Hepatocyte growth factor ameliorates progression of interstitial injuries in tubular epithelial cells

Scandinavian Journal of Urology and Nephrology

Volumn 44, Issue 2, 2010, Pages 121-128

  Mou, Shan ^a   Wang, Qin ^a   Shi, Beili ^a   Gu, Leyi ^a   Ni, Zhaohui ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Diabetic nephropathy; Hepatocyte growth factor; Tubulointerstitial injury.

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; COLLAGEN TYPE 4; GLUCOSE; PLASMINOGEN ACTIVATOR INHIBITOR 1; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

APOPTOSIS; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; HUMAN; HUMAN TISSUE; KIDNEY TUBULE CELL; NICK END LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

CELLS, CULTURED; CHRONIC DISEASE; DISEASE PROGRESSION; EPITHELIAL CELLS; HEPATOCYTE GROWTH FACTOR; HUMANS; KIDNEY DISEASES; KIDNEY TUBULES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77950295257     PISSN: 00365599     EISSN: 16512065     Source Type: Journal    
DOI: 10.3109/00365590903449340     Document Type: Article

References (17)

1. Renal Data System: USRDS 1998 Annual Data Report (NIH Publ No 98-3176). Washington, DC: US Government Printing Office; 1998.
2. Isermann B, Vinnikov IA, Madhusudhan T, Herzog S, Kashif M, Blautzik J, et al. Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis. Nat Med 2007;13:1349-1358
3. Beyenbach KW. Kidneys sans glomeruli. Am J Physiol Renal Physiol 2004;286:F811-27.
4. Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A, et al. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989;342:440-443
5. Matsumoto K, Nakamura T. Hepatocyte growth factor: renotropic role and potential therapeutics for renal diseases. Kidney Int 2001;59:2023-2038
6. Detrisac CJ, Sens MA, Garvin AJ, Spicer SS, Sens DA. Tissue culture of human kidney epithelial cells of proximal tubule origin. Kidney Int 1984;25:383-390
7. Akmal M. Hemodialysis in diabetic patients. Am J Kidney Dis 2001;38:S195-9.
8. Yamamoto T, Nakamura T, Noble NA, Ruoslahti E, Border WA. Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy. Proc Natl Acad Sci USA 1993;90:1814-1818
9. Taylor GA, Jeffers M, Webb CP, Koo HM, Anve M, Sekiguchi K, Vande-Woude GF. Decreased fibronectin expression in Met/HGF-mediated tumorigenesis. Oncogene 1998;17:1179-1183
10. Mizuno S, Nakamura TSuppressions of chronic glomerular injuries and TGF-b1 production by HGF in attenuation of murine diabetic nephropathy. Am J Physiol Renal Physiol 2004;286:F134-43.
11. Dworkin LD, Gong RJ, Tolbert E, Centracchio J, Yano N, Zanabli A, et al. Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury. Kidney Int 2004;65:409-419
12. Mizuno S, Matsumoto K, Kurosawa T, Mizuno- Horikawa Y, Nakamura T. Reciprocal balance of hepatocyte growth factor and transforming growth factor-beta 1 in renal fibrosis in mice. Kidney Int 2000;57:937-948
13. Schelling JR, Cleveland RP. Involvement of Fas-dependent apoptosis in renal tubular epithelial cell deletion in chronic renal failure. Kidney Int 1999;56:1313-1316
14. Fornoni, Li H, Foschi A, Striker GE, Striker LJ. Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporine A-induced apoptosis. Am J Pathol 2001;158:275-280
15. Liu Y, Sun AM, Dworkin LD. Hepatocyte growth factor protects renal epithelial cells from apoptotic cell death. Biochem Biophys Res Commun 1998;246:821-826
16. Ziyadeh FN. Significance of tubulointerstitial changes in diabetic renal disease. Kidney Int 1996;49(Suppl 54):S10-3.
17. Taniyama Y, Morishita R, Nakagami H, Moriguchi A, Sakonjo H, Shokei-Kim, et al. Potential contribution of a novel antifibrotic factor, hepatocyte growth factor, to prevention of myocardial fibrosis by angiotensin II blockade in cardiomyopathic hamsters. Circulation 2000;102:246-252