17-alpha-hydroxyprogesterone caproate for the prevention of preterm birth in women with prior preterm birth and a short cervical length

American Journal of Obstetrics and Gynecology

Volumn 202, Issue 4, 2010, Pages 351.e1-351.e6

  Berghella, Vincenzo ^a   Figueroa, Dana ^b   Szychowski, Jeff M ^c   Owen, John ^b   Hankins, Gary D V ^d   Iams, Jay D ^e   Sheffield, Jeanne S ^f   Perez Delboy, Annette ^g   Wing, Deborah A ^h   Guzman, Edwin R ⁱ  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b Division of Maternal Fetal Medicine   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d University of Texas Medical Branch School of Medicine   (United States)

^e THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g Irvine ^*  (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ SAINT PETER S UNIVERSITY HOSPITAL   (United States)

Author keywords

cerclage; preterm birth; progesterone; short cervical length

Indexed keywords

HYDROXYPROGESTERONE CAPROATE;

ADULT; ARTICLE; CERCLAGE; CERVICAL LENGTH MEASUREMENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; PERINATAL DEATH; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 77949898739     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2010.02.019     Document Type: Article

References (22)

1. Iams J.D., Goldenberg R.L., Meis P.J., et al. The length of the cervix and the risk of spontaneous premature delivery. N Engl J Med 334 (1996) 567-572
2. Mercer B.M., Goldenberg R.L., Moawad A.H., et al. The preterm prediction study: effect of gestational age and cause of preterm birth on subsequent obstetric outcome. Am J Obstet Gynecol 181 (1999) 1216-1221
3. Owen J., Hankins G., Iams J.D., et al. Multicenter randomized trial of cerclage for preterm birth prevention in high-risk women with shortened midtrimester cervical length. Am J Obstet Gynecol 201 (2009) 375.e1-375.e8
4. Rust O.A., Atlas R.O., Reed J., van Gaalen J., and Balducci J. Revisiting the short cervix detected by transvaginal ultrasound in the second trimester: why cerclage therapy may not help. Am J Obstet Gynecol 185 (2001) 1098-1105
5. Althuisius S.M., Dekker G.A., Hummel P., Bekedam D.J., and van Geijn H.P. Final results of the cervical incompetence prevention randomized cerclage trial (CIPRACT): therapeutic cerclage with bed rest versus bed rest alone. Am J Obstet Gynecol 185 (2001) 1106-1112
6. To M.S., Alfirevic Z., Heath V.C.F., Cacho A.M., Williamson P.R., and Nicolaides K.H. Cervical cerclage for prevention of preterm delivery in women with short cervix: randomized controlled trial. Lancet 363 (2004) 1849-1853
7. Berghella V., Odibo A.O., and Tolosa J.E. Cerclage for prevention of preterm birth in women with a short cervix found on transvaginal ultrasound examination: a randomized trial. Am J Obstet Gynecol 191 (2004) 1311-1317
8. Berghella V., Odibo A.O., To M.S., Rust O.A., and Althuisius S.M. Cerclage for short cervix on ultrasonography: meta-analysis of trials using individual patient-level data. Obstet Gynecol 106 (2005) 181-189
9. Meis P.J., Klebanoff M., Thom E., et al. Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate. N Engl J Med 348 (2003) 2379-2385
10. MacKenzie R., Walker M., Armson A., and Hannah M.E. Progesterone for the prevention of preterm birth among women at increase risk: a systematic review and meta-analysis of randomized controlled trials. Am J Obstet Gynecol 194 (2006) 1234-1242
11. Owen J., Yost N., Berghella V., et al. Mid-trimester endovaginal sonography in women at high risk for spontaneous preterm birth. JAMA 286 (2001) 1340-1348
12. Fonseca E., Celik E., Parra M., Singh M., and Nicolaides K.H. Progesterone and the risk of preterm birth among women with a short cervix. N Engl J Med 357 (2007) 462-469
13. American College of Obstetricians and Gynecologists. Use of progesterone to reduce preterm birth: ACOG committee opinion no. 419. Obstet Gynecol 112 (2008) 963-965
14. DeFranco E.A., O'Brien J.M., Adair C.D., et al. Vaginal progesterone is associated with a decrease in risk for early preterm birth and improved neonatal outcome in women with a short cervix: a secondary analysis from a randomized, double-blind, placebo-controlled trial. Ultrasound Obstet Gynecol 30 (2007) 697-705
15. Rebarber A., Cleary-Goldman J., Istwan N.B., et al. The use of 17 alpha-hydroxyprogesterone caproate (17P) in women with cervical cerclage. Am J Perinatol 25 (2008) 271-275
16. Keeler S.M., Kiefer D., Rochon M., Quinones J.N., Novetsky A.P., and Rust O. A randomized trial of cerclage vs 17 α-hydroxyprogesterone caproate for treatment of short cervix. J Perinat Med 37 (2009) 473-479
17. Durnwald C.P., Lynch C.D., Walker H., and Iams J.D. The effect of treatment with 17 alpha-hydroxyprogesterone caproate on changes in cervical length over time. Am J Obstet Gynecol 201 (2009) 410.e1-410.e5
18. O'Brien J.M., DeFranco E.A., Adair C.D., et al. effect of progesterone on cervical shortening in women at risk for preterm birth: secondary analysis from a multinational, randomized, double-blind, placebo-controlled trial. Ultrasound Obstet Gynecol 34 (2009) 653-659
19. Facchinetti F., Paganelli S., Comitini G., Dante G., and Volpe A. Cervical length changes during preterm cervical ripening: effects of 17 alpha hydroxyprogesterone caproate. Am J Obstet Gynecol 453 (2007) e1-e4
20. Kiefer D.G., Keeler S.M., Rust O.A., Waycock C.P., Vintzileos A.M., and Hanna N. Is midtrimester short cervix a sign of intraamniotic inflammation?. Am J Obstet Gynecol 200 (2009) 374.e1-374.e5
21. Romero R., Espinosa J., Erez O., and Hassan S. The role of cervical cerclage in obstetric practice: can the patient who could benefit from this procedure be identified?. Am J Obstet Gynecol 194 (2006) 1-9
22. Sakai M., Shiozaki A., Tabata M., et al. Evaluation of effectiveness of prophylactic cerclage of a short cervix according to interleukin-8 in cervical mucus. Am J Obstet Gynecol 194 (2006) 14-19