SCOPUS 정보 검색 플랫폼

Volumn 21, Issue 5, 2010, Pages 554-557

Design, synthesis and antitumor activity of 6,7-disubstituted-4-(heteroarylamino)quinoline-3-carbonitrile derivatives

Author keywords

3 Quinolinecarbonitrile derivatives; Antitumor; Synthesis

Indexed keywords

EID: 77949915248 PISSN: 10018417 EISSN: None Source Type: Journal
DOI: 10.1016/j.cclet.2010.01.016 Document Type: Article

Times cited : (9)

References (8)

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7
- 77949915989
- The data of selected compounds: 12a: mp: 183-186 °C. IR (KBr, 3371, 3191, 2948, 2839, 2203, 1626, 1463, 745 cm-1, 1H NMR (300 MHz, DMSO-d6, δ 2.24(s, 3H, CH3N, 2.48(s, 3H, CH3, 2.46-2.51 (m, 6H, CH2, 2.78(m, 4H, CH2, 7.55(s, 2H, NH2, 7.17(dd, 1H, H-5′, J1, 1.8, J2, 8.4, 7.36(d, 1H, H-4′, J, 8.4, 7.66(d, 1H, H-7′, J, 1.8, 7.89(s, 1H, H-5, 8.37(s, 1H, H-8, 8.82(s, 1H, H-2, 9.57(s, 1H, NH, 10.67(s, 1H, CONH, 13C NMR(DMSO-d6, δ 19.5, 48.3, 52.7, 55.4, 57.2, 87.5, 112.9, 116.2, 120.2, 120.8, 121.3, 123.9, 124.4, 125.0, 126.8, 128.7, 131.8, 133.4, 135.3, 150.5,150.8, 154.7, 169.8; MS (EI, m/z, 500.2 (M, Anal. Calcd. for C25H26N8OS.HCl: C 57.41, H 5.20, N 21.42; Found: C 57.57, H 5.36, N 21.70. 12h: mp: 168-170 °C. IR KBr, 3421, 3047, 2792, 2204, 1608, 1522
- 7OS.HCl: C, 60.91; H, 6.21, N, 17.76; Found: C, 60.84; H, 6.53, N, 17.41.

8
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- Wissner, A.¹ Overbeek, E.² Reich, M.F.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.