Open label trial of the tolerability and efficacy of zonisamide in the treatment of alcohol dependence

American Journal of Drug and Alcohol Abuse

Volumn 36, Issue 2, 2010, Pages 102-105

  Knapp, Clifford M ^a   Sarid Segal, Ofra ^a   Richardson, Mark A ^a   Colaneri, Laurie Sickles ^a   Afshar, Maryam ^a   Devine, Eric ^a   Streeter, Chris C ^a   Piechniczek Buczek, Joanne ^a   Ciraulo, Domenic A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcoholism; Anticonvulsant; Clinical trial; Neuropsychological tests

Indexed keywords

ZONISAMIDE;

ADULT; ALCOHOL CONSUMPTION; ALCOHOLIC BEVERAGE; ALCOHOLISM; ARTICLE; ATTENTION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; MALE; MOOD DISORDER; SADNESS; SEDATION; SEIZURE; SIDE EFFECT; TASK PERFORMANCE; TEARFULNESS; VERBAL BEHAVIOR; VISUOMOTOR COORDINATION;

ADULT; ALCOHOL-RELATED DISORDERS; ANALYSIS OF VARIANCE; ANTICONVULSANTS; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; INTENTION TO TREAT ANALYSIS; ISOXAZOLES; MALE; MIDDLE AGED; PATIENT SELECTION; PSYCHIATRIC STATUS RATING SCALES; QUESTIONNAIRES; TREATMENT OUTCOME;

EID: 77950275509     PISSN: 00952990     EISSN: 10979891     Source Type: Journal    
DOI: 10.3109/00952991003674812     Document Type: Article

References (23)

1. Johnson BA, Ait-Daoud N, Bowden Cl, DiClemente CC, Roache JD, Lawson K, Javors MA. Oral topiramate for treatment of alcohol dependence: A randomized controlled trial. Lancet 2003; 361:1677-1685.
2. JohnsonBA,Rosenthal N, Capece JA,Wiegand F, Mao L,BeyersK,McKay A, Ait-Daoud N, Anton RF, Ciraulo DA, Kranzler HR, Mann K, O'Malley SS, Swift RM. Topiramate for treating alcohol dependence: A randomized controlled trial. JAMA 2007; 298:1641-1651.
3. Maryanoff BE, Costanzo MJ, Nortey SO, Greco MN, Shank RP, Schupsky JJ, Ortegon MP, Vaught JL. Structure-activity studies on anticonvulsant sugar sulfamates related to topiramate. Enhanced potency with cyclic sulfate derivatives. J Med Chem 1998; 41:1315-1343.
4. Knapp CM, MercadoM, Markley TL, Crosby S, Ciraulo DA, Kornetsky C. Zonisamide decreases ethanol intake in rats and mice. Pharmacol Biochem Behav 2007; 87:65-72.
5. Sarid-Segal O, Knapp CM, Burch W, Richardson M, Bhatia S, DeQuatro K, Afshar M, Richambault C, Sickles L, Devine E, Ciraulo DA. The anticonvulsant zonisamide reduces ethanol self-administration by risky drinkers. American J Drug Alc Abuse 2009; 35:316-319.
6. Park SP, Hwang YH, Lee HW, Suh CK, Kwon SH, Lee BI. Long-term cognitive andmood effects of zonisamide monotherapy in epilepsy patients. Epilepsy Behav 2008; 2:102-108.
7. Fritz N, Glogau S, Hoffman J, Rademacher M, Elger CE, Helmstaedter C. Efficacy and cognitive side effects of tiagabine and topiramate in patients with epilepsy. Epilepsy Behav 2005; 6: 373-381.
8. Werz MA, Schoenberg MR, Meador KJ, Loring DW, Ray PG, Kaul-Gupta R, Ogrocki P. Subjective preference for lamotrigine or topiramate in healthy volunteers: Relationship to cognitive and behavioral functioning. Epilepsy Behavior 2006; 8:181-191.
9. Knapp CM, Sarid-Segal O, Richardson M, Afshar M, Piechniczek-Buczek J, Koplow J, Ciraulo DA. The effects of topiramate on alcohol use and cognitive function in alcohol dependence. Alc Clin Exp Res Supp 2006; 30:107A.
10. Benton Al, de Hamsher KS. Multilinguial aphasia examination. Iowa City, IA: 1989.
11. Smith A. Symbol Digits Modalities Test. Los Angeles:Western Psychological Services, 1982.
12. FirstMB, Spitzer RL, Gibbon M,Williams JBW. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition. (SCID-I/P) New York: Biometrics Research, New York State Psychiatric Institute, 2002.
13. Sobell LC, Sobell MB, Leo GI, Cancilla A. Reliability of a timeline method: Assessing normal drinkers' reports of recent drinking and a comparative evaluation across several populations. Br J Addict 1988; 83: 393-402.
14. Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M. Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption-ll. Addiction 1993; 88:791-804.
15. Seino M, Fujitani B. (Zonisamide) Clinical Efficacy and Use in Epilepsy. In Antiepileptic Drugs. Levy RH, Mattson RH, Meldrum, Perucca E, eds. Philadelphia, PA: Lippincott, Williams, and Wilkins, 2002; 885-891.
16. Starosta AN, Leeman RF, Volpicelli JR. The BRENDA model: Integrating psychosocial treatment and pharmacotherapy for the treatment of alcohol use disorders. J Psychiatr Pract 2006; 12:80-89.
17. Sullivan JT, Sykora K, Schneiderman J, Naranjo CA, Sellers EM. Assessment of alcohol withdrawal: The revised clinical institute withdrawal assessment for alcohol scale (CIWA-AR). Br JAddict 1989; 84:1353-1357.
18. Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967; 6:278-296.
19. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol 1959; 32:50-55.
20. Anton RF, Moak DH, Latham PK. The Obsessive Compulsive Drinking Scale: A new method of assessing outcome in alcoholism treatment studies. Arch Gen Psychiatry 1996; 53:225-231.
21. Selzer ML, Vinokur A, van Rooijen L. A self-administered short Michigan Alcoholism Screening Test (SMAST). J Studies Alc 1975; 36:11-126.
22. Skinner HA, Horn JL. Alcohol Dependence Scale: Users Guide. Toronto, Ontario: Toronto Addiction Research Foundation, 1984.
23. Arias A, Covault J, Feinn R, Kranzler H. Zonisamide for alcohol dependence: Preliminary analysis. Alc Clin Exp Res 2009; 33:116A.