Preparation and in vitro photodynamic activity of amphiphilic zinc(II) phthalocyanines substituted with 2-(dimethylamino)ethylthio moieties and their N-alkylated derivatives

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 7, 2010, Pages 2672-2677

  Duan, Wubiao ^a   Lo, Pui Chi ^a   Duan, Lei ^a   Fong, Wing Ping ^a   Ng, Dennis K P ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Photodynamic therapy; Photosensitizers; Phthalocyanines; Singlet oxygen

Indexed keywords

ALKYL GROUP; AMINE; AMPHOPHILE; HETEROCYCLIC COMPOUND; METHYL GROUP; N,N DIMETHYLFORMAMIDE; PHTHALOCYANINE DERIVATIVE; POTASSIUM CARBONATE; SINGLET OXYGEN; ZINC DERIVATIVE;

ABSORPTION SPECTROSCOPY; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; CYCLIZATION; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; METHYLATION; PENTYLATION; PHOTODYNAMICS; PHOTOSENSITIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTUM YIELD; REACTION ANALYSIS; TEMPERATURE DEPENDENCE;

ALKYLATION; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; DIMETHYLAMINES; DRUG SCREENING ASSAYS, ANTITUMOR; HT29 CELLS; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; PHOTOSENSITIZING AGENTS; SPECTROMETRY, FLUORESCENCE;

EID: 77950036829     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.02.020     Document Type: Article

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