Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease

Cochrane Database of Systematic Reviews

Volumn , Issue 4, 2009, Pages

  Hirst, Ceri ^a   Owusu Ofori, Shirley ^b  

^a ASTRAZENECA   (United Kingdom)

^b KOMFO ANOKYE TEACHING HOSPITAL   (Ghana)

Author keywords

*Antibiotic prophylaxis; Adolescent; Anemia, sickle cell *complications ; Beta thalassemia complications ; Child; Hemoglobin SC disease complications ; Humans; Penicillins *therapeutic use ; Pneumococcal infections *prevention control ; Randomized controlled trials as topic

Indexed keywords

HAEMOPHILUS INFLUENZAE TYPE B VACCINE; PENICILLIN DERIVATIVE; PENICILLIN V; PLACEBO;

ALLERGIC REACTION; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC RESISTANCE; BACTEREMIA; BACTERIAL MENINGITIS; CHILD; CHILDHOOD MORTALITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FEVER; HUMAN; INCIDENCE; INFECTION RISK; INJECTION SITE REACTION; NAUSEA AND VOMITING; PNEUMOCOCCAL INFECTION; RANDOMIZED CONTROLLED TRIAL; REVIEW; RISK REDUCTION; SICKLE CELL ANEMIA; STATISTICAL ANALYSIS; STREPTOCOCCUS PNEUMONIAE; VACCINATION;

EID: 77950129825     PISSN: 1469493X     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD003427     Document Type: Review

References (31)

1. John 1984 {published data only} John AB, Ramlal A, Jackson H, Maude GH, Sharma AW, Serjeant GR. Prevention of pneumococcal infection in children with homozygous sickle cell disease. British Medical Journal (Clinical Research Edition) 1984;288(6430):1567-70.
2. PROPS 1986 {published data only} Gaston MH, Verter J. Sickle cell anaemia trial. Statistics in Medicine 1990;9(1-2):45- 51.
3. * Gaston MH, Verter JI, Woods G, Pegelow C, Kelleher J, Presbury G, et al.Prophylaxis with oral penicillin in children with sickle cell anemia: a randomized trial. New England Journal of Medicine 1986; 314(25):1593-9.
4. PROPS II 1995 {published data only} Bjornson AB, Falletta JM, Verter JI, Buchanan GR, Miller ST, Pegelow CH, et al.Serotype-specific immunoglobulin G antibody responses to pneumococcal vaccine in children with sickle cell anemia: effects of continued penicillin prophylaxis. Journal of Pediatrics 1996;129(6):828-35.
5. Falletta JM, Woods GM, Verter JI, Buchanan GR, Pegelow CH, Iyer RV, et al.Discontinuing penicillin prophylaxis in children with sickle cell anemia. Prophylactic Penicillin Study II. Journal of Pediatrics 1995;127(5):685-90.
6. Woods GM, Jorgensen JH, Waclawiw MA, Reid C, Wang W, Pegelow CH, et al.Influence of penicillin prophylaxis on antimicrobial resistance in nasopharyngeal S. pneumoniae among children with sickle cell anemia. The Ancillary Nasopharyngeal Culture Study of Prophylactic Penicillin Study II. Journal of Pediatric Hematology/Oncology 1997;19(4):327-33.
7. Berkovitch 1998 {published data only} Berkovitch M, Papadouris D, Shaw D, Onuaha N, Dias C, Olivieri NF. Trying to improve compliance with prophylactic penicillin therapy in children with sickle cell disease. British Journal of Clinical Pharmacology 1998;45(6):605- 7.
8. Lewthwaite 1962 {published data only} Lewthwaite CJ. A trial of chemoprophylaxis in sickle cell anaemia. Preliminary communication.. East African Medical Journal 1962;39 (5):196-9.
9. Anglin 1984 Anglin DL, Siegel JD, Pacini DL, Smith SJ, Adams G, Buchanan G. Effect of penicillin prophylaxis on nasopharyngeal colonization with Streptococcus pneumoniae in children with sickle cell anemia. Journal of Pediatrics 1984;104(1):18-22.
10. Black 2000 Black S, Shinefield H, Fireman B, Lewis P, Ray P, Hansen JR, et al.Efficacy, safety and immunogenicity of hepavalent pneumococcal conjugated vaccine in children. Northern California Kaiser Permanente Vaccine Study Center Group. Pediatric Infectious Disease Journal 2000;19(3):187-95.
11. BNF 2001 British Medical Association, Royal Pharmaceutical Society of Great Britain. British National Formulary. 42. London: BMJ Books, 2001.
12. Chesney 1992 Chesney PJ. The escalating problem of antimicrobial resistance in Streptococcus pneumoniae. American Journal of Diseases of Children 1992;146(8):912-6.
13. Cummins 1991 Cummins D, Heuschkel R, Davies SC. Penicillin prophylaxis in children with sickle cell disease in Brent. BMJ 1991;302(6783): 989-90.
14. Davies 1997 Davies SC, Oni L. The management of patients with sickle cell disease. BMJ 1997;315(7109):656-60.
15. Davies 2004 Davies GE, Hirst C, Lottenberg R, Dower N. Pneumococcal vaccines for sickle cell disease (Cochrane Review). Cochrane Database of Systematic Reviews 2004, Issue 1. [DOI: 10.1002/ 14651858]
16. Daw 1997 Daw NC, Wilimas JA, Wang WC, Presbury GJ, Joyner RE, Harris SC, et al.Nasopharyngeal carriage of penicillin resistant Streptococcus Pneumoniae in children with sickle cell disease. Pediatrics 1997;99(4):E7.
17. Ginsburg 1982 Ginsburg CM, McCracken GH, Zweighaft TC. Serum penicillin concentrations after intramuscular administration of benzathine penicillin G in children. Pediatrics 1982;69(4):452-4.
18. Hickman 1999 Hickman M, Modell B, Greengross P, Chapman C, Layton M, Falconer S, et al.Mapping the prevalence of sickle cell and beta thalassaemia in England: estimating and validating ethnic-specific rates. British Journal of Haematology 1999;104(4):860-7.
19. Klugman 2003 Klugman KP, Madhi SA, Huebner RE, Kohberger R, Mbelle N, Pierce N, et al.A trial of 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection. New England Journal of Medicine 2003;349(14):1341-8.
20. Lee 1995 Lee A, Thomas P, Cupidore L, Serjeant B, Serjeant G. Improved survival in homozygous sickle cell disease: lessons from a cohort study. BMJ 1995;311(7020):1600-2.
21. Lees 2000 Lees CM, Davies S, Dezateux C. Neonatal screening for sickle cell disease (Cochrane Review). Cochrane Database of Systematic Reviews 2000, Issue 1. [DOI: 10.1002/14651858; : Cochrane Library Number CD001913]
22. Leikin 1989 Leikin SL, Gallagher D, Kinney TR, Sloane D, Klug P, Rida W. Mortality in children and adolescents with sickle cell disease. Cooperative Study of Sickle Cell Disease. Pediatrics 1989;84(3): 500-8.
23. Lobel 1982 Lobel JS, Bove KE. Clinicopathologic characteristics of septicaemia in sickle cell disease. American Journal of Diseases of Children 1982; 136(6):543-7.
24. Pai 2000 Pai VB, Nahata MC. Duration of penicillin prophylaxis in sickle cell anemia: issues and controversies. Pharmacotherapy 2000;20(1): 110-7.
25. Platt 1994 Platt OS, Brambilla DJ, Rosse WF, Milner PF, Castro O, Steinberg MH, et al.Mortality in sickle cell disease: life expectancy and risk factors for early death. New England Journal of Medicine 1994;330 (23):1639-44.
26. Robinson 1966 Robinson MG, Watson RJ. Pneumococcal meningitis in sickle-cell anemia. The New England Journal of Medicine 1966;274(18):1006-8.
27. Robinson 2001 Robinson KA, Baughman W, Rothrock G, Barrett NL, Pass M, Lexau C, et al.Epidemiology of invasive Streptococcus pneumoniae infections in the United States, 1995-1998. Opportunities for prevention in the conjugate vaccine era.. JAMA 2001;285(13):1729-35.
28. Schulz 1995 Schulz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA 1995;273 (5):408-12.
29. Serjeant 2001 Serjeant GR, Serjeant BE. The immune system. Sickle Cell Disease. 3rd Edition. Oxford University Press, 2001:153-66.
30. Woods 1997 Woods GM, Jorgensen JH, Waclawiw MA, Reid C, Wang W, Pegelow CH, et al.Influence of penicillin prophylaxis on antimicrobial resistance in nasopharyngeal S. pneumoniae among children with sickle cell anemia. The Ancillary Nasopharyngeal Culture Study of Prophylactic Penicillin Study II. Journal of Pediatric Hematology/Oncology 1997;19(4):327- 33.
31. Zarkowsky 1986 Zarkowsky HS, Gallagher D, Gill FM, Wang WC, Falletta JM, Lande WM, et al.Bacteremia in sickle hemoglobinopathies. Journal of Pediatrics 1986;109(4):579-85.