Widespread pulmonary granulomatosis following long time intravenous drug abuse-A case report

Forensic Science International

Volumn 197, Issue 1-3, 2010, Pages

  Dettmeyer, R B ^a   Verhoff, M A ^a   Bruckel B ^a   Walter, D ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Energy dispersive X ray (EDX); Foreign particle embolization; I.v. drug abuse; Pulmonary granulomatosis

Indexed keywords

7 AMINOFLUNITRAZEPAM; CELLULOSE; METHADONE;

ADULT; ARTICLE; AUTOPSY; CASE REPORT; CHRONIC HEPATITIS; COTTON; CRYSTAL; DISEASE SEVERITY; DRUG DEPENDENCE TREATMENT; ELECTRON DIFFRACTION; ELECTRON MICROSCOPY; FATALITY; FOREIGN BODY GRANULOMA; HEART HYPERTROPHY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTRAVENOUS DRUG ABUSE; LONG TERM EXPOSURE; LUNG DISEASE; LUNG GRANULOMATOSIS; LUNG NODULE; MALE; MYOCARDITIS; PARTICLE SIZE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SUDDEN DEATH;

EID: 77950296444     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2009.12.066     Document Type: Article

References (22)

1. Dettmeyer R., Schmidt P., Dreisvogt C., Madea B. Pulmonary edema in fatal heroin overdose: immunohistological investigation with IgE, collagen IV and laminin - no increase of defects of alveolar-capillary membranes. Forensic Sci. Int. 2000, 110(2):87-96.
2. Kringsholm B., Christoffersen P. Lung and heart pathology in fatal drug addiction. A consecutive autopsy study. Forensic Sci. Int. 1987, 34:39-51.
3. Kringsholm B., Christoffersen P. The nature and the occurrence of birefringent material in different organs in fatal drug addiction. Forensic Sci. Int. 1987, 34:53-62.
4. Karch S.B. Karch's pathology of drug abuse 2009, CRC Press, Boca Raton, London, New York, 523-533. 4th ed.
5. Brinkmann B., Kollmeier J., Müller K.M. Fremdkörper-Endangiitis bei Fixerpneumopathie. Atemwegs- und Lungenkrankheiten 1991, 17:282-283.
6. Müller K.M. Fixerpneumopathie. Pneumologie 2004, 58:552.
7. Hopkins G.B. Pulmonary angiothrombotic granulomas in drug offenders. JAMA 1972, 221(8):909-911.
8. Pare J.P., Cote G., Fraser R.S. Long-term follow-up of drug abusers with intravenous talcosis. Am. Rev. Resp. Dis. 1984, 139(1):233-241.
9. Raijs J., Harm T., Ormstad K. Postmortem findings of pulmonary lesions of older datum in intravenous drug addicts. A forensic-pathologic study. Virchows Arch. A Pathol. Anat. Histopathol. 1984, 402(4):405-414.
10. Angelos M.G., Sheets C.A., Zych P.R. Needle emboli to lung following intravenous drug abuse. J. Emerg. Med. 1986, 4(5):391-396.
11. Lewis T.D., Henry D.A. Needle embolus: a unique complication of intravenous drug abuse. Ann. Emerg. Med. 1985, 14(9):906-908.
12. Thorne L.B., Collins K.A. Speedballing with needle embolization: case study and review of the literature. J. Forensic Sci. 1998, 43(5):1074-1076.
13. Püschel K. Fremdkörpergranulome nach i.v. Drogenapplikation. Ber. Path. 1986, 102:400-401.
14. Püschel K., Schoof W. Zur Morphogenese hämatogen entstandener Fremdkörpergranulome im Lungenparenchym. Beitr. Gerichtl. Med. 1987, 45:121-128.
15. Ed Crouch M.D., Andrew Churg M.D. Progressive massive fibrosis of the lung secondary to intravenous injection of talc. A pathologic and mineralogic analysis. Am. J. Clin. Pathol. 1983, 80(October (4)):520-526.
16. Groth D.H., McKay G.R., Crable J.V., Cochran T.H. Intravenous injection of talc in a narcotic addict. Arch. Pathol. 1972, 94(2):171-178.
17. Püschel K. Pulmonales Mikroemboliesyndrom durch Injektion einer Tablettensuspension. Gerichtsmedizin. Festschrift für Wilhelm Holczabek 1988, 163-166. Franz Deuticke, Wien. G. Bauer (Ed.).
18. Gross E.M. Talc embolism: sudden death following intravenous injection of phenyltoloxamine. Forensic Sci. Int. 1973, 2:475-480.
19. Zientara M., Moore S. Fatal talc embolism in a drug addict. Hum. Pathol. 1970, 1:324-327.
20. H.-J. Woitowitz, K. Rödelsperger, J. Manke, B. Brückel, Identification and quantification of asbestos and other mineral fibres in human lung tissue with analytical scanning transmission electron microscopy (STEM), Schriftenreihe der Bundesanstalt für Arbeitsschutz, 1988 - Sonderschrift - S 27.
21. Thomashefski J.F., Hirsch C.S. The pulmonary vascular lesions of intravenous drug abuse. Hum. Pathol. 1980, 11(2):133-145.
22. Dettmeyer R., Preuß J., Wollersen H., Madea B. Heroin-associated nephropathy. Exp. Opin. Drug Saf. 2005, 4:19-28.