Estrogen receptor β agonism increases survival in experimentally induced sepsis and ameliorates the genomic sepsis signature: A pharmacogenomic study

Journal of Infectious Diseases

Volumn 201, Issue 8, 2010, Pages 1250-1257

  Christaki, Eirini ^a   Opal, Steven M ^a   Keith Jr , James C ^b   Kessinian, Nubar ^a   Palardy, John E ^a   Parejo, Nicolas A ^a   Lavallie, Edward ^b   Racie, Lisa ^b   Mounts, William ^b   Malamas, Michael S ^b   Mewshaw, Richard E ^b   Harris, Heather A ^b   Vlasuk, George P ^b  

^a BROWN UNIVERSITY   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR BETA; HORMONE RECEPTOR STIMULATING AGENT; PRINABEREL; TRANSCRIPTOME; UNCLASSIFIED DRUG; WAY 202196;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL OVERGROWTH; CELL PROTECTION; CONTROLLED STUDY; EXPERIMENTAL MODEL; FEMALE; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PHARMACOGENOMICS; PRIORITY JOURNAL; SEPSIS; SMALL INTESTINE; STREPTOCOCCUS PNEUMONIA; SURVIVAL; TISSUE INJURY; TRANSCRIPTION REGULATION;

ANIMALS; DISEASE MODELS, ANIMAL; ESTROGEN RECEPTOR BETA; FEMALE; GENE EXPRESSION PROFILING; MALE; MICE; MICE, INBRED BALB C; NAPHTHOLS; OXAZOLES; PNEUMONIA, PNEUMOCOCCAL; SEPSIS; TRANSCRIPTION, GENETIC;

EID: 77950270958     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/651276     Document Type: Article

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