DNA methylation does not regulate JUNB expression in CML: Comment on " Downregulation of JUNB mRNA expression in advanced phase chronic myelogenous leukemia" by Hoshino et al. [Leuk. Res. 33 (2009) 1361-1366]

Leukemia Research

Volumn 34, Issue 5, 2010, Pages 685-686

  Strathdee, Gordon ^a   Ferguson, Stuart ^a   Sim, Alyson ^b   Brown, Robert ^c  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

CML; DNA methylation; Epigenetics; JUNB

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HOXA4; TRANSCRIPTION FACTOR HOXA5; TRANSCRIPTION FACTOR JUNB; UNCLASSIFIED DRUG;

BLAST CELL CRISIS; BLOOD SAMPLING; CHRONIC MYELOID LEUKEMIA; CPG ISLAND; DNA METHYLATION; DOWN REGULATION; HUMAN; LETTER; NUCLEOTIDE SEQUENCE; PHILADELPHIA CHROMOSOME POSITIVE CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION SITE;

BLAST CRISIS; DNA METHYLATION; DOWN-REGULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-JUN; RNA, MESSENGER;

EID: 77950085719     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2009.11.016     Document Type: Letter

References (4)

1. Hoshino K., Quintas-Cardama A., Radich J., Dai H., Yang H., Garcia-Manero G. Downregulation of JUNB mRNA expression in advanced phase chronic myelogenous leukemia. Leukemia Research 2009, 33(October):1361-1366.
2. Yang M.Y., Liu T.C., Chang J.G., Lin P.M., Lin S.F. JunB gene expression is inactivated by methylation in chronic myeloid leukemia. Blood 2003, 101:3205-3211.
3. Strathdee G., Holyoake T.L., Sim A., Parker A., Oscier D.G., Melo J.V., et al. Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis. Clinical Cancer Research 2007, 13:5048-5055.
4. Passegue E., Jochum W., Schorpp-Kistner M., Mohle-Steinlein U., Wagner E.F. Chronic myeloid leukemia with increased granulocyte progenitors in mice lacking junB expression in the myeloid lineage. Cell 2001, 104:21-32.