Molecular characterization of resistance to Rifampicin in an emerging hospital-associated methicillin-resistant staphylococcus aureus clone ST228, Spain

BMC Microbiology

Volumn 10, Issue , 2010, Pages

  Mick, Virginie ^a   Domínguez, M Angeles ^a   Tubau, Fe ^a,b   Liñares, Josefina ^a,b   Pujol, Miquel ^a   Martín, Rogelio ^a  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; HISTIDINE; RIFAMPICIN; RNA POLYMERASE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; TUBERCULOSTATIC AGENT;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BETA CHAIN; CONTROLLED STUDY; DILUTION; DISK DIFFUSION; EPSILOMETER TEST; GENE MUTATION; GENOTYPE; HOSPITAL INFECTION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR TYPING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; RPOB GENE; SPAIN; STAPHYLOCOCCUS AUREUS; BACTERIUM IDENTIFICATION; CROSS INFECTION; DRUG EFFECT; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METHODOLOGY; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MOLECULAR EPIDEMIOLOGY; MUTATION; NUCLEIC ACID AMPLIFICATION; STAPHYLOCOCCUS INFECTION;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTITUBERCULAR; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; CROSS INFECTION; DRUG RESISTANCE, BACTERIAL; HUMANS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR EPIDEMIOLOGY; MUTATION; NUCLEIC ACID AMPLIFICATION TECHNIQUES; RIFAMPIN; SPAIN; STAPHYLOCOCCAL INFECTIONS;

EID: 77949929236     PISSN: 14712180     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-10-68     Document Type: Article

References (38)

1. Control of methicillin-resistant Staphylococcus aureus in Spanish hospitals. A survey from the MRSA 2003 GEIH/GEMARA/REIPI Project. J Rodríguez-Baño AB Millán MA Domínguez B Almirante E Cercenado B Padilla M Pujol, Enferm Infecc Microbiol Clin 2006 24 149 156
2. Molecular epidemiology of methicillin-resistant Staphylococcus aureus in Spain: a multicentre prevalence study (2002). O Cuevas E Cercenado E Bouza C Castellares P Trincado R Cabrera A Vindel, Clin Microbiol Infect 2007 13 250 56
3. Spread and maintenance of a dominant methicillin-resistant Staphylococcus aureus clone during an outbreak of MRSA disease in a Spanish hospital. MA Domínguez H De Lencastre J Linares A Tomasz, J Clin Microbiol 1994 32 2081 87
4. Detection of an archaic clone of Staphylococcus aureus with low-level resistance to methicillin in a pediatric hospital in Portugal and in international samples: relics of a formerly widely disseminated strain? R Sá-Leao I Santos Sanches D Dora Dias I Peres RM Barros H De Lencastre, J Clin Microbiol 1999 37 1913 20 10325346
5. Changes in the clonal nature and antibiotic resistance profiles of methicillin-resistant Staphylococcus aureus isolates associated with spread of the EMRSA-15 clone in a tertiary-care Portuguese Hospital. ML Amorim NA Faria DC Oliveira C Vasconcelos JC Cabeda AC Mendes E Calado AP Castro MH Ramos JM Amorim H De Lencastre, J Clin Microbiol 2007 45 2881 88
6. Emergence and spread of gentamicin susceptible strains of methicillin-resistant Staphylococcus aureus in Belgian hospitals. O Denis A Deplano R De Ryck C Nonhoff MJ Struelens, Microb Drug Resist 2003 9 61 71
7. Changes in staphylococcal cassette chromosome type and antibiotic resistance profile in methicillin-resistant Staphylococcus aureus isolates from a French hospital over an 11 year period. PY Donnio L Preney AL Gautier-Lerestif JL Avril N Lafforgue, J Antimicrob Chemother 2004 53 808 13
8. Changes in the epidemiology of methicillin-resistant S. aureus associated with the emergence of EMRSA-16 at a university hospital. I Montesinos T Delgado D Riverol E Salido MA Miquel A Jimenez A Sierra, J Hosp Infect 2006 64 257 63
9. Prevalence and evolution of methicillin-resistant Staphylococcus aureus in Spanish hospitals between 1996 and 2002. A Vindel P Trincado E Gomez R Cabrera T Boquete C Sola S Valdezate JA Saez-Nieto, J Clin Microbiol 2006 44 266 70
10. Changing pattern of antibiotic resistance in methicillin-resistant Staphylococcus aureus from German hospitals. W Witte C Braulke C Cuny D Heuck M Kresken, Infect Control Hosp Epidemiol 2001 22 683 86
11. Clinical and Laboratory Standards Institute, Performance standards for antimicrobial susceptibility testing. Sixteenth informational supplement M100-S17 CLSI, Wayne, PA, USA 2007
12. Nucleotide sequence of the Staphylococcus aureus RNA polymerase rpoB gene and comparison of its predicted amino acid sequence with those of other bacteria. M Aboshkiwa G Rowland G Coleman, Biochem 1995 1262 73 78
13. Characterization of mutations in the rpoB gene that confer rifampin resistance in Staphylococcus aureus. H Aubry-Damon CJ Soussy P Courvalin, Antimicrob Agents Chemother 1998 42 2590 94
14. Role of rifampin for treatment of orthopedic implant-related staphylococcal infections. W Zimmerli AF Widmet M Blatter R Frei PE Ochsner, JAMA 1998 279 1537 41
15. Oral treatment of Staphylococcus spp. infected orthopedic implants with fusidic acid or ofloxacin in combination with rifampicin. M Drancourt A Stein JN Argenson R Roiron P Groulier D Raoult, J Antimicrob Chemother 1997 39 235 40
16. Current treatment options for community-acquired methicillin-resistant Staphylococcus aureus infection. RC Moellering, Clin Infect Dis 2008 46 1032 37
17. Molecular characterization of rpoB mutations conferring cross-resistance to rifamycins on methicillin-resistant Staphylococcus aureus. TA Wichelhaus V Shäfer V Brade B Böddinghaus, Antimicrob Agents Chemother 1999 43 2813 16
18. Multilocus sequence typing (MLST) shows that the 'Iberian' clone of methicillin-resistant Staphylococcus aureus has spread to France and acquired reduced susceptibility to teicoplanin. B Heym M Le Moal L Armand-Lefevre MH Nicolas-Chanoine, J Antimicrob Chemother 2002 50 323 29
19. The evolution of pandemic clones of methicillin resistant Staphylococcus aureus : identification of two ancestral genetic backgrounds and the associated mec elements. DC Oliveira A Tomasz H De Lencastre, Microb Drug Resist 2001 7 349 61
20. Molecular typing of Methicillin-resistant Staphylococcus aureus (MRSA) by pulsed field gel electrophoresis: comparison of results obtained in a multilaboratory effort using identical protocols and MRSA strains. M Chung H De Lencastre P Matthews A Tomasz I Adamsson M Aires de Sousa C Cocuzza A Corso I Couto MA Dominguez M Gniadkowski R Goering A Gomes M Hortal D Kikuchi A Marchese R Mato O Melter D Oliveira R Sa-Leao JH Song P Tassios P Villari, Microb Drug Resist 2000 6 189 97
21. Harmonization of pulsed-field gel electrophoresis protocols for epidemiological typing of strains of methicillin-resistant Staphylococcus aureus : a single approach developed by consensus in 10 European laboratories and its application for tracing the spread of related strains. S Murchan ME Kaufmann A Deplano R De Ryck M Struelens CE Zinn V Fussing S Salmenlinna J Vuopio-Varkila N El Solh C Cuny W Witte PT Tassios N Legakis W Van Leeuwen A Van Belkum A Vindel I Laconcha J Garaizar S Haeggman B Olsson-Liljequist U Ransjo G Coombes B Cookson, J Clin Microbiol 2003 41 1574 85
22. Guidelines for the validation and application of typing methods for use in bacterial epidemiology. A Van Belkum PT Tassios L Dijkshoorn S Haeggman B Cookson NK Fry V Fussing J Green E Feil P Gerner-Smidt S Brisse M Struelens, Clin Microbiol Infect 2007 13 1 46
23. Update to the multiplex PCR strategy for assignment of mec element types in Staphylococcus aureus. C Milheirico DC Oliveira H De Lencastre, Antimicrob Agents Chemother 2007 51 3374 77
24. Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus. DC Oliveira H De Lencastre, Antimicrob Agents Chemother 2002 46 2155 61
25. Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus. MC Enright NP Day CE Davies SJ Peacock BG Spratt, J Clin Microbiol 2000 38 1008 15 10698988
26. Molecular typing of methicillin-resistant Staphylococcus aureus on the basis of protein A gene polymorphism. HM Frénay AE Bunschoten LM Schouls WJ Van Leeuwen CM Vandenbroucke-Grauls J Verhoef FR Mooi, Eur J Clin Microbiol Infect Dis 1996 15 60 64
27. Biological cost of rifampin resistance from the perspective of Staphylococcus aureus. TA Wichelhaus B Böddinghaus S Besier V Shäfer V Brade A Ludwigh, Antimicrob Agents Chemother 2002 46 3381 85
28. Evolution of the antimicrobial resistance of Staphylococcus spp. in Spain: five nationwide prevalence studies, 1986 to 2002. O Cuevas E Cercenado A Vindel J Guinea M Sanchez-Conde M Sanchez-Somolinos E Bouza, Antimicrob Agents Chemother 2004 48 4240 45
29. Tracking methicillin-resistant S. aureus clones during a 5-year period (1998 to 2002) in a Spanish hospital. E Perez-Roth F Lorenzo-Diaz N Batista A Moreno S Mendez Alvarez, J Clin Microbiol 2004 42 4649 56
30. Adjunctive use of rifampin for the treatment of S. aureus infections. J Perlroth M Kuo J Tan AS Bayer LG Miller, Arch Intern Med 2008 168 805 19
31. Antibiotics for treatment of infections caused by MRSA and elimination of MRSA carriage. What are the choices? FJ Schmitz ME Jones, Int J Antimicrob Agents 1997 9 1 19
32. Emergence of rifampicin resistance in methicillin-resistant Staphylococcus aureus in tuberculosis wards. J Sekiguchi T Fujino M Araake E Toyota K Kudo K Saruta H Yoshikura T Kuratsuji T Kirikae, J Infect Chemother 2006 12 47 50
33. Molecular evolution of methicillin-resistant Staphylococcus aureus in the metropolitan area of Cologne, Germany, from 1984 to 1998. H Wisplinghoff B Ewertz S Wisplinghoff D Stefanik G Plum F Perdreau-Remington H Seifert, J Clin Microbiol 2005 43 5445 51
34. Clonal types and multidrug resistance patterns of methicillin-resistant Staphylococcus aureus (MRSA) recovered in Italy during the 1990s. R Mato F Campanile S Stefani MI Crisostomo M Santagati SI Sanches H De Lencastre, Microb Drug Resist 2004 10 106 13
35. Nationwide trends in molecular epidemiology of methicillin-resistant Staphylococcus aureus, Finland, 1997-2004. A Kerttula O Lyytikäinen M Kardén-Lilja S Ibrahem S Salmenlinna A Virolainen J Vuopio-Varkila, BMC Infectious Diseases 2007 7 1 9
36. Replacement of methicillin-resistant Staphylococcus aureus clones in Hungary over time: a 10-year surveillance study. T Conceiço M Aires-de-Sousa M Füzi A Táth J Pszti E Ungvri WB Van Leeuwen A Van Belkum H Grundmann H De Lencastre, Clin Microbiol Infect 2007 13 971 79
37. The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA). MC Enright DA Robinson G Randle EJ Feil H Grundmann BG Spratt, Proc Natl Acad Sci 2002 99 7687 92
38. High prevalence in cystic fibrosis patients of multiresistant hospital-acquired methicillin-resistant Staphylococcus aureus ST228-SCCmec I capable of biofilm formation. A Molina R Del Campo L Miz MI Morosini A Lamas F Baquero R Cantán, J Antimicrob Chemother 2008 62 961 67