Fullerene derivatives induce premature senescence: A new toxicity paradigm or novel biomedical applications

Toxicology and Applied Pharmacology

Volumn 244, Issue 2, 2010, Pages 130-143

  Gao, Jun ^a   Wang, Hsing Lin ^a   Shreve, Andrew ^a   Iyer, Rashi ^a  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

Cell cycle arrest; Cellular senescence; Engineered nanomaterials; Fullerenes; HERC5; Reactive oxygen species

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; FULLERENE DERIVATIVE; GAMMA CYCLODEXTRIN; HEXA CARBOXYL FULLERENE ADDUCT; NANOMATERIAL; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TRIS CARBOXYL FULLERENE ADDUCT; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIOMEDICINE; CELL AGING; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL ENCAPSULATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MOLECULAR MECHANICS; PHYSICAL CHEMISTRY; PREMATURE AGING; RNA EXTRACTION; WESTERN BLOTTING;

AGING; AGING, PREMATURE; APOPTOSIS; BIOMEDICAL ENGINEERING; CELL AGING; CELL CYCLE; CELL SURVIVAL; CELLS, CULTURED; FULLERENES; HUMANS; KERATINOCYTES;

BACTERIA (MICROORGANISMS);

EID: 77950050597     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.12.025     Document Type: Article

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