Examination of Type IV Pilus Expression and Pilus-Associated Phenotypes in Kingella kingae Clinical Isolates

Infection and Immunity

Volumn 78, Issue 4, 2010, Pages 1692-1699

  Kehl Fie, Thomas E ^a,b   Porsch, Eric A ^b   Yagupsky, Pablo ^c   Grass, Elizabeth A ^b   Obert, Caroline ^d   Benjamin Jr , Daniel K ^b   St Geme III, Joseph W ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; PILA1 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIGENIC VARIATION; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM ADHERENCE; BACTERIUM COLONY; BACTERIUM ISOLATE; BACTERIUM PILUS; BLOOD; BONE; CHILD; CONTROLLED STUDY; ENDOCARDITIS; GENETIC VARIABILITY; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOREACTIVITY; IN VITRO STUDY; KINGELLA KINGAE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRAIN DIFFERENCE; SYNOVIAL FLUID;

ANTIBODIES, BACTERIAL; ARTHRITIS, INFECTIOUS; BACTERIAL ADHESION; BACTERIAL PROTEINS; CARRIER STATE; DNA, BACTERIAL; FIMBRIAE PROTEINS; FIMBRIAE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; KINGELLA KINGAE; MOLECULAR SEQUENCE DATA; NEISSERIACEAE INFECTIONS; OSTEOMYELITIS; PHENOTYPE; POLYMORPHISM, GENETIC; RESPIRATORY TRACT INFECTIONS; SEQUENCE ANALYSIS, DNA;

EID: 77950199221     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00908-09     Document Type: Article

References (33)

1. Anonymous. 2004. Osteomyelitis/septic arthritis caused by Kingella kingae among day care attendees - Minnesota, 2003. MMWR Morb. Mortal. Wkly. Rep. 53:241-243.
2. Burrows, L. L. 2005. Weapons of mass retraction. Mol. Microbiol. 57:878-888.
3. Chometon, S., Y. Benito, M. Chaker, S. Boisset, C. Ploton, J. Berard, F. Vandenesch, and A. M. Freydiere. 2007. Specific real-time polymerase chain reaction places Kingella kingae as the most common cause of osteoarticular infections in young children. Pediatr. Infect. Dis. J. 26:377-381.
4. Craig, L., M. E. Pique, and J. A. Tainer. 2004. Type IV pilus structure and bacterial pathogenicity. Nat. Rev. Microbiol. 2:363-378.
5. Froholm, L. O., and K. Bovre. 1972. Fimbriation associated with the spreading-corroding colony type in Moraxella kingii. Acta Pathol. Microbiol. Scand. B Microbiol. Immunol. 80:641-648.
6. Gené, A., J. J. Garcia-Garcia, P. Sala, M. Sierra, and R. Huguet. 2004. Enhanced culture detection of Kingella kingae, a pathogen of increasing clinical importance in pediatrics. Pediatr. Infect. Dis. J. 23:886-888.
7. Harrison, O. B., B. D. Robertson, S. N. Faust, M. A. Jepson, R. D. Goldin, M. Levin, and R. S. Heyderman. 2002. Analysis of pathogen-host cell interactions in purpura fulminans: expression of capsule, type IV pili, and PorA by Neisseria meningitidis in vivo. Infect. Immun. 70:5193-5201.
8. Heckels, J. E. 1989. Structure and function of pili of pathogenic Neisseria species. Clin. Microbiol. Rev. 2(Suppl.):S66-S73.
9. Henriksen, S. D. 1969. Corroding bacteria from the respiratory tract. 1. Moraxella kingii. Acta Pathol. Microbiol. Scand. 75:85-90.
10. Henriksen, S. D., and K. Bovre. 1968. Moraxella kingii sp. nov., a haemolytic, saccharolytic species of the genus Moraxella. J. Gen. Microbiol. 51:377-385.
11. Kehl-Fie, T. E., S. E. Miller, and J. W. St. Geme III. 2008. Kingella kingae expresses type IV pili that mediate adherence to respiratory epithelial and synovial cells. J. Bacteriol. 190:7157-7163.
12. 54, PilS, and PilR. J. Bacteriol. 191:4976-4986.
13. Kehl-Fie, T. E., and J. W. St. Geme III. 2007. Identification and characterization of an RTX toxin in the emerging pathogen Kingella kingae. J. Bacteriol. 189:430-436.
14. Kiang, K. M., F. Ogunmodede, B. A. Juni, D. J. Boxrud, A. Glennen, J. M. Bartkus, E. A. Cebelinski, K. Harriman, S. Koop, R. Faville, R. Danila, and R. Lynfield. 2005. Outbreak of osteomyelitis/septic arthritis caused by Kingella kingae among child care center attendees. Pediatrics 116:e206-e213.
15. Mårdh, P. A., and L. Westtom. 1976. Adherence of bacterial to vaginal epithelial cells. Infect. Immun. 13:661-666.
16. Mattick, J. S. 2002. Type IV pili and twitching motility. Annu. Rev. Microbiol. 56:289-314.
17. Moumile, K., J. Merckx, C. Glorion, P. Berche, and A. Ferroni. 2003. Osteoarticular infections caused by Kingella kingae in children: contribution of polymerase chain reaction to the microbiologic diagnosis. Pediatr. Infect. Dis. J. 22:837-839.
18. Obert, C. A., G. Gao, J. Sublett, E. I. Tuomanen, and C. J. Orihuela. 2007. Assessment of molecular typing methods to determine invasiveness and to differentiate clones of Streptococcus pneumoniae. Infect. Genet. Evol. 7:708-716.
19. Punsalang, A. P., Jr., and W. D. Sawyer. 1973. Role of pili in the virulence of Neisseria gonorrhoeae. Infect. Immun. 8:255-263.
20. Saiman, L., K. Ishimoto, S. Lory, and A. Prince. 1990. The effect of piliation and exoproduct expression on the adherence of Pseudomonas aeruginosa to respiratory epithelial monolayers. J. Infect. Dis. 161:541-548.
21. Sjölinder, H., and A. B. Jonsson. 2007. Imaging of disease dynamics during meningococcal sepsis. PLoS One 2:e241.
22. Slonim, A., E. S. Walker, E. Mishori, N. Porat, R. Dagan, and P. Yagupsky. 1998. Person-to-person transmission of Kingella kingae among day care center attendees. J. Infect. Dis. 178:1843-1846.
23. Swanson, J. 1973. Studies on gonococcus infection. IV. Pili: their role in attachment of gonococci to tissue culture cells. J. Exp. Med. 137:571-589.
24. Trust, T. J., R. M. Gillespie, A. R. Bhatti, and L. A. White. 1983. Differences in the adhesive properties of Neisseria meningitidis for human buccal epithelial cells and erythrocytes. Infect. Immun. 41:106-113.
25. Verdier, I., A. Gayet-Ageron, C. Ploton, P. Taylor, Y. Benito, A. M. Freydiere, F. Chotel, J. Berard, P. Vanhems, and F. Vandenesch. 2005. Contribution of a broad range polymerase chain reaction to the diagnosis of osteoarticular infections caused by Kingella kingae: description of twenty-four recent pediatric diagnoses. Pediatr. Infect. Dis. J. 24:692-696.
26. Ward, M. E., P. J. Watt, and J. N. Robertson. 1974. The human fallopian tube: a laboratory model for gonococcal infection. J. Infect. Dis. 129:650-659.
27. Yagupsky, P. 2004. Kingella kingae: from medical rarity to an emerging paediatric pathogen. Lancet Infect. Dis. 4:358-367.
28. Yagupsky, P., R. Dagan, C. W. Howard, M. Einhorn, I. Kassis, and A. Simu. 1992. High prevalence of Kingella kingae in joint fluid from children with septic arthritis revealed by the BACTEC blood culture system. J. Clin. Microbiol. 30:1278-1281.
29. Yagupsky, P., R. Dagan, F. Prajgrod, and M. Merires. 1995. Respiratory carriage of Kingella kingae among healthy children. Pediatr. Infect. Dis. J. 14:673-678.
30. Yagupsky, P., Y. Erlich, S. Ariela, R. Trefler, and N. Porat. 2006. Outbreak of Kingella kingae skeletal system infections in children in daycare. Pediatr. Infect. Dis. J. 25:526-532.
31. Yagupsky, P., N. Peled, and O. Katz. 2002. Epidemiological features of invasive Kingella kingae infections and respiratory carriage of the organism. J. Clin. Microbiol. 40:4180-4184.
32. Yagupsky, P., N. Porat, and E. Pinco. 2009. Pharyngeal colonization by Kingella kingae in children with invasive disease. Pediatr. Infect. Dis. J. 28:155-157.
33. Yagupsky, P., and A. Slonim. 2005. Characterization and immunogenicity of Kingella kingae outer-membrane proteins. FEMS Immunol. Med. Microbiol. 43:45-50.