Drug therapy for delirium in terminally ill adult patients

Cochrane Database of Systematic Reviews

Volumn , Issue 4, 2009, Pages

  Jackson, Kenneth C ^a   Lipman, Arthur G ^b  

^a PACIFIC UNIVERSITY   (United States)

^b UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

Antipsychotic agents therapeutic use ; Chlorpromazine therapeutic use ; Delirium *drug therapy; etiology ; Haloperidol therapeutic use ; Humans; Lorazepam therapeutic use ; Terminally ill *psychology

Indexed keywords

ALPRAZOLAM; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; BENZODIAZEPINE DERIVATIVE; BUSPIRONE; CHLORPROMAZINE; HALOPERIDOL; HYDROXYZINE; LEVOMEPROMAZINE; NEUROLEPTIC AGENT; OLANZAPINE; RISPERIDONE; THIORIDAZINE;

ANXIETY DISORDER; DRUG EFFICACY; HUMAN; PALLIATIVE THERAPY; REVIEW; SYSTEMATIC REVIEW; TERMINALLY ILL PATIENT; TREATMENT OUTCOME;

EID: 77950166139     PISSN: 1469493X     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD004770     Document Type: Review

References (33)

1. Breitbart 1996a {published data only} Breitbart W, Rocco M, Platt M, Weissman H, Derevenco M, Grau C, et al.A double-blind trial of haloperidol, chlorpromazine, and lorazepam in the treatment of delirium in hospitalized AIDS patients. American Journal of Psychiatry 1996;153(2):231-7.
2. Adams 1984 {published data only} Adams F. Neuropsychiatric evaluation and treatment of delirium in the critically ill cancer patient. The Cancer Bulletin 1984;36(3):156-60.
3. Adams 1986 {published data only} Adams F, Fernandez F, Andersson BS. Emergency pharmacotherapy of delirium in the critically ill cancer patient. Psychosomatics 1986;27(1):33-8.
4. Akechi 1996 {published data only} Akechi T, Uchitomi Y, Okamura H, Fukue M, Kagaya A, Nishida A, et al.Usage of haloperidol for delirium in cancer patients. Supportive Care in Cancer Cancer 1996;4:390-2.
5. Breitbart 2002 {published data only} Breitbart W, Tremblay A, Gibson C. An open trial of olanzapine for the treatment of delirium in hospitalized cancer patients. Psychosomatics 2002;43(3):175-82.
6. Burke 1991 {published data only} Burke AL, Diamond PL, Hulbert J, Yeatman J, Farr EA. Terminal restlessness - its management and the role of midazolam. The Medical Journal of Australia 1991;155:485- 7.
7. Cobb 2000 {published data only} Cobb JL, Glantz MJ, Nicholas PK, Martin EW, Paul-Simon A, Cole BF, et al.Delirium in patients with cancer at the end of life. Cancer Practice 2000;8(4):172-7.
8. Fainsinger 2000 {published data only} Fainsinger RL, De Moissac D, Mancini I, Oneschuk D. Sedation for delirium and other symptoms in terminally ill patients in Edmonton. Journal of Palliative Care 2000;16(2):5-10.
9. Lawlor 2000 {published data only} Lawlor PG, Gagnon B, Mancini IL, Pereira JL, Hanson J, Suarez-Almazor ME, et al.Occurrence, causes, and outcome of delirium in patients with advanced cancer. Archives of Internal Medicine 2000;160:786-94.
10. McIver 1994 {published data only} McIver B, Walsh D, Nelson K. The use of chlorpromazine for symptom control in dying cancer patients. Journal of Pain and Symptom Management 1994;9(5):341-5.
11. Oliver 1985 {published data only} Oliver DJ. The use of methotrimeprazine in terminal care. The British Journal of Clinical Practice 1985;39(9):339-40.
12. Olofsson 1996 {published data only} Olofsson SM, Weitzner MA, Valentine AD, Baile WF, Meyers CA. A retrospective study of the psychiatric management and outcome of delirium in the cancer patient. Supportive Care in Cancer 1996;4:351-7.
13. Pereira 1997 {published data only} Pereira J, Hanson J, Bruera E. The frequency and clinical course of cognitive impairment in patients with terminal cancer. Cancer 1997;79:835-42.
14. Stiefel 1992 {published data only} Stiefel F, Fainsinger R, Bruera E. Acute confusional states in patients with advanced cancer. Journal of Pain and Symptom Management 1992;7(2):94-8.
15. APA 1995 American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th Edition. Arlington, VA: American Psychiatric Publishing, Inc, 1995.
16. Bluestine 1994 Bluestine S, Lesko L. Psychotropic medications in oncology and in AIDS patients. Advances in Psychosomatic Medicine 1994;21:107-37.
17. Breitbart 1996b Breitbart W, Jacobsen PB. Psychiatric symptom management in terminal care. Clinics in Geriatric Medicine 1996;12:329-47.
18. Breitbart 1998 Breitbart W, Chochinov HM, Passik SD. Psychiatric aspects of palliative care. In: Doyle D, Hanks GWC, MacDonald N editor (s). Oxford Textbook of Palliative Medicine. 2nd Edition. New Yord: Oxford University Press, 1998:933-56.
19. Breitbart 2000 Breitbart W, Strout D. Delirium in the terminally ill. Clinics in Geriatric Medicine 2000;16(2):357-72.
20. Caraceni 1995 Caraceni A. Delirium in palliative care. European Journal of Palliative Care 1995;2:62-7.
21. Cochrane 2003 Mulrow CD, Oxman AD, editors. The Cochrane Reviewers' Handbook [updated February 2003]. In: The Cochrane Library [database on CDROM]. The Cochrane Collaboration. Oxford: Update Software; 2003, Issue 2.
22. de Stoutz 1995 de Stoutz ND, Tapper M, Fainsinger RL. Reversible delirium in terminally ill patients. Journal of Pain and Symptom Management 1995;10:249-53.
23. Fainsinger 1992 Fainsinger R, Bruera E. Treatment of delirium in terminally ill patients. Journal of Pain and Symptom Management 1992;7:54-6.
24. Fainsinger 1993 Fainsinger RL, Tapper M, Bruera E. A perspective on the management of delirium in terminally ill patients on a palliative care unit. Journal of Palliative Care 1993;9:4-8.
25. Ingham 1998 Ingham JM, Caraceni AT. Delirium. In: Berger AM, Portenoy RK, Weissman DE editor(s). Principles and Practices of Supportive Oncology. Philadelphia, PA: Lippincott-Raven, 1998:477-96.
26. Jackson 1999 Jackson KC, Lipman AG. Delirium in palliative care patients. J Pharm Care Pain Sympt Cont 1999;7(4):59-70.
27. Jadad 1996 Jadad AR, Moore RA, Carroll D, et al.Assessing the quality of reports of randomized clinical trials: is blinding necessary. Controlled Clinical Trials 1996;17(1):1-12.
28. Massie 1987 Massie MJ, Holland JC. The cancer patient with pain: psychiatric complications and their management. Medical Clinics of North America 1987;71:243-58.
29. Passik 1999 Passik SK, Cooper M. Complicated delirium in a cancer patient successfully treated with olanzapine. Journal of Pain and Symptom Management 1999;17(3):219-23.
30. Roth 1996 Roth AJ, Breitbart W. Psychiatric emergencies in terminally ill cancer patients. Pain and Palliat Care 1996;10:235-59.
31. Shapiro 1995 Shapiro BA, Warren J, Egol AB, et al.Practice parameters for intravenous analgesia and sedation for adult patients in the intensive care unit: an executive summary. Critical Care Medicine 1995;23:1596-600.
32. Smith 1995 Smith MJ, Breitbart WS, Platt MM. A critique of instruments and methods used to detect, diagnose, and rate delirium. Journal of Pain and Symptom Management 1995;10:35-77.
33. Stiefel 1994 Stiefel F, Razavi. Common psychiatric disorders in cancer patients II. Anxiety and acute confusional states. Supportive Care in Cancer 1994;2:233-7.