Inhibition of tubulogenesis and of carcinogen-mediated signaling in brain endothelial cells highlight the antiangiogenic properties of a mumbaistatin analog

Chemical Biology and Drug Design

Volumn 75, Issue 5, 2010, Pages 481-488

  Tahanian, Elizabeth ^a   Lord Dufour, Simon ^a   Das, Abhirup ^b   Khosla, Chaitan ^b   Roy, René ^a   Annabi, Borhane ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Angiogenesis; Brain endothelial cells; Carcinogenesis; COX 2; G6PT inhibitors; MMP 9

Indexed keywords

AD 4 015; ANGIOGENESIS INHIBITOR; CARCINOGEN; CHLOROGENIC ACID; CYCLOOXYGENASE 2; GELATINASE B; GLUCOSE 6 PHOSPHATE TRANSLOCASE; I KAPPA B; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATE TRANSPORTER; UNCLASSIFIED DRUG;

ANTIANGIOGENIC ACTIVITY; ARTICLE; BRAIN BLOOD VESSEL; BRAIN CELL; BRAIN TUMOR; CANCER INHIBITION; CARCINOGENESIS; CELL FUNCTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG STRUCTURE; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MIGRATION INHIBITION; MORPHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR PROMOTION; TUMOR VASCULARIZATION; ZYMOGRAPHY;

ANGIOGENESIS INHIBITORS; ANTHRAQUINONES; ANTIPORTERS; BRAIN; CARCINOGENS; CELL MOVEMENT; CHLOROGENIC ACID; CYCLOOXYGENASE 2; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; I-KAPPA B KINASE; MATRIX METALLOPROTEINASE 9; MONOSACCHARIDE TRANSPORT PROTEINS; SIGNAL TRANSDUCTION;

EID: 77949921050     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.00961.x     Document Type: Article

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