Metabolism, gliomas, and IDH1

New England Journal of Medicine

Volumn 362, Issue 12, 2010, Pages 1144-

  Smeitink, Jan ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYGLUTARIC ACID; ISOCITRATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; BRAIN TUMOR; CARCINOGENESIS; DECARBOXYLATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; GENE MUTATION; GLIOBLASTOMA; GLIOMA; METABOLIC DISORDER; METABOLISM; MUTANT; PRIORITY JOURNAL; PROGNOSIS;

EID: 77950248589     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcibr0912922     Document Type: Article

References (5)

1. Dang L, White DW, Gross S, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 2009;462:739-744
2. Duran M, Kamerling P, Bakker HD, van Gennip AH, Wadman SK. L-2-hydroxyglutaric aciduria: an inborn error of metabolism? J Inherit Metab Dis 1980;3:109-112
3. Chalmers RA, Lawson AM, Watts RWE, et al. D-2-hydroxyglutaric aciduria: case report and biochemical studies. J Inherit Metab Dis 1980;3:11-15
4. Van Schaftingen E, Rzem R, Veiga-da-Cunha M. L-2-hydroxyglutaric aciduria, a disorder of metabolite repair. J Inherit Metab Dis 2009;32:135-142
5. Knaap MS, Jakobs C, Hoffmann GF, et al. D-2-hydroxyglu- 5. taric aciduria: further clinical delineation. J Inherit Metab Dis 1999;22:404-413