsuzuki H., Tani T., Ueyama H., and Kodama M. Lipopolysaccharide: neutralization by polymyxin B shuts down the signaling pathway of nuclear factor kappaB in peripheral blood mononuclear cells, even during activation. J Surg Res 100 (2001) 127-134
13. Brown M.A., and Jones W.K. NF-kappa B action in sepsis: the innate immune system and the heart. Front Biosci 9 (2004) 1201-1217
14. Liu S.F., and Malik A.B. NF-kappa B activation as a pathological mechanism of septic shock and inflammation. Am J Physiol Lung Cell Mol Physiol 290 (2006) L622-L645
15. Corrigan Jr. J.J., and Kiernat J.F. Effect of polymyxin B sulfate on endotoxin activity in a Gram-negative septicemia model. Pediatr Res 13 (1979) 48-51
16. Flynn P.M., Shenep J.L., Stokes D.C., et al. Polymyxin B moderates acidosis and hypotension in established, experimental Gram-negative septicemia. J Infect Dis 156 (1987) 706-712
17. Mayumi T., Takezawa J., Takahashi H., et al. Low-dose intramuscular polymyxin B improves survival of septic rats. Shock 11 (1999) 82-86
18. From A.H., Fong J.S., and Good R.A. Polymyxin B sulfate modification of bacterial endotoxin: effects on the development of endotoxin shock in dogs. Infect Immun 23 (1979) 660-664
19. Barton M.H., Parviainen A., and Norton N. Polymyxin B protects horses against induced endotoxaemia in vivo. Equine Vet J 36 (2004) 397-401
20. Morresey P.R., and Mackay R.J. Endotoxin-neutralizing activity of polymyxin B in blood after IV administration in horses. Am J Vet Res 67 (2006) 642-647
21. Parviainen A.K., Barton M.H., and Norton N.N. Evaluation of polymyxin B in an ex vivo model of endotoxemia in horses. Am J Vet Res 62 (2001) 72-76
22. Endo S., Inada K., Kikuchi M., et al. Clinical effects of intramuscular administration of a small dose of polymyxin B to patients with endotoxemia. Res Commun Chem Pathol Pharmacol 83 (1994) 223-235
23. Senturk S. Evaluation of the anti-endotoxic effects of polymyxin-E (colistin) in dogs with naturally occurred endotoxic shock. J Vet Pharmacol Ther 28 (2005) 57-63
24. Hughes B., Madan B.R., and Parratt J.R. Polymyxin B sulphate protects cats against the haemodynamic and metabolic effects of E coli endotoxin. Br J Pharmacol 74 (1981) 701-707
25. DeClue A.E., Williams K.J., Sharp C., et al. Systemic response to low dose endotoxin infusion in cats. Vet Immunol Immunopath 132 2-4 (2009) 167-174
26. Stich A., and DeClue A.E. Pathogen associated molecular pattern-induced TNF, IL-1β, IL-6 and CXCL-8 production from feline whole blood culture. J Vet Emergency Crit Care 19 (2009) A1-10
27. Damsgaard C.T., Lauritzen L., Calder P.C., et al. Whole-blood culture is a valid low-cost method to measure monocytic cytokines - a comparison of cytokine production in cultures of human whole-blood, mononuclear cells and monocytes. J Immunol Methods 340 (2009) 95-101
28. Gosain A., and Gamelli R.L. A primer in cytokines. J Burn Care Rehabil 26 (2005) 7-12
29. Tracey K.J., Lowry S.F., Fahey III T.J., et al. Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog. Surg Gynecol Obstet 164 (1987) 415-422
30. Kreil E.A., Greene E., Fitzgibbon C., et al. Effects of recombinant human tumor necrosis factor alpha, lymphotoxin, and Escherichia coli lipopolysaccharide on hemodynamics, lung microvascular permeability, and eicosanoid synthesis in anesthetized sheep. Circ Res 65 (1989) 502-514
31. Casey L.C., Balk R.A., and Bone R.C. Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med 119 (1993) 771-778
32. Marano M.A., Fong Y., Moldawer L.L., et al. Serum cachectin/tumor necrosis factor in critically ill patients with burns correlates with infection and mortality. Surg Gynecol Obstet 170 (1990) 32-38
33. Otto C.M., and Rawlings C.A. Tumor necrosis factor production in cats in response to lipopolysaccharide: an in vivo and in vitro study. Vet Immunol Immunopathol 49 (1995) 183-188
34. Jaber B.L., Sundaram S., Cendoroglo Neto M., et al. Polymyxin-B stimulates tumor necrosis factor-alpha production by human peripheral blood mononuclear cells. Int J Artif Organs 21 (1998) 269-273
35. Groom A.C., and Rowlands S. The cardiac output and blood volume of the anaesthetized cat. Phys Med Biol 3 (1958) 138-156
36. Deitch E. Animal models of sepsis and shock: a review and lessons learned. Shock 9 (1998) 1-11
37. Laupland K.B. Fever in the critically ill medical patient. Crit Care Med 37 suppl (2009) S273-S278
38. Su F., Nguyen N.D., Wang Z., et al. Fever control in septic shock: beneficial or harmful?. Shock 23 (2005) 516-520
39. Viswanath D.V., and Jenkins H.J. Neuromuscular block of the polymyxin group of antibiotics. J Pharm Sci 67 (1978) 1275-1280
40. Sanders Jr. W.E., and Sanders C.C. Toxicity of antibacterial agents: mechanism of action on mammalian cells. Annu Rev Pharmacol Toxicol 19 (1979) 53-83
41. Kunin C.M. Nephrotoxicity of antibiotics. J Am Med Assoc 202 (1967) 204-208
42. Kunin C.M., and Bugg A. Binding of polymyxin antibiotics to tissues: the major determinant of distribution and persistence in the body. J Infect Dis 124 (1971) 394-400
43. Otto C., Drobatz K., and Soter C. Endotoxemia and tumor necrosis factor activity in dogs with naturally occurring parvoviral enteritis. J Vet Int Med 11 (1997) 65-70