High level of protection induced by two fowlpox vector vaccines against a highly pathogenic avian influenza H5N1 challenge in specific-pathogen-free chickens

Avian Diseases

Volumn 54, Issue SUPPL. 1, 2010, Pages 257-261

  Bublot, Michel ^a   Manvell, Ruth J ^b   Shell, Wendy ^b   Brown, Ian H ^b  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b VETERINARY LABORATORIES AGENCY   (United Kingdom)

Author keywords

Avian influenza; Challenge; Fowlpox; H5N1; HPAI; TROVAC; Vaccination; Vector vaccine

Indexed keywords

INFLUENZA VACCINE; RECOMBINANT VACCINE;

ANIMAL; AVIAN INFLUENZA; CHICKEN; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FOWLPOX VIRUS; GERMFREE ANIMAL; IMMUNOLOGY; INFLUENZA VIRUS A H5N1; PATHOGENICITY; VIROLOGY; VIRUS SHEDDING;

ANIMALS; CHICKENS; FOWLPOX VIRUS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA IN BIRDS; INFLUENZA VACCINES; SPECIFIC PATHOGEN-FREE ORGANISMS; VACCINES, SYNTHETIC; VIRUS SHEDDING;

AVES; GALLUS GALLUS;

EID: 77950228890     PISSN: 00052086     EISSN: None     Source Type: Journal    
DOI: 10.1637/8774-033109-ResNote.1     Document Type: Conference Paper

References (18)

1. Bublot, M., N. Pritchard, D. E. Swayne, P. Selleck, K. Karaca, D. L. Suarez, J. C. Audonnet, and T. R. Mickle. Development and use of fowlpox vectored vaccines for avian influenza. Ann. N.Y. Acad. Sci. 1081:193-201. 2006.
2. Bublot, M., D. E. Swayne, P. Selleck, E. Montiel, N. Pritchard, M. Lee, and T. R. Mickle. TROVAC-AI H5, an avian influenza fowlpox vector vaccine, as an alternative vaccine for hatcheries. In: OIE/FAO International Scientific Conference on avian influenza. A. Schudel and M. Lombard, eds. Karger, Basel, Switzerland. pp. 248-249. 2006.
3. Bublot, M., F. X. Le Gros, D. Nieddu, N. Pritchard, T. R. Mickle, and D. E. Swayne. Efficacy of two H5N9-inactivated vaccines against challenge with a recent H5N1 highly pathogenic avian influenza isolate from a chicken in Thailand. Avian Dis. 51:332-337. 2007.
4. Bublot, M., N. Pritchard, J. S. Cruz, T. R. Mickle, P. Selleck, and D. E. Swayne. Efficacy of a fowlpox-vectored avian influenza H5 vaccine against Asian H5N1 highly pathogenic avian influenza virus challenge. Avian Dis. 51:498-500. 2007.
5. Bublot, M., K. Karaca, J. Minke, N. Pritchard, F. X. Le Gros, H. Poulet, J. C. Audonnet, D. Swayne, and B. Nordgren. Current influenza vaccines for poultry and other animal species. In: Immunobiology of influenza infection: approaches for an emerging zoonotic disease. R. Tripp, ed. Research Signpost, Kerala, India. pp. 117-136. 2008.
6. Capua, I., and S. Marangon. The use of vaccination as an option for the control of avian influenza. Avian Pathol. 32:335-343. 2003.
7. Capua, I., C. Terregino, G. Cattoli, and A. Toffan. Increased resistance of vaccinated turkeys to experimental infection with an H7N3 low-pathogenicity avian influenza virus. Avian Pathol. 33:158-163. 2004.
8. Ge, J., G. Deng, Z. Wen, G. Tian, Y. Wang, J. Shi, X. Wang, Y. Li, S. Hu, Y. Jiang, C. Yang, K. Yu, Z. Bu, and H. Chen. Newcastle disease virus-based live attenuated vaccine completely protects chickens and mice from lethal challenge of homologous and heterologous H5N1 avian influenza viruses. J. Virol. 81:150-158. 2007.
9. Romer-Oberdorfer, A., J. Veits, D. Helferich, and T. C. Mettenleiter. Level of protection of chickens against highly pathogenic H5 avian influenza virus with Newcastle disease virus based live attenuated vector vaccine depends on homology of H5 sequence between vaccine and challenge virus. Vaccine 26:2307-2313. 2008.
10. Spackman, E., D. A. Senne, L. L. Bulaga, S. Trock, and D. L. Suarez. Development of multiplex real-time RT-PCR as a diagnostic tool for avian influenza. Avian Dis. 47:1087-1090. 2003.
11. Steensels, M., M. Bublot, S. Van Borm, J. De Vriese, B. Lambrecht, A. Richard-Mazet, S. Chanavat-Bizzini, M. Duboeuf, F. X. Le Gros, and T. van den Berg. Prime-boost vaccination with a fowlpox vector and an inactivated avian influenza vaccine is highly immunogenic in Pekin ducks challenged with Asian H5N1 HPAI. Vaccine 27:646-654. 2009.
12. Swayne, D. E., J. R. Beck, and T. R. Mickle. Efficacy of recombinant fowl poxvirus vaccine in protecting chickens against a highly pathogenic Mexican-origin H5N2 avian influenza virus. Avian Dis. 41:910-922. 1997.
13. Swayne, D. E., M. Garcia, J. R. Beck, N. Kinney, and D. L. Suarez. Protection against diverse highly pathogenic H5 avian influenza viruses in chickens immunized with a recombinant fowlpox vaccine containing an H5 avian influenza hemagglutinin gene insert. Vaccine 18:1088-1095. 2000.
14. Swayne, D. E., M. L. Perdue, J. R. Beck, M. Garcia, and D. L. Suarez. Vaccines protect chickens against H5 highly pathogenic avian influenza in the face of genetic changes in field viruses over multiple years. Vet. Microbiol. 74:165-172. 2000.
15. Swayne, D. E., G. Avellaneda, T. R. Mickle, N. Pritchard, J. Cruz, and M. Bublot. Improvements to the hemagglutination inhibition test for serological assessment of recombinant fowlpox-H5-avian-influenza vaccination in chickens and its use along with an agar gel immunodiffusion test for differentiating infected from noninfected vaccinated animals. Avian Dis. 51:697-704. 2007.
16. van den Berg, T., B. Lambrecht, S. Marche, M. Steensels, S. Van Borm, and M. Bublot. Influenza vaccines and vaccination strategies in birds. Comp. Immunol. Microbiol. Infect. Dis. 31:121-165. 2008.
17. Veits, J., D. Wiesner, W. Fuchs, B. Hoffmann, H. Granzow, E. Starick, E. Mundt, H. Schirrmeier, T. Mebatsion, T. C. Mettenleiter, and A. Romer-Oberdorfer. Newcastle disease virus expressing H5 hemagglutinin gene protects chickens against Newcastle disease and avian influenza. Proc. Natl. Acad. Sci. U. S. A. 103:8197-8202. 2006.
18. WHO/OIE/FAO, and H5N1 Evolution Working Group, Continuing progress towards a unified nomenclature for the highly pathogenic H5N1 avian influenza viruses: divergence of clade 2.2 viruses. Influenza Other Respi. Viruses 3:59-62. 2009.