Survival of infants in the context of prevention of mother to child HIV transmission in South Africa

Acta Paediatrica, International Journal of Paediatrics

Volumn 99, Issue 5, 2010, Pages 694-698

  Chopra, M ^a,b,c   Doherty, T ^a,b,c   Goga, A ^a,d   Jackson, D ^c   Persson, L A ^b  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF THE WESTERN CAPE   (South Africa)

^d SEFAKO MAKGATHO HEALTH SCIENCES UNIVERSITY   (South Africa)

Author keywords

Infant mortality; Mother to child transmission of HIV; Paediatric HIV

Indexed keywords

NEVIRAPINE; VIRUS DNA;

ARTICLE; CHILD DEATH; COHORT ANALYSIS; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION PREVENTION; MAJOR CLINICAL STUDY; NEWBORN; NEWBORN MORTALITY; PERINATAL PERIOD; POLYMERASE CHAIN REACTION; PRENATAL EXPOSURE; PRENATAL PERIOD; PRIORITY JOURNAL; PROGNOSIS; QUESTIONNAIRE; RISK FACTOR; RURAL AREA; SINGLE DRUG DOSE; SOUTH AFRICA; SURVIVAL RATE; VIRUS TRANSMISSION;

DNA, VIRAL; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; INFANT MORTALITY; INFANT, NEWBORN; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; KAPLAN-MEIERS ESTIMATE; MALE; POLYMERASE CHAIN REACTION; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; QUESTIONNAIRES; RISK FACTORS; SOUTH AFRICA;

EID: 77950217070     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2009.01675.x     Document Type: Article

References (16)

1. Newell ML, Coovadia H, Cortina-Borja M, Rollins N, Gaillard P, Dabis F. Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis. Lancet 2004 364 : 1236 1243.
2. Marinda E, Humphrey JH, Iliff PJ, Mutasa K, Nathoo KJ, Piwoz EG, et al. Child mortality according to maternal and infant HIV status in Zimbabwe. Pediatr Infect Dis J 2007 26 : 519 526.
3. Obimbo EM, Mbori-Ngacha DA, Ochieng JO, Richardson BA, Otieno PA, Bosire R, et al. Predictors of early mortality in a cohort of human immunodeficiency virus type 1-infected African children. Pediatr Infect Dis J 2004 23 : 536 543.
4. Kurewa EN, Gumbo FZ, Munjoma MW, Mapingure MP, Chirenje MZ, Rusakaniko S, et al. Effect of maternal HIV status on infant mortality: evidence from a 9-month follow-up of mothers and their infants in Zimbabwe. J Perinatol 2009 August 20 [Epub ahead of print].
5. Brahmbhatt H, Kigozi G, Wabwire-Mangen F, Serwadda D, Lutalo T, Nalugoda F, et al. Mortality in HIV-infected and uninfected children of HIV-infected and uninfected mothers in rural Uganda. J Acquir Immune Defic Syndr 2006 41 : 504 508.
6. Filteau S. The HIV-exposed, uninfected African child. Trop Med Int Health 2009 14 : 276 287.
7. Guay LA, Musoke P, Fleming T, Bagenda D, Allen M, Nakabiito C, et al. Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial. Lancet 1999 354 : 795 802.
8. Jackson DJ, Chopra M, Doherty TM, Colvin MS, Levin JB, Willumsen JF, et al. Operational effectiveness and 36 week HIV-free survival in the South African programme to prevent mother-to-child transmission of HIV-1. AIDS 2007 21 : 509 516.
9. Doherty T, Chopra M, Jackson D, Goga A, Colvin M, Persson LA. Effectiveness of the WHO/UNICEF guidelines on infant feeding for HIV-positive women: results from a prospective cohort study in South Africa. AIDS 2007 21 : 1791 1797.
10. Mbori-Ngacha D, Nduati R, John G, Reilly M, Richardson B, Mwatha A, et al. Morbidity and mortality in breastfed and formula-fed infants of HIV-1-infected women: a randomized clinical trial. JAMA 2001 286 : 2413 2420.
11. Fox MP, Brooks D, Kuhn L, Aldrovandi G, Sinkala M, Kankasa C, et al. Reduced mortality associated with breast-feeding-acquired HIV infection and breast-feeding among HIV-infected children in Zambia. J Acquir Immune Defic Syndr 2008 48 : 90 6.
12. Mphatswe W, Blanckenberg N, Tudor-Williams G, Prendergast A, Thobakgale C, Mkhwanazi N, et al. High frequency of rapid immunological progression in African infants infected in the era of perinatal HIV prophylaxis. AIDS 2007 21 : 1253 1261.
13. Doherty T, Chopra M, Nsibande D, Mngoma D. Improving the coverage of the PMTCT programme through a participatory quality improvement intervention in South Africa. BMC Public Health 2009 9 : 406.
14. Violari A, Cotton MF, Gibb DM, Babiker AG, Steyn J, Madhi SA, et al. Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med 2008 359 : 2233 2244.
15. Chintu PC, Bhat G, Walker A, Mulenga V, Sinyinza F, Lishimpi K, et al. Co-trimoxazole as prophylaxis against opportunistic infections in HIV-infected Zambian children (CHAP): a double-blind randomised placebo-controlled trial. Lancet 2004 364 : 1865 1871.
16. World Health Organisation. Rapid advice: use of antiretroviral drugs for treating pregnant women and preventing HIV infection in infants. Geneva : WHO, 2009.