The Surgical Management of Primary and Metastatic Merkel Cell Carcinoma

Current Problems in Cancer

Volumn 34, Issue 1, 2010, Pages 77-96

  Gonzalez, Ricardo J ^a   Padhya, Tapan A ^b   Cherpelis, Basil S ^b,c   Prince, Melanie D ^b   Aya ay, Melanie L ^a   Sondak, Vernon K ^a   Cruse, C Wayne ^a,b   Zager, Jonathan S ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER SURGERY; CHEMOSURGERY; DISTANT METASTASIS; HEAD AND NECK CARCINOMA; HUMAN; MERKEL CELL TUMOR; METASTASIS; SENTINEL LYMPH NODE BIOPSY;

CARCINOMA, MERKEL CELL; HUMANS; SKIN NEOPLASMS;

EID: 77950254704     PISSN: 01470272     EISSN: 15356345     Source Type: Journal    
DOI: 10.1016/j.currproblcancer.2010.02.003     Document Type: Article

References (55)

1. Akhtar S., Oza K.K., and Wright J. Merkel cell carcinoma: report of 10 cases and review of the literature. J Am Acad Dermatol 43 5 Pt 1 (2000) 755-767
2. Medina-Franco H., Urist M.M., Fiveash J., et al. Multimodality treatment of Merkel cell carcinoma: case series and literature review of 1024 cases. Ann Surg Oncol 8 3 (2001) 204-208
3. Agelli M., and Clegg L.X. Epidemiology of primary Merkel cell carcinoma in the United States. J Am Acad Dermatol 49 5 (2003) 832-841
4. Hodgson N.C. Merkel cell carcinoma: changing incidence trends. J Surg Oncol 89 1 (2008) 1-4
5. Tai P. Merkel cell cancer: update on biology and treatment. Curr Opin Oncol 20 2 (2008) 196-200
6. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology, vol 1 (2008)
7. Bichakjian C.K., Lowe L., Loa C.D., et al. Merkel cell carcinoma: critical review with guidelines for multidisciplinary management. Cancer 110 1 (2007) 1-12
8. Allen P.J., Bowne W.B., Jacques D.P., et al. Merkel cell carcinoma: prognosis and treatment of patients from a single institution. J Clin Oncol 23 10 (2005) 2300-2309
9. Allen P.J., Zhang Z.F., and Coit D.G. Surgical management of Merkel cell carcinoma. Ann Surg 229 1 (1999) 97-105
10. Eng T.Y., Boersma M.G., Fuller C.D., et al. A comprehensive review of the treatment of Merkel cell carcinoma. Am J Clin Oncol 30 6 (2007) 624-636
11. Gillenwater A.M., Hessel A.C., Morrison W.H., et al. Merkel cell carcinoma of the head and neck: effect of surgical excision and radiation on recurrence and survival. Arch Otolaryngol Head Neck Surg 127 2 (2001) 149-154
12. Eng T.Y., Naguib M., Fuller C.D., et al. Treatment of recurrent Merkel cell carcinoma: an analysis of 46 cases. Am J Clin Oncol 27 6 (2004) 576-583
13. Stokes J.B., Graw K.S., Dengel L.T., et al. Patients with Merkel cell carcinoma tumors ≤1.0 cm in diameter are unlikely to harbor regional lymph node metastasis. J Clin Oncol 27 23 (2009) 3772-3777
14. Bajetta E., Celio L., Platania M., et al. Single institution series of early stage Merkel cell carcinoma: long term outcomes in 95 patients managed with surgery alone. Ann Surg Oncol 16 11 (2009) 2985-2993
15. Jabbour J., Cumming R., Scolyer R.A., et al. Merkel cell carcinoma: assessing the effect of wide local excision, lymph node dissection, and radiotherapy on recurrence and survival in early-stage disease-results from a review of 82 consecutive cases diagnosed between 1992 and 2004. Ann Surg Oncol 14 6 (2007) 1943-1952
16. Goepfert H., Remmler D., Silva E., et al. Merkel cell carcinoma (endocrine carcinoma of the skin) of the head and neck. Arch Otolaryngol 110 11 (1984) 707-712
17. Bielamowicz S., Smith D., and Abemayor E. Merkel cell carcinoma: an aggressive skin neoplasm. Laryngoscope 104 5 Pt 1 (1994) 528-532
18. Azizi L., Marsot-Dupuch K., Bigel P., et al. Merkel cell carcinoma: a rare cause of hypervascular nasal tumor. AJNR Am J Neuroradiol 22 7 (2001) 1389-1393
19. Brissett A.E., Olsen K.D., Kasperbauer J.L., et al. Merkel cell carcinoma of the head and neck: a retrospective case series. Head Neck 24 11 (2002) 982-988
20. Karapantzos I., Tsaroucha A., Polychronidis A., et al. Merkel cell carcinoma: report of seven cases. ORL J Otorhinolaryngol Relat Spec 65 6 (2003) 370-374
21. Suarez C., Rodrigo J.P., Ferlito A., et al. Merkel cell carcinoma of the head and neck. Oral Oncol 40 8 (2004) 773-779
22. Veness M.J., Palme C.E., and Morgan G.J. Merkel cell carcinoma: a review of management. Curr Opin Otolaryngol Head Neck Surg 16 2 (2008) 170-174
23. Gillenwater A.M., Hessel A.C., Morrison W.H., et al. Merkel cell carcinoma of the head and neck: effect of surgical excision and radiation on recurrence and survival. Arch Otolaryngol Head Neck Surg 127 2 (2001) 149-154
24. Lawenda B.D., Thiringer J.K., Foss R.D., et al. Merkel cell carcinoma arising in the head and neck: optimizing therapy. Am J Clin Oncol 24 1 (2001) 35-42
25. Dancey A.L., Rayatt S.S., Soon C., et al. Merkel cell carcinoma: a report of 34 cases and literature review. J Plast Reconstr Aesthet Surg 59 12 (2006) 1294-1299
26. Boyer J.D., Zitelli J.A., Brodland D.G., et al. Local control of primary Merkel cell carcinoma: review of 45 cases treated with Mohs micrographic surgery with and without adjuvant radiation. J Am Acad Dermatol 47 6 (2004) 885-892
27. Gollard R., Weber R., Kosty M.P., et al. Merkel cell carcinoma: review of 22 cases with surgical, pathologic, and therapeutic considerations. Cancer 88 8 (2000) 1842-1851
28. O'Connor W.J., Roenigk R.K., and Brodland D.G. Merkel cell carcinoma: comparison of Mohs micrographic surgery and wide excision in eighty six patients. Dermatol Surg 23 10 (1997) 929-933
29. McCarn K.E., and Park S.S. Lip reconstruction. Otolaryngol Clin North Am 40 2 (2007) 361-380
30. Kokosuka E.R., Kokoska M.S., Collins B.T., et al. Early aggressive treatment for Merkel cell carcinoma improves outcome. Am J Surg 174 (1997) 688-693
31. Mohs F.E. Chemosurgery: a microscopically controlled method of cancer excision. Arch Surg 42 (1941) 279-295
32. Zitell J.A., Brown C., and Hanusa B.H. Mohs micrographic surgery for the treatment of primary cutaneous melanoma. J Am Acad Dermatol 37 2, pt 1 (1997) 236-245
33. Clark G.S., Pappas-Plitis E.C., Cherpelis B.S., et al. Surgical management of melanoma in situ on chronically sun-damaged skin. Cancer Control 15 3 (2008) 216-224
34. Shriner D., McCoy D.K., Goldberg D.G., et al. Mohs micrographic surgery. J Am Acad Dermatol 39 1 (1998) 79-97
35. Mehrany K., Otley C.C., Weenig R.H., et al. A meta-analysis of the prognostic significance of sentinel lymph node status in Merkel cell carcinoma. Dermatol Surg 28 2 (2002) 113-117
36. McAfee W.J., Morris C.G., Mendenhall C.M., et al. Merkel cell carcinoma: treatment and outcomes. Cancer 104 8 (2005) 1761-1764
37. Senchenkov A., Barnes S.A., and Moran S.L. Predictors of survival and recurrence in the surgical treatment of Merkel cell carcinoma of the extremities. J Surg Oncol 95 3 (2007) 229-234
38. Messina J.L., Reintgen D.S., Cruse C.W., et al. Selective lymphadenectomy in patients with Merkel cell (cutaneous neuroendocrine) carcinoma. Ann Surg Oncol 4 5 (1997) 389-395
39. Goessling W., McKee P.H., and Mayer R.J. Merkel cell carcinoma. J Clin Oncol 20 2 (2002) 588-598
40. Lewis J.M., Zager J.S., Yu D., et al. Full-thickness grafts procured from skin overlying the sentinel lymph node basin; reconstruction of primary cutaneous malignancy excision defects. Ann Surg Oncol 15 6 (2008) 1733-1740
41. Moncrieff M.D., Bowen F., Thompson J.F., et al. Keystone flap reconstruction of primary melanoma excision defects of the leg-the end of the skin graft?. Ann Surg Oncol 15 10 (2008) 2867-2873
42. Henness S., and Vereecken P. Management of Merkel cell tumours: an evidence-based review. Curr Opin Oncol 20 3 (2008) 280-286
43. Gannon C.J., Rousseau D.L., Ross M.I., et al. Accuracy of lymphatic mapping and sentinel lymph node biopsy after previous wide local excision in patients with primary melanoma. Cancer 107 11 (2006) 2647-2652
44. Maza S., Trefzer U., Hofmann M., et al. Impact of sentinel lymph node biopsy in patients with Merkel cell carcinoma: results of a prospective study and review of the literature. Eur J Nucl Med Mol Imaging 33 4 (2006) 433-440
45. Hill A.D., Brady M.S., and Coit D.G. Intraoperative lymphatic mapping and sentinel lymph node biopsy for Merkel cell carcinoma. Br J Surg 86 4 (1999) 518-521
46. Morton D.L., Thompson J.F., Cochran A.J., et al. Sentinel-node biopsy or nodal observation in melanoma. N Engl J Med 355 13 (2006) 1307-1317
47. Warner R.E., Quinn M.J., Hruby G., et al. Management of Merkel cell carcinoma: the roles of lymphoscintigraphy, sentinel lymph node biopsy and adjuvant radiotherapy. Ann Surg Oncol 15 9 (2008) 2509-2518
48. McMasters K.M., Noyes R.D., Reintgen D.S., et al. Lessons learned from the Sunbelt Melanoma Trial. J Surg Oncol 86 4 (2004) 212-223
49. Conway W.C., Faries M.B., Nicholl M.B., et al. Age-related lymphatic dysfunction in melanoma patients. Ann Surg Oncol 16 6 (2009) 1548-1552
50. Scoggins C.R., Martin R.C., Ross M.I., et al. Factors associated with false-negative sentinel lymph node biopsy in melanoma patients: results from a prospective randomized trial. Ann Surg Oncol 16 Suppl 1 (2009) 3
51. Gupta S.G., Wang L.C., Penas P.F., et al. Sentinel Lymph Node Biopsy for Evaluation and Treatment of Patients with Merkel Cell Carcinoma: the Dana-Farber experience and meta-analysis of the literature. Arch Dermatol 142 6 (2006) 685-690
52. Pectasides D., Pectasides M., and Economopoulos T. Merkel cell cancer of the skin. Ann Oncol 17 10 (2006) 1489-1495
53. Sandel H.D., Day T., Richardson M.S., et al. Merkel cell carcinoma: does tumor size or depth of invasion correlate with recurrence, metastasis, or patient survival?. Laryngoscope 116 5 (2006) 791-795
54. Wagner J.D., Evdokimow D.Z., Weisberger E., et al. Sentinel node biopsy for high-risk nonmelanoma cutaneous malignancy. Arch Dermatol 140 1 (2004) 75-79
55. Sarnaik A.A., Zager J.S., Cox L.E., et al. Routine omission of sentinel lymph node biopsy for Merkel cell carcinoma ≤1 cm is not justified. J Clin Oncol 28 1 (2010) e7