Expression of NF-κB in Schwann cells and its effect on motor neuron apoptosis in spinal cord following sciatic nerves injury in rats

Journal of Medical Colleges of PLA

Volumn 22, Issue 2, 2007, Pages 92-96

  Wang, Yong tang ^a   Lu, Xiu min ^b   Yu, Ying ^b   Yang, Yan hong ^b   Gao, Jie ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b CHONGQING UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Apoptosis; Motor neuron; Nuclear factor kappa B; Sciatic nerves injury; Spinal cord

Indexed keywords

EID: 77950257306     PISSN: 10001948     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1000-1948(07)60020-3     Document Type: Article

References (9)

1. Wang YT, Lu XM, Jiang JX, et al. Activation of NF-kB and its regulation on IL-6 expression during LPS-induced liver injury [J]. J Med Coll PLA 2005, 20(5):268.
2. Thanos D, Mancatis T NF-kappaB: a lesson in family value [J]. Cell 1995, 80(4):529.
3. Friedman WJ, Thakur S, Seidman L, et al. Regulation of nerve growth factor mRNA by interleukin-l in rat hippocampal astrocytes is mediated by NF-kB [J]. J Biol Chem 1996, 271(49):31115.
4. Middleton G, Hamanoue M, Enokido Y, et al. Cytokine-in-duced nuclear factor kappa B activation promotes the survival of developing neurons [J]. J Cell Biol 2000, 148(2):325.
5. Piccioli P, Porcile C, Stanzione S, et al. Inhibition of nuclear factor-kappaB activation induces apoptosis in cerebellar granule cells [J]. J Neursci Res 2001, 66(6):1064.
6. Ramirez SH, Sanchez JF, Dimitri CA, et al. Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism [J]. J Neurochem 2001, 78(4):874.
7. Hunot S, Brugg B, Ricard D, et al. Nuclear translocation of NF-kB is increased FLin dopaminergic neurons of patients with Parkinson diease [J]. Proc Natl Acad Sci USA 1997, 94:7531.
8. Pizzi M, Goffi F, Boroni F, et al. Opposing roles for NF-kappa B/Rel factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1 beta [J]. J Biol Chem 2002, 277(23):20717.
9. Burnett MG, Zager EL Pathophysiology of peripheral nerve injury: a brief review [J]. Neurosurg Focus 2004, 16:El.