Analysis of binding sites on complement factor I that are required for its activity

Journal of Biological Chemistry

Volumn 285, Issue 9, 2010, Pages 6235-6245

  Nilsson, Sara C ^a   Nita, Izabela ^a   Månsson, Lisa ^a   Groeneveld, Tom W L ^a   Trouw, Leendert A ^b   Villoutreix, Bruno O ^c   Blom, Anna M ^a  

^a LUND UNIVERSITY   (Sweden)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEINS; COFACTORS; EUKARYOTIC CELLS; HEAVY CHAIN; INITIAL VELOCITIES; LIGHT CHAIN; LOW DENSITY LIPOPROTEIN RECEPTORS; MEMBRANE ATTACK COMPLEXES; MICHAELIS CONSTANTS; POTENTIAL BINDING SITES; SERINE PROTEASE; TWO CHAINS;

AMINO ACIDS; BINDING ENERGY; BIOCHEMISTRY; ORGANIC ACIDS; PHOSPHATASES; PROTEINS;

BINDING SITES;

AMINO ACID; CD5 ANTIGEN; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C4B; COMPLEMENT FACTOR I; FI MEMBRANE ATTACK DOMAIN PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR 1; LOW DENSITY LIPOPROTEIN RECEPTOR 2; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL FUNCTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; EUKARYOTIC CELL; GENE MUTATION; HUMAN; HUMAN CELL; PREDICTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PURIFICATION; VELOCITY; CATALYSIS; CHEMISTRY; GENETICS; KINETICS; METABOLISM; SITE DIRECTED MUTAGENESIS; STRUCTURAL HOMOLOGY;

EUKARYOTA;

BINDING SITES; CATALYSIS; COMPLEMENT C3B; COMPLEMENT C4B; COMPLEMENT FACTOR I; HUMANS; KINETICS; MUTAGENESIS, SITE-DIRECTED; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 77949909418     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.097212     Document Type: Article

References (36)

1. Walport, M. J. (2001) N. Engl. J. Med. 344, 1058-1066
2. Sjöberg, A. P., Trouw, L. A., and Blom, A. M. (2009) Trends Immunol. 30, 83-90
3. Weiler, J. M., Daha, M. R., Austen, K. F., and Fearon, D. T. (1976) Proc. Natl. Acad. Sci. U.S.A. 73, 3268-3272
4. Gigli, I., Fujita, T., and Nussenzweig, V. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 6596-6600
5. Seya, T., Turner, J. R., and Atkinson, J. P. (1986) J. Exp. Med. 163, 837-855
6. Medof, M. E., and Nussenzweig, V. (1984) J. Exp. Med. 159, 1669-1685
7. Vyse, T. J., Morley, B. J., Bartok, I., Theodoridis, E. L., Davies, K. A., Webster, A. D., and Walport, M. J. (1996) J. Clin. Invest. 97, 925-933
8. Amadei, N., Baracho, G. V., Nudelman, V., Bastos, W., Florido, M. P., and Isaac, L. (2001) Scand. J. Immunol. 53, 615-621
9. Nilsson, S. C., Trouw, L. A., Renault, N., Miteva, M. A., Genel, F., Zelazko, M., Marquart, H., Muller, K., Sjöholm, A. G., Truedsson, L., Villoutreix, B. O., and Blom, A. M. (2009) Eur. J. Immunol. 39, 310-323
10. Sadallah, S., Gudat, F., Laissue, J. A., Spath, P. J., and Schifferli, J. A. (1999) Am. J. Kidney Dis. 33, 1153-1157
11. Fremeaux-Bacchi, V., Dragon-Durey, M. A., Blouin, J., Vigneau, C., Kuypers, D., Boudailliez, B., Loirat, C., Rondeau, E., and Fridman, W. H. (2004) J. Med. Genet. 41, e84
12. Kavanagh, D., Richards, A., Noris, M., Hauhart, R., Liszewski, M. K., Karpman, D., Goodship, J. A., Fremeaux-Bacchi, V., Remuzzi, G., Goodship, T. H., and Atkinson, J. P. (2008) Mol. Immunol. 45, 95-105
13. Nilsson, S. C., Karpman, D., Vaziri-Sani, F., Kristoffersson, A. C., Salomon, R., Provot, F., Fremeaux-Bacchi, V., Trouw, L. A., and Blom, A. M. (2007) Mol. Immunol. 44, 1835-1844
14. Nilsson, S. C., Kalchishkova, N., Trouw, L. A., Fremeaux-Bacchi, V., Villoutreix, B. O., and Blom, A. M. (2009) Eur. J. Immunol. 40, 172-185
15. Tsiftsoglou, S. A., Arnold, J. N., Roversi, P., Crispin, M. D., Radcliffe, C., Lea, S. M., Dwek, R. A., Rudd, P. M., and Sim, R. B. (2006) Biochim. Biophys. Acta 1764, 1757-1766
16. Fearon, D. T. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 5867-5871
17. Chamberlain, D., Ullman, C. G., and Perkins, S. J. (1998) Biochemistry 37, 13918-13929
18. Tsiftsoglou, S. A., Willis, A. C., Li, P., Chen, X., Mitchell, D. A., Rao, Z., and Sim, R. B. (2005) Biochemistry 44, 6239-6249
19. Perkins, S. J., Smith, K. F., and Sim, R. B. (1993) Biochem. J. 295, 101-108
20. DiScipio, R. G. (1992) J. Immunol. 149, 2592-2599
21. Miteva, M. A., Tufféry, P., and Villoutreix, B. O. (2005) Nucleic Acids Res. 33, W372-W375
22. Fernandez-Recio, J., Totrov, M., Skorodumov, C., and Abagyan, R. (2005) Proteins 58, 134-143
23. Dahlbäck, B. (1983) Biochem. J. 209, 847-856
24. Blom, A. M., Kask, L., and Dahlbäck, B. (2003) Mol. Immunol. 39, 547-556
25. Greenwood, F. C., Hunter, W. M., and Glover, J. S. (1963) Biochem. J. 89, 114-123
26. Tsiftsoglou, S. A., and Sim, R. B. (2004) J. Immunol. 173, 367-375
27. Spiller, O. B., Blackbourn, D. J., Mark, L., Proctor, D. G., and Blom, A. M. (2003) J. Biol. Chem. 278, 9283-9289
28. Okroj, M., Hsu, Y. F., Ajona, D., Pio, R., and Blom, A. M. (2008) Mol. Immunol. 45, 169-179
29. Bahadur, R. P., and Zacharias, M. (2008) Cell Mol. Life Sci. 65, 1059-1072
30. Blom, A. M., Kask, L., and Dahlbäck, B. (2001) J. Biol. Chem. 276, 27136-27144
31. Krych, M., Hauhart, R., and Atkinson, J. P. (1998) J. Biol. Chem. 273, 8623-8629
32. Adams, E. M., Brown, M. C., Nunge, M., Krych, M., and Atkinson, J. P. (1991) J. Immunol. 147, 3005-3011
33. Wu, J., Wu, Y. Q., Ricklin, D., Janssen, B. J., Lambris, J. D., and Gros, P. (2009) Nat. Immunol. 10, 728-733
34. Ekdahl, K. N., Nilsson, U. R., and Nilsson, B. (1990) J. Immunol. 144, 4269-4274
35. Isenman, D. E. (1983) J. Biol. Chem. 258, 4238-4244
36. Thai, C. T., and Ogata, R. T. (2005) J. Immunol. 174, 6227-6232